Functional near-infrared spectroscopy for the assessment and treatment of patients with disorders of consciousness by Nan Wang, Nan Wang, Nan Wang, Yifang He, Sipeng Zhu, Dongsheng Liu, Xiaoke Chai, Xiaoke Chai, Qiheng He, Tianqing Cao, Jianghong He, Jingqi Li, Juanning Si, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Jizong Zhao, Jizong Zhao

“…In addition to assessing consciousness levels, fNIRS offers unique advantages in tracking hemodynamic changes associated with neuroregulatory treatments, including DBS and SCS. …”
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How to protect the proximal bronchial tree during stereotactic radiotherapy of ultracentral lung tumors: Lessons from MR-guided treatment by Sebastian Regnery, Efthimios Katsigiannopulos, Hin Lau, Philipp Hoegen-Saßmannshausen, Fabian Weykamp, Claudia Katharina Renkamp, Carolin Rippke, Fabian Schlüter, Sophia Albert, Jan Meis, Marietta Kirchner, Alexandra Balzer, Nicolaus Andratschke, Matthias Guckenberger, Jürgen Debus, Sebastian Klüter, Juliane Hörner-Rieber

“…Furthermore, moderate interfractional translations are observed (mean absolute translation ML: 1.3 mm, AP: 1.3 mm, SI: 1.1 mm), with an estimated 2 mm PRV margin for interfractional changes alone. Simulated non-adaptive SBRT leads to PBT overdoses in 60 % of patients (median overdosed fractions VMAT: 2.5, predicted MR-linac plans 4). …”
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uN2CpolyG-mediated p65 nuclear sequestration suppresses the NF-κB-NLRP3 pathway in neuronal intranuclear inclusion disease by Yu Shen, Kaiyan Jiang, Dandan Tan, Min Zhu, Yusen Qiu, Pencheng Huang, Wenquan Zou, Jianwen Deng, Zhaoxia Wang, Ying Xiong, Daojun Hong

“…Methods Single-cell RNA sequencing was conducted on the skin tissues of NIID patients to assess changes in the expression of genes involved in inflammatory pathways. …”
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Evaluation of bone mineral density and its influencing factors in patients infected with HIV under antiretroviral therapy by Alireza Azarboo, Mahboobeh Hemmatabadi, Noushin Fahimfar, Zahra Faghihi, SeyedAhmad SeyedAlinaghi, Nooshin Shirzad, Ladan Abbasian

“…Conclusion This study highlights the multifactorial nature of BMD changes in individuals living with HIV. By identifying correlations between metabolic, hormonal, and disease-related factors and bone health, our findings bring attention to an often-overlooked aspect of HIV management, that is patients with HIV may benefit from routine BMD screening, as it could help identify early risks of low BMD.…”
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Longitudinal exploration of cancer-related cognitive impairment in patients with newly diagnosed aggressive lymphoma: protocol for a feasibility study by Vincent Dore, Christopher C Rowe, Meinir Krishnasamy, Haryana Dhillon, Adam K Walker, Karla Gough, Priscilla Gates, Carlene Wilson, Eliza Hawkes, Yuliya Perchyonok, Janette L Vardy, Michiel de Ruiter

“…These data will inform the design of a larger-scale investigation into the patterns of cognitive change over the course of treatment and recovery, adding to an underexplored area of cancer survivorship research.Ethics and dissemination Ethical approval has been granted by Austin Health Human Rights Ethics Committee (HREC) in Victoria Australia. …”
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Pure ICL Implantation: A Novel Ophthalmic Viscosurgical Device-Free Method by Qin Qin, Lianyun Bao, Zifang He, Feifei Chen, Dandan Zhu, Si Zhang, Wenwen Zhang, Yajun Liu, Ruiying Gao, Zhenggao Xie

“…No significant difference in ECD changes within or between groups was observed (P>0.05). …”
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Proteasome inhibition enhances oncolytic reovirus therapy in multiple myeloma independently of its direct cytotoxic effects by Ada Alice Dona, Theophilus Tandoh, Lokesh Nigam, Mahmoud Singer, Enrico Caserta, Mariam Murtadha, Yinghui Zhu, Milad Moloudizargari, Preeti Sharma, Ottavio Napolitano, Janet Winchester, Arnab Chowdhury, Alex Pozhitkov, James F. Sanchez, Hawa Vahed, Guido Marcucci, Matt Coffey, Gerard Nuovo, Douglas W. Sborov, Flavia Pichiorri, Craig C Hofmeister

