Estimation of mangrove carbon stocks using unmanned aerial vehicle over coastal vegetation by S.H. Larekeng, M. Nursaputra, M.F. Mappiasse, S. Ishak, M. Basyuni, E. Sumarga, V.B. Arifanti, A.A. Aznawi, Y.I. Rahmila, M. Yulianti, R. Rahmania, A. Mubaraq, S.G. Salmo III, H. Ali, I. Yenny

“…BACKGROUND AND OBJECTIVES: Mangroves play a crucial role in mitigating climate change by absorbing carbon stocks. However, there is a lack of information on mangrove distribution and their carbon absorption abilities. …”
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The role of FTO in m6A RNA methylation and immune regulation in Staphylococcus aureus infection-related osteomyelitis by Sijing Liu, Sijing Liu, Sijing Liu, Kai Li, Changhai Long, Mingwu Lao, Biao Ma, Changquan Liu, Haoyuan He, Chunjiang Wang, Wangzhu Chen, Bin Yu

“…The western blotting and qPCR analyses confirmed that the protein expression of FTO was reduced in macrophages after infection with S. aureus, consistent with the observed changes in mRNA expression. Furthermore, we validated that FTO may influence the regulation of inflammation through the FoxO1/NF-kB pathway.ConclusionThe m6A RNA methylation regulator FTO may serve as a potential diagnostic marker and therapeutic target, involved in the pathogenesis of S. aureus infection-related osteomyelitis. …”
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Application of psychological intervention combined with wet compress of Traditional Chinese Medicine in nursing of patients with diabetic foot ulcer (心理干预联合中药塌渍技术在糖尿病足溃疡护理中的应用)... by WANG Xiuyan (王秀燕), CAO Hongjing (曹红京), LI Ning (李宁), LI Yueru (李月茹), LI Jing (李静), YANG Kun (杨坤), LI Lin (李林), TANG Hong (汤虹)

“…All patients received local dressing change in addition to the comprehensive treatment such as blood glucose control and infection prevention. …”
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Implications of water management on methane emissions and grain yield in paddy rice: A case study under subtropical conditions in Brazil using the CSM-CERES-Rice model by Evandro H. Figueiredo Moura da Silva, Gerrit Hoogenboom, Kenneth J. Boote, Santiago Vianna Cuadra, Cheryl H. Porter, Walkyria Bueno Scivittaro, Silvio Steinmetz, Carlos E. Pellegrino Cerri

“…However, rice cultivation is associated with significant methane (CH4) emissions, contributing to overall greenhouse gas emissions and, thus, climate change. In this context, process-based crop models are useful tools for understanding and predicting the complex interactions between crop production, environmental factors, and sustainability. …”
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Clinical Characteristics of Fulminant Type 1 Diabetes Compared with Typical Type 1 Diabetes: One-Year Follow-Up Study from the Guangdong T1DM Translational Medicine Study by Daizhi Yang, Yongwen Zhou, Sihui Luo, Xueying Zheng, Ping Ling, Liling Qiu, Wen Xu, Hua Liang, Bin Yao, Jianping Weng, Jinhua Yan

“…The level of HDL-C in FT1DM was significantly higher than that in the TT1DM group at enrollment (P=0.019), and the change from enrollment was significantly greater than that in the FT1DM group (P=0.042). …”
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MiR-9-z/zp2, miR-3154-y/zp2, and miR-3533-y/zp3 participated in ovarian development and adaptation to salinity stress in spotted scat (Scatophagus argus) by Zhuoying Leng, Xinghua Lin, Yi Zhai, Hongjuan Shi, Dongneng Jiang, Mouyan Jiang, Huapu Chen, Tianli Wu, Siping Deng

“…The dual-luciferase reporter assay, together with the changes observed in zp2, zp3, miR-9-z, miR-3154-y, and miR-3533-y after low and high salt treatment, demonstrated that zp2 expression was regulated by miR-9-z and miR-3154-y, while zp3 was regulated by miR-3533-y. …”
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Peritoneal chemotherapy delivery systems for ovarian cancer treatment: systematic review of animal models by Marcelo Simonsen, Marcelo Simonsen, Rossana Verónica Mendoza López, Simone Maistro, Lucas Takeshi Ikeoka, Glaucia Fernanda de Lima Pereira, Ademar Benévolo Lugão, José Carlos Sadalla, Maria Lúcia Hirata Katayama, Maria Aparecida Azevedo Koike Folgueira

