Modelling the air quality impacts of a zero emission zone scenario in the city of Milan by Andrea Piccoli, Valentina Agresti, Marco Bedogni, Giovanni Lonati, Guido Pirovano

“…The goal of this work is to simulate a 2030 ZEZ mobility scenario in Milan city centre (Italy), introducing changes to the vehicle fleet composition within the ZEZ, as suggested by the Air Quality and Climate Plan of the municipality. …”
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Assessing Heat Resistance and Selecting Heat-Resistant Individuals of Largemouth Bass (<i>Micropterus salmoides</i>) with Tiered Thermal Exposure by Haijie Chen, Hui Qiao, Zhicheng Xv, Guili Song, Shuning Liu, Cheng Luo, Yong Long, Shimei Lin

“…The heat resistance of the fish was quantified as the lethal cumulative temperature (LCT), allowing for the classification of fish as sensitive or resistant to heat stress based on their LCT values. To correlate the changes in tissue structure and gene expression with the heat resistance, a new batch of LMB juveniles (average body weight 23.66 ± 6.98 g) were subjected to tiered heat exposure. …”
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Integrated Impacts of Urban Spatial Form on Thermal Environment and Zonal Regulation under the Perspective of Spatial Heterogeneity by Yan Jinlong, Yin Chaohui, An Zihao, Zhang Simin, Wen Qian, Chen Weiqiang

“…Finally, according to the MGWR regression coefficients of each indicator, the main urban area of Wuhan was divided into four types of impact zones, and the intensity and direction of the impact of indicators in different impact zones changed, which confirms the necessity of a zoning policy. 3D buildings form the dominant zone and the BD strong dominant zone are suggested to adjust the urban building form as the main goal, the percentage of water area and BD co-dominant zones are suggested to optimize the urban blue-green space as the main regulation goal to improve its cooling efficiency, and the integrated transition zone is suggested to synergistically optimize the 2D/3D urban spatial form. …”
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Mechanism of Bushen Huoxue Recipe on Improving Arterial Calcification in Rats with Osteoporosis Based on OPG/RANKL Signaling Pathway by LIN Xiaorong, YANG Na, ZHENG Bei, ZHAO Hu, XU Junxia

“…Dual-energy X-ray absorptiometry was used to measure the bone mass density (BMD) of femoral shaft of right hindlimb; alizarin red staining was used to detect integrated optical density (IOD) of calcification deposition on the vascular wall of thoracic aorta, and the calcification degree of thoracic aorta was observed; ELISA method was used to detect serum levels of PⅠNP, BGP and CTX-Ⅰ; immunohistochemical staining was used to detect the expression of OPG and RANKL proteins in thoracic aorta.Results1) BMD and IOD value of thoracic aorta calcification deposition: compared with the control group, there were no significant changes of BMD and IOD value in thoracic aorta calcification deposition of the sham operation group (<italic>P</italic>&gt;0.05), while the BMD of the osteoporosis group decreased significantly, and the IOD value of thoracic aorta calcification deposition increased significantly (<italic>P</italic>&lt;0.05). …”
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Enhanced therapeutic effects of hypoxia-preconditioned mesenchymal stromal cell-derived extracellular vesicles in renal ischemic injury by Fei Yuan, Jie Liu, Liang Zhong, Pengtao Liu, Ting Li, Kexin Yang, Wei Gao, Guangyuan Zhang, Jie Sun, Xiangyu Zou

“…Proliferation and related pathways were measured, and RNA sequencing was used to detect changes in the transcriptional profile. MSC-EVs from both normoxic and hypoxic conditions were isolated and characterized. …”
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Searching for new genes associated with the familial hypercholesterolemia phenotype using whole-genome sequencing and machine learning by D. E. Ivanoshchuk, A. B. Kolker, O. V. Timoshchenko, S. E. Semaev, E. V. Shakhtshneider

“…In 20–40 % of cases, molecular genetic testing fails to detect changes in the above genes. The aim of this work was to search for new genes associated with the familial hypercholesterolemia phenotype by modern high-tech methods of sequencing and machine learning. …”
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Linking weather and climate information services (WCIS) to Climate-Smart Agriculture (CSA) practices by Tafadzwanashe Mabhaudhi, Tinashe Lindel Dirwai, Cuthbert Taguta, Aidan Senzanje, Wuletawu Abera, Ajit Govid, Elliott Ronald Dossou-Yovo, Ermias Aynekulu, Vimbayi Grace Petrova Chimonyo

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The effect of single and dual task training on the intracortical inhibition in young and old adults by Michael Wälchli, Craig Tokuno, Benedikt Lauber, Wolfgang Taube

“…This result is supported by the modulation of SICI. The changes were age-specific, with no improvements for the older groups. …”
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Evaluasi Maturitas Teknologi Informasi Pada Proses Problem Management PT. XYZ Menggunakan Kerangka Kerja COBIT 5 by Muhammad Naufal Pratama, Andi Reza Perdanakusuma, Aditya Rachmadi

“…Abstract Technology is developing rapidly to the point where the role of information technology is increasingly crucial and could influence and change the way an organization operates, in empowering information technology, IT governance needs to regulate and make law as a guide for the implementation and application of information technology. …”
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Efficacy of Unsupervised YouTube Dance Exercise for Patients With Hypertension: Randomized Controlled Trial by Mizuki Sakairi, Taiju Miyagami, Hiroki Tabata, Naotake Yanagisawa, Mizue Saita, Mai Suzuki, Kazutoshi Fujibayashi, Hiroshi Fukuda, Toshio Naito