“…Immune fluorescence, flow cytometry, and luciferase reporter assays were used to assess NF-κB pathway activation upon RV treatments. Immune profiling changes, both ex vivo and in MM patients, were analyzed by flow cytometry and CyTOF analysis. …”
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Impacts of drought on respiratory mortality in the upper midwest United States: a population subgroup assessment by Yeongjin Gwon, Yuanyuan Ji, Jesse D Berman, Azar M Abadi, Ronald D Leeper, Jared Rennie, Jesse E Bell

“…Its frequency and intensity are expected to increase due to climate change, posing significant threats to human health. …”
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Patterns of general and abdominal obesity and their association with hypertension control in the iranian hypertensive population: insights from a nationwide study by Fataneh Esmaeili, Keyvan Karimi, Samaneh Akbarpour, Mohammadreza Naderian, Shirin Djalalinia, Ozra Tabatabaei-Malazy, Ali Golestani, Nazila Rezaei

“…These findings underscore the need for healthcare providers to implement targeted interventions promoting healthy lifestyle changes to mitigate these risk factors and improve HTN management.…”
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Assessment of Air Pollution and Lagged Meteorological Effects in an Urban Residential Area of Kenitra City, Morocco by Mustapha Zghaid, Abdelfettah Benchrif, Mounia Tahri, Amine Arfaoui, Malika Elouardi, Mohamed Derdaki, Ali Quyou, Moulay Laarbi Ouahidi

“…CO is sensitive to temperature and pressure changes, with delayed impacts, while O₃ formation was primarily influenced by temperature and wind speed, reflecting complex photochemical processes. …”
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Characterization of the genomic landscape of canine diffuse large B-cell lymphoma reveals recurrent H3K27M mutations linked to progression-free survival by Anna Darlene van der Heiden, Raphaela Pensch, Sophie Agger, Heather L. Gardner, William Hendricks, Victoria Zismann, Shukmei Wong, Natalia Briones, Bryce Turner, Karin Forsberg-Nilsson, Cheryl London, Kerstin Lindblad-Toh, Maja Louise Arendt

“…While previous studies on canine DLBCL (cDLBCL) have significantly advanced our understanding of the disease, the majority of this research has relied on whole-exome sequencing, which is limited in its ability to detect copy number aberrations and other genomic changes beyond coding regions. Furthermore, many of these studies lack sufficient clinical follow-up data, making it difficult to draw meaningful associations between genetic variants and patient outcomes. …”
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Detection Rate of Helicobacter Pylori Infection and Atrophic Gastritis Using Serological Markers “GastroPanel®” Among Employees of the National Medical Research Radiological Centre... by A. D. Kaprin, N. S. Sergeeva, S. S. Pirogov, I. I. Alentov, O. К. Yutsevich, V. I. Ryabtseva, G. F. Minibaeva, N. V. Marshutina, T. А. Karmakova

“…“GastroPanel®” confirmed its high significance in identifying H. pylori infection and precancerous atrophic changes in the gastric mucosa. Regarding the occupational risks of infection among medical workers, we consider it advisable to conduct such screening without selecting an asymptomatic population.…”
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Trends in infections detected in women with cervicitis over a decade by Lenka A. Vodstrcil, Lenka A. Vodstrcil, Lenka A. Vodstrcil, Erica L. Plummer, Erica L. Plummer, Thuy Vy Nguyen, Thuy Vy Nguyen, Christopher K. Fairley, Christopher K. Fairley, Eric P. F. Chow, Eric P. F. Chow, Eric P. F. Chow, Tiffany R. Phillips, Tiffany R. Phillips, Catriona S. Bradshaw, Catriona S. Bradshaw, Catriona S. Bradshaw

“…The proportion of cases tested for BV (90%) did not change overtime, but detection increased from 32% to 45% (Ptrend < 0.001). …”
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Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC by Xiyu Song, Xiyu Song, Xiyu Song, Jianhua Jiao, Jianhua Jiao, Jiayang Qin, Wei Zhang, Weijun Qin, Weijun Qin, Shuaijun Ma, Shuaijun Ma