“…The secondary aim was to assess the toxicity of DDS-delivered chemotherapy, based on changes in animal body weight.MethodsBased on PRISMA and SYRCLE guidelines, we identified 38 studies for review, of which 20, were used in the meta-analysis. …”
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Recommendations for the diagnosis and treatment of anti-neutrophil cytoplasmic autoantibody associated vasculitis by Enrique Morales, Iñigo Rúa-Figueroa, José Luis Callejas Rubio, Ana Ávila Bernabéu, Ricardo Blanco Alonso, María C. Cid Xutgla, Gema Fernández Juárez, Natalia Mena-Vázquez, Juan José Ríos Blanco, Joaquín Manrique Escola, F. Javier Narváez García, Bernardo Sopeña, Luis F. Quintana Porras, Susana Romero-Yuste, Roser Solans Laqué

“…Current treatment has changed ANCA-associated vasculitis into a condition with a significant response rate, although with a not negligible relapse occurrence and cumulative organ lesions, mostly due to drug-related toxicities. …”
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Coal mining-induced composite damage to geological bodies and geological guarantee against damage reduction by Shuangming WANG, Qiang SUN, Xin HU, Jishi GENG, Enke HOU, Shengquan WANG, Shutao ZHOU, Qingmin SHI, Shihao YUAN, Kai CHEN, Shijie SONG

“…It is supposed to, based on the correlations between multi-sphere damage under coal mining, pay much attention to the dynamic evolution process of composite damage and corresponding changes in key state parameters and, accordingly, establish a collaborative prediction, monitoring, and prevention system against composite damage in coal mining areas. …”
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Effect of a prepartum and postpartum, complex interdisciplinary lifestyle and psychosocial intervention on metabolic and mental health outcomes in women with gestational diabetes m... by Umberto Simeoni, Antje Horsch, Arnaud Chiolero, Yvan Vial, Nicole Sekarski, Jardena J Puder, Pascal Bovet, Yvan Mivelaz, Adina Mihaela Epure, Bobby Stuijfzand, Leah Gilbert, Stefano Lanzi, Justine Gross, Didier Hans, Stefano Di Bernardo, Elena Gonzalez-rodriguez, Alain Lacroix, Jean-Benoît Rossel, Dan Yedu Quansah, Amar Arhab, Sandrine Estoppey Younes, Seyda Mayerat

“…Secondary outcomes included changes in total and central body fat, anxiety, wellbeing, glycaemic parameters (homeostatic model assessment for insulin resistance (known as HOMA-IR) and Matsuda indices), aerobic fitness (maximal oxygen uptake), gestational weight gain, and weight retention. …”
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Efficacy and safety of Jianpi Qinghua granules for non-erosive reflux disease with spleen deficiency and damp-heat syndrome: a multicenter, randomized, double-blind, placebo-contro... by Tai Zhang, Tai Zhang, Tai Zhang, Tai Zhang, Guang Bai, Wei Wang, Lin Liu, Zhenghua Zhou, Haijie Ji, Beihua Zhang, Beihua Zhang, Beihua Zhang, Xudong Tang, Xudong Tang

“…Primary endpoints were the improvement rates of reflux and heartburn symptoms and VAS score changes. Secondary endpoints included atypical symptom scores, total TCM syndrome scores, GERD Health-Related Quality-of-Life (HRQL), and self-rated depression and anxiety scales. …”
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Comparative end-of-life communication and support in hospitalised decedents before and during the COVID-19 pandemic: a retrospective regional cohort study in Ottawa, Canada by Shirley H Bush, Monisha Kabir, Peter Lawlor, James Downar, Brandi Vanderspank-Wright, Sarina Isenberg, Peter Tanuseputro, Akshai Iyengar, Claire Dyason, Julie Lapenskie, Colleen Webber, Henrique Parsons, Samantha Rose Adeli, Ella Besserer, Leila Cohen, Valérie Gratton, Rebekah Murphy, Grace Warmels, Adrianna Bruni, Chelsea Noel, Brandon Heidinger, Koby Anderson, Kyle Arsenault-Mehta, Krista Wooller, Daniel Bedard, Paula Enright, Isabelle Desjardins, Khadija Bhimji

“…The implications of these communication changes for the patient, family and healthcare team warrant further study.…”
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Chaihu Shugan San and Zuogui Yin synergistically improve premature ovarian failure in a rat model via the PI3K/Akt/mTOR pathway by Fei Zhang, RuiFang Liu, ZhenLing Xu, WenJie Chen, XiYa Lu, Yang Wang