“…The exclusion criteria were the absence of BP data, medication changes, or withdrawal from the study. The mean age was 56 (SD 9.8) years, and 18 (53%) of the patients were female. …”
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RETRACTED ARTICLE: Research on the efficacy of Celastrus Orbiculatus in suppressing TGF-β1-induced epithelial-mesenchymal transition by inhibiting HSP27 and TNF-α-induced NF-κB/Sna... by Yaodong Zhu, Yanqing Liu, Yayun Qian, Xiaojun Dai, Ling Yang, Jue Chen, Shiyu Guo, Tadashi Hisamitsu

“…Results The non-cytostatic concentrations of COE effectively inhibited TGF-β1 induced EMT process in SGC-7901 cells, which is characterized by prevented morphological changes, increased E-cadherin expression and decreased Vimentin, N-cadherin expression. …”
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Productivity and ecological functions of naturally regrown pine forests of the Ukrainian Polissia by Petro Lakyda, Volodymyr Blyshchyk

“…Increasing the forest cover of the territory of Ukraine and bringing it to optimal parameters in the conditions of global climate change, the aggressive war of Russia against both the Ukrainian society and the environment, requires the search for adequate mechanisms for preservation and reproduction of forest formations. …”
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Analisis Tren dan Perkiraan Pandemi COVID-19 di Indonesia Menggunakan Peramalan Metode Prophet :Sebelum dan Sesudah Aturan New Normal by Mawaddah Harahap, Ahmad Zaki Andika, Amir Mahmud Husein, Abdi Dharma

“…In addition, the uncertainty about the end of this pandemic has resulted in changing social conditions. This paper aims to facilitate a comparison between the PSBB and New Normal regulations on the development of the number of Covid-19 cases in Indonesia by mapping the cumulative number of cases (active, cured, confirmed and death cases). …”
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Mental health in the COVID-19 pandemic: A longitudinal analysis of the CLoCk cohort study. by Laura Panagi, Simon R White, Snehal M Pinto Pereira, Manjula D Nugawela, Isobel Heyman, Kishan Sharma, Terence Stephenson, Trudie Chalder, Natalia K Rojas, Emma Dalrymple, Kelsey McOwat, Ruth Simmons, Olivia Swann, CLoCk Consortium, Tamsin Ford, Roz Shafran

“…There was no evidence of differences in rate of change in total SDQ by ethnicity, SES, or physical health. …”
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Effect of intravitreal injections on the progression and prognosis of primary open-angle glaucoma by A.B. Movsisyan, N.G. Glazko, A.Yu. Brezhnev, A.V. Kuroyedov

“…Understanding the results and ocular changes in response to therapy (particularly in patients with glaucoma) requires special attention. …”
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Impaired Mitochondrial Bioenergetics Function in Pediatric Chronic Overlapping Pain Conditions with Functional Gastrointestinal Disorders by Gisela Chelimsky, Pippa Simpson, Liyun Zhang, Doug Bierer, Steve Komas, Balaraman Kalyanaraman, Thomas Chelimsky

“…Predisposing genetic factors or reversible acquired changes may be responsible. A higher SRC best predicts disability. …”
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Protective Effects of Gynostemma pentaphyllum Saponins on Liver Injury in Guinea Pigs of Hyperlipemia Based on Oxidative Stress by Tianyi DAI, Donglian LIU, Xingmin QIN, Chengling GAO, Jiayi LI, Hailing KUANG

“…HE and oil red staining were used to observe the pathological and morphological changes of guinea pig liver tissue. Immunofluorescence method was used to observe the protein expression of Nrf2 and HO-1 in the liver of guinea pigs. …”
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Analysis of the Inquiry-Infusion learning model to develop students' critical thinking ability by Beni Asyhar

“…The 21st century demands a change in student-centered learning processes to support 21st century competencies and skills. …”
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Integrated transcriptomic hypothalamic-pituitary-ovarian axis network analysis reveals the role of energy availability on egg production in layers by Jianling Peng, Yong Cui, Haiping Liang, Shenyijun Xu, Linjian Weng, Meng Ru, Ramlat Ali, Qing Wei, Jiming Ruan, Jianzhen Huang

“…In addition, estradiol (E2), estradiol to progesterone (E2/P4) ratio, and luteinizing hormone (LH) displayed changes similar to follicle number, whereas follicle-stimulating hormone (FSH) exhibited a contrasting pattern. …”
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Lifestyle risk behaviours among adolescents: a two-year longitudinal study of the impact of the COVID-19 pandemic by Nicola Clare Newton, Maree Teesson, Jennifer Debenham, Cath Chapman, Bridie Osman, Lauren Anne Gardner, Fiona Elizabeth Wylie, Katrina Elizabeth Champion

“…Objective To examine changes in the prevalence of six key chronic disease risk factors (the “Big 6”), from before (2019) to during (2021) the COVID-19 pandemic, among a large and geographically diverse sample of adolescents, and whether differences over time are associated with lockdown status and gender.Design Prospective cohort study.Setting Three Australian states (New South Wales, Queensland and Western Australia) spanning over 3000 km.Participants 983 adolescents (baseline Mage=12.6, SD=0.5, 54.8% girl) drawn from the control group of the Health4Life Study.Primary outcomes The prevalence of physical inactivity, poor diet (insufficient fruit and vegetable intake, high sugar-sweetened beverage intake, high discretionary food intake), poor sleep, excessive recreational screen time, alcohol use and tobacco use.Results The prevalence of excessive recreational screen time (prevalence ratios (PR)=1.06, 95% CI=1.03 to 1.11), insufficient fruit intake (PR=1.50, 95% CI=1.26 to 1.79), and alcohol (PR=4.34, 95% CI=2.82 to 6.67) and tobacco use (PR=4.05 95% CI=1.86 to 8.84) increased over the 2-year period, with alcohol use increasing more among girls (PR=2.34, 95% CI=1.19 to 4.62). …”
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