“…The overall percentage of activated MCs in ccRCC tissues did not change significantly but shifted toward a more activated subpopulation (VEGFA+ MCs), with a concomitant decrease in proliferative MCs (TNF+ MCs) and resting MCs. …”
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Empirical estimation of saturated soil-paste electrical conductivity in the EU using pedotransfer functions and Quantile Regression Forests: A mapping approach based on LUCAS topso... by Calogero Schillaci, Simone Scarpa, Felipe Yunta, Aldo Lipani, Fernando Visconti, Gábor Szatmári, Kitti Balog, Triven Koganti, Mogens Greve, Giulia Bondi, Georgios Kargas, Paraskevi Londra, Fuat Kaya, Giuseppe Lo Papa, Panos Panagos, Luca Montanarella, Arwyn Jones

“…EC is considered a proxy of soil salinity and other soil characteristics, whose monitoring is much needed in the context of climate change, increasing irrigation in agricultural areas and sea level rise. …”
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Effects of Brackish Water with Different Sodium-Potassium Ratios on Soil Water-Salt Characteristics and Winter Wheat Growth by GAO Weiqiang, ZHANG Tibin, TONG Jiankang, LIU Zhenyuan, LIANG Qing, KUANG Yuxin, CHENG Yu, FENG Hao

“…[Conclusion] In summary, irrigation using 4 dS/m brackish water changed the original water-salt characteristics of the soil, caused salts to accumulate in the soil and promoted winter wheat growth in the short term. …”
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Immunomodulatory and anti-inflammatory potential of botanicals bioactive product (PHYTO AX'CELL™) for an improvement of the well-being of laying hens at the peak of production by Alessandro Guerrini, Roberta Salaroli, Augusta Zannoni, Giancarlo Avallone, Francesca Leone, Valentina Serra, Giulia Quaglia, Francesca del Zozzo, Thibaut Chabrillat, Claire Carlu, Caterina Lupini, Doriana Eurosia Angela Tedesco

“…A T4, significant reduction in duodenal and rectal pH was observed in the treated group (P < 0.05), without intestinal inflammation score changes, body weight, serum biochemistry, interleukin levels, and infectious bronchitis virus titers (P > 0.05). …”
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Efficacy and cost-effectiveness of an ACT and compassion-based intervention for women with breast cancer: study protocol of two randomised controlled trials {1} by Inês A. Trindade, Andreia Soares, David Skvarc, Diogo Carreiras, Joana Pereira, Óscar Lourenço, Filipa Sampaio, Bruno de Sousa, Teresa C. Martins, Paula Boaventura, Joana Marta-Simões, Mind Project Team, Helena Moreira

“…Analyses of moderators and mediators of change will also be performed. Discussion These trials examine the efficacy and cost-effectiveness of an integrative ACT and compassion-based intervention tailored for women with breast cancer. …”
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NLRP3 activation maintains intestinal epithelial barrier and reduces liver injury in alcoholic liver disease mice by Shi‐Qing Li, Ya‐Ru Wang, Zhong‐Liang Xie, Yan Wang, Zi‐Han Feng, Jian‐Hao Xu, Bing Yuan, Yi‐Tong Zhang, Guan Yang, Jing‐Lin Wang, Yuan Yuan

“…Concurrently, we examined the changes in inflammation and liver damage in the ileum of ALD and healthy mice following foodborne infection with V. vulnificus. …”
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sST2 as a New Biomarker of Chronic Kidney Disease-Induced Cardiac Remodeling: Impact on Risk Prediction by Maëlle Plawecki, Marion Morena, Nils Kuster, Leila Chenine, Hélène Leray-Moragues, Bernard Jover, Pierre Fesler, Manuela Lotierzo, Anne-Marie Dupuy, Kada Klouche, Jean-Paul Cristol

“…Regarding echocardiogram data, sST2 was correlated with left ventricular mass index (ρ=0.16, p=0.02), left atrial diameter (ρ=0.14, p=0.04), and volume index (ρ=0.13, p=0.05). sST2 alone did not change risk prediction of death and/or CV events compared to natriuretic peptides. …”
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