Aging-enhanced autophagy activity promotes fibrotic progression via the TGF-β2/Smad signaling pathway in trabecular meshwork cells—a new insight from POAG by Jin Han, Jun Wang, Ling Shen, Yiting Cai, Xuze Wang, Ailixiati Wumaier, Wei Chen, Wei Han

“…An in vitro aging model using chronic H2O2 treatment was established to investigate the change of fibrosis in TM cells. Additionally, we used dexamethasone-treated TM cells as a POAG model to explore the role of autophagy in fibrotic progression. …”
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Predicting ixodid tick distribution in Tamil Nadu domestic mammals using ensemble species distribution models by Ayyanar Elango, Hari Kishan Raju, Ananganallur Nagarajan Shriram, Ashwani Kumar, Manju Rahi

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Evaluation of the Mechanical Properties of Different Dental Resin-Based Materials After Submersion in Acidic Beverages by Răzvan Constantin Brânzan, Ionuț Tărăboanță, Cristina Angela Ghiorghe, Simona Stoleriu, Vlad Cârlescu, Andra Claudia Tărăboanță-Gamen, Sorin Andrian

“…<b>Conclusions</b>: The submersion of conventional nanohybrid, flowable, heavy-flow composite resins and resin-based sealants in coffee, cola and red wine solutions changes the mechanical properties (Young’s modulus of elasticity, Vickers microhardness and scratch resistance). …”
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Efferocytosis-related gene IL33 predicts prognosis and immune response and mediates proliferation and migration in vitro and in vivo of breast cancer by Xiao He, Xianjie Cheng, Zhun Zhang, Lanhui Chen, Changjun Xie, Mengjie Tang

“…Additionally, single-sample GSEA (ssGSEA) was used to examine changes in immune infiltration and enrichment. A risk prognostic model was constructed utilizing multivariable Cox regression and Least Absolute Shrinkage and Selection Operator (LASSO) analyses, and subsequently validated its predictive accuracy by stratifying patients according to the median risk score. …”
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Testicular biometrics of Murrah buffaloes in different age groups by Erly L. Carrascal-Triana, Jorge Mejía Lúquez, Divier Agudelo Gómez, Edison Julián Ramírez Toro

“…More studies are necessary to standardize the morphofunctional changes of buffaloes chronologically. …”
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Business’ Attitudes Towards Corruption in Selected Central European Countries by Nenad Vretenar, Ana Marija Filipas, Martina Briš Alić

“…In the countries where these differences are substantial, attitudes towards corruption are related to perceptions of problems arising from frequent changes in the law, problems with debt collection, and differences in views regarding the severity of bribery depending on the value of the bribe. …”
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Effective leaf rust resistance genes of wheat in Novosibirsk Province in connection with the variability of the <i>Puccinia triticina</i> population by L. P. Sochalova, N. I. Boyko, A. A. Poteshkina, V. V. Piskarev

“…The local leaf rust population has changed slightly over the years of study (the Lr18 and Lr38 genes have lost resistance), and was very different from the population before 2010.…”
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The influence of scapular orientation on the medial scapula corpus angle in snapping scapula syndrome by Brittany Percin, BS, MS4, Joseph Featherall, MD, Robert Z. Tashjian, MD, Peter N. Chalmers, MD, Christopher D. Joyce, MD, Alexander J. Mortensen, MD, Heath B. Henninger, PhD

“…Results: Scapula type commonly changed and the MSCA varied up to 104° within a subject depending on the imaging plane, regardless of location below or above the reference plane. …”
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The Effect of Prejudice and Discrimination Education Given to University Students on Gender Perception and Attitude by Neslihan Nur Pehlivan

“…In order for university students to approach men and women with an egalitarian perspective at an early age, their gender stereotypes must first decrease and their perspectives on social relations must change positively. Therefore, university education can play an important role in influencing gender perception and attitudes towards gender roles. …”
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Immune Profile Differences between IgG4-Related Diseases and Primary Sj&ouml;gren&rsquo;s Syndrome by Qin Y, Shang L, Wang Y, Feng M, Liang Z, Wang N, Gao C, Luo J

“…In addition, we compared serum parameters, immune cells, and cytokines of IgG4-RDwith mouth dryness or eye dryness with those of pSS with the same symptoms, and similar serological changes were observed. IgG4-RD patients with mouth dryness had higher IgG4 (p < 0.001) and Th cells (p = 0.016) but lower IgG1 (p = 0.009) compared to pSS with dry mouth. …”
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Efficacy of Functional Endoscopic Sinus Surgery and Impact of Chronic Lung Disease on its Outcome in Patients of Chronic Rhinosinusitis by Minakshmi Karmakar, V D Prasanna Kumar Vasamsetty, Bonapart Chowdhury

“…Post-operative follow up was done at 1week, 2 weeks, 4 weeks, 8 weeks, 3 months, 6 months, 9 months and 1year intervals for one year and assessment was done in respect to improvement of symptoms using grading scale where success is meant by complete resolution of symptoms or improvement of symptoms (score +1) and cases with no change of symptoms (score 0) or deterioration of symptoms (score -1) are said to be failures within 1 year of follow-up. …”
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Sodium Butyrate: A Multifaceted Modulator in Colorectal Cancer Therapy by Alexandra Laura Mederle, Alexandra Semenescu, George Andrei Drăghici, Cristina Adriana Dehelean, Nicolae-Valentin Vlăduț, Dragoş Vasile Nica