“…Key outcomes, including ovarian granulosa cell proliferation, follicular integrity, and hormonal levels (FSH and E2), were assessed. Histopathological changes in ovarian tissue were evaluated using hematoxylin and eosin (H&E) staining, while apoptosis was detected through immunohistochemistry and Western blot analysis of proteins such as Bcl-2, Bax, Caspase3, and Caspase9. …”
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Differences in Optical Two-dimensional Morphological Characteristics of Downward Lightning Channels with Different Polarities by Mei Ji, Lü Weitao, Qi Qi, Xu Weiqun, Wu Bin, Ma Ying, Liu Hengyi, Chen Lüwen, Zhang Yang

“…Compared to negative CG lightning, the return stroke channels of positive CG lightning tend to develop more inclinedly with fewer directional changes.There is no significant difference in relative length (the ratio of the straight-line distance from the cloud exit point of the return stroke channel to the strike point to the total length of the return stroke channel) of return stroke channels between downward positive and negative cloud-to-ground lightning.…”
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Effect of five-element cupping therapy on postoperative wound pain of patients with mixed hemorrhoids (五行能量罐治疗混合痔术后伤口疼痛效果观察) by WEI Yongchun (魏永春), QIN Shasha (秦沙沙), ZHANG Kaiye (张凯烨), WANG Yali (王亚丽), DONG Yuxia (董玉霞), E Haiyan (鄂海燕), TANG Ling (唐玲)

“…The control group received routine wound cleansing and dressing change, and the observation group received TCM five-element cupping therapy on the basis of routine care. …”
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Opposing trends in the peak and low ozone concentrations in eastern China: anthropogenic and meteorological influences by Z. Wang, Z. Wang, C. Shi, C. Shi, H. Zhang, H. Zhang, X. Ji, Y. Zhu, C. Xia, X. Sun, X. Sun, X. Lin, S. Yan, S. Wang, Y. Zhou, Y. Zhou, C. Xing, Y. Chen, Y. Chen, C. Liu, C. Liu, C. Liu, C. Liu

“…Our findings underscore the beneficial impacts of NO<span class="inline-formula">_<i>x</i></span> reduction on managing peak ozone levels. Regular changes in ozone formation sensitivity throughout the day should be considered when formulating effective ozone control policies.…”
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Process evaluation of Project Daire: a food environment intervention that impacted food knowledge, wellbeing and dietary habits of primary school children by Naomi Anderson, Sarah F. Brennan, Fiona Lavelle, Sarah E. Moore, Dilara Olgacher, Amy Junkin, Moira Dean, Michelle C. McKinley, Patrick McCole, Ruth F. Hunter, Laura Dunne, Niamh E. O’Connell, Chris T. Elliott, Danielle McCarthy, Jayne V. Woodside

“…Nourish schools delivered a higher mean dose of intervention elements (61.4%) than Engage (50%) schools but, overall, mixed implementation of both interventions occurred. DAIRE produced change through four key MOI: social learning, experimental learning, interactive engaging content and real-life connections. …”
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PD-L1/TLR7 dual-targeting nanobody-drug conjugate mediates potent tumor regression via elevating tumor immunogenicity in a host-expressed PD-L1 bias-dependent way by Wei Huang, Ji Zhou, Jia Li, Yakun Wan, Chao Hu, Meng Liu, Pan Xu, Feng Tang, Jianhua Sun, Xiaolu Yu, Yiru Long, Binfan Chen, Yongliang Tong, Mengwen Shan, Xiaomin Jia, Henglei Lu, Runqiu Chen, Jin Ren, Guangyi Jin, Likun Gong

“…The dynamics of the in vivo behaviors of NDCs were assessed based on multiorgan changes in PD-L1 levels.Results The screened PD-L1 nanobodies were characterized as tumor-targeting and alleviated T-cell immunosuppression. …”
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Analysis of early effects of human APOE isoforms on Alzheimer’s disease and type III hyperlipoproteinemia pathways using knock-in rat models with humanized APP and APOE by Metin Yesiltepe, Tao Yin, Marc Tambini, Hanmei Bao, Meixia Pan, Cristina d’Abramo, Luca Giliberto, Xianlin Han, Luciano D’Adamio

“…In this study, we focused on 80-day-old adolescent rats to analyze early changes that may be associated with the later development of LOAD. …”
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Virological Aspects of COVID-19 in Patients with Hematological Malignancies: Duration of Viral Shedding and Genetic Analysis by Asma Themlaoui, Massimo Ancora, Kais Ghedira, Yosra Mhalla, Manel Hamdoun, Maroua Bahri, Lamia Aissaoui, Raihane Ben Lakhal, Adriano Di Pasquale, Cesare Camma, Olfa Bahri

“…Sequence analysis revealed the inclusion of one to eight amino acid-changing events in seventeen cases; it was characterized by genetic stability from the third to the twentieth day of evolution in six cases. …”
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