“…RT-PCR was used to determine changes in the expression of critical pro-apoptotic players (<i>BAX</i>, <i>CASP3</i>, <i>PUMA</i>, <i>TP53</i>), anti-apoptotic facilitators (<i>BCL</i>-2, <i>MCL-1</i>), cell division regulators (<i>PCNA</i>, <i>Ki-67</i>, <i>CDKN</i>1), and inflammation genes (<i>NF-κB</i>). …”
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Intention to vaccinate against COVID-19 and adherence to non-pharmaceutical interventions against COVID-19 prior to the second wave of the pandemic in Uganda: a cross-sectional stu... by Ambrose Talisuna, Solome Okware, Rhoda K Wanyenze, Solomon Tsebeni Wafula, Innocent B Mugume, Benjamin Sensasi, Alexander Chimbaru, Richard Kabanda, Tabley Bakyaita, Jayne Byakika-Tusiime

“…Concerns about the chances of getting COVID-19 in the future (Prevalence Ratio (PR)=1.26, 95% CI 1.06 to 1.48) and fear of severe COVID-19 infection (PR=1.20, 95% CI 1.04 to 1.38) were the strongest predictors for a definite intention, while concerns for side effects were negatively associated with vaccination intent (PR=0.75, 95% CI 0.68 to 0.83).Conclusion Behaviour change programmes need to be strengthened to promote adherence to COVID-19 preventive guidelines as vaccination is rolled out as another preventive measure. …”
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Establishing an Electrophysiological Recording Platform for Epidural Spinal Cord Stimulation in Neuropathic Pain Rats by Yang CT, Shyu BC, Lin WT, Lu KH, Lin CR, Wen YR, Chen CC

“…This study comprehensively analyzed methodology and technical challenges and pitfalls encountered during the development and implementation of this model.Materials and Methods: Employing a newly developed pUHF-SCS (± 3 V, 2 Hz pulses with 500-kHz biphasic radiofrequency sinewaves), we assessed analgesic effect and changes of evoked local field potentials (eLFPs) in the bilateral primary somatosensory and anterior cingulate cortices in the rats with or without spared nerve injury (SNI) using the platform. …”
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Determining the status of ecosystem degradation trends and their implications for ecological integrity in the southern African grassland biome by L.R. Vukeya, T.M. Mokotjomela, N. Pillay

“…The value of the southern African grassland biome as a biodiversity hotspot will be amplified by its potential to sequester carbon and contribute towards climate change mitigation. Despite this, several studies have reported alarming degradation and transformation of this biome, threatening its ecosystem functioning and services. …”
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Model Agile Scrum untuk Pengembangan Sistem Pencarian Dokumen Surat Digital Berbasis Konten Terklasifikasi dengan Ontologi by Rifiana Arief, Suryarini Widodo, Ary Bima Kurniawan, Hustinawaty Hustinawaty, Faisal Arkan

“…In the future, this system can also be developed for use by other institutions by changing the classification in accordance with the comprehension procedures. …”
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Mechanism of Bone-metastatic LUAD Cells Promoting Angiogenesis 
Through HGF/YAP Signaling Pathway by Yan DENG, Rong QIU, Xingyu LIU, Yingyang SU, Yang XUE, Yuzhen DU

“…Background and objective The early stages of tumor bone metastasis are closely associated with changes in the vascular niche of the bone microenvironment, and abnormal angiogenesis accelerates tumor metastasis and progression. …”
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Real-world study of phakic refractive lens for correction of high myopia by An-Peng Pan, Xu Shao, Yi-Ke Li, Zi-Yue Li, Qiong Yan, Wei-Yang Sun, A-Yong Yu

“…The percentage of eyes within ± 0.50 D and ± 1.00 D of target refraction was 58% and 83%, respectively. Mean MRSE changed from − 14.49 ± 4.22 D, preoperatively, to − 1.22 ± 1.26 D at 1 day (P < 0.001) and remained stable thereafter. …”
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Neural Network and Hybrid Methods in Aircraft Modeling, Identification, and Control Problems by Gaurav Dhiman, Andrew Yu. Tiumentsev, Yury V. Tiumentsev

“…These circumstances cause the problem of a rapid adjustment of the used control laws so that the control system can adapt to the mentioned changes. However, most adaptive control schemes have a model of the control object, which plays a crucial role in adjusting the control law. …”
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Effects of a nutrition education intervention on nutrition knowledge and attitude among overweight and obese primary schoolchildren: a cluster randomized controlled trial by Rusidah Selamat, Nur Azlina Abdul Aziz, Junidah Raib, Norlida Zulkafly, WNurul Ashikin W. Mohamad, Ainan Nasrina Ismail, Muhammad Yazid Jalaludin, Fuziah Md. Zain, Zahari Ishak, Abqariyah Yahya, Abdul Halim Mokhtar

“…The main outcome measures were nutrition knowledge and attitude scores. Changes of nutrition knowledge and attitude scores from follow up until end of 6 months was assessed using the mixed effect model taking into account the cluster effect. …”
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