The effects of magnitude of calcium decline at the onset of lactation on serotonin dynamics and the serotonin-calcium axis by M.K. Connelly, R.M. Rodney, J. Kuehnl, J.P.N. Andrade, F. Sonnewend Andrade, S. Henschel, E. Block, I.J. Lean, L.L. Hernandez

“…Recently emphasis was placed on understanding the profile and dynamics of blood Ca and serotonin in the peripartal cow in response to this change using a randomized 2 × 2 factorial design. …”
Get full text

Exhaustion of CD8pos central memory regulatory T cell differentiation is involved in renal allograft rejection by Florian Kälble, Jonas Leonhard, Jonas Leonhard, Martin Zeier, Oliver Zivanovic, Matthias Schaier, Andrea Steinborn

“…We were investigating whether changed differentiation of CCR7posCD45RAposCD31pos recent thymic emigrant (RTE) cells via CD45RAnegCD31pos memory (CD31pos memory) cells (pathway 1), via direct proliferation (pathway 2), or via CCR7posCD45RA+CD31neg resting mature naïve (MN) cells (pathway 3) into CD45RAnegCD31neg memory (CD31neg memory) cells affects the CD8pos Treg/Tresp ratio or identifies a CD8pos Treg/Tresp subset that predicts or confirms renal allograft rejection.ResultsWe found that RTE Treg differentiation via pathway 1 was age-independently increased in KTR, who developed graft rejection during the follow-up period, leading to abundant MN Treg and central memory Treg (CM Treg) production and favoring a strongly increased CD8pos Treg/Tresp ratio. …”
Get full text

The Magnitude of Salt Intake Behaviors and Its Predictors among Saqez Urban Population of Kurdistan District in Iran: A Cross-Sectional Study by Kolsom Khoram, Mohammad Asghari-Jafarabadi, Mehrangiz Ebrahimi-Mamagani, Behjat Shokrvash, Maral Hariri-Akbari

“…In parallel with the development and change of people’s lifestyles, new approaches (legal and services) for salt control based on the support of media and social media were expected.…”
Get full text

Effect of Tea Polyphenols, α-Lipoic Acid and Their Joint Use on the Antioxidant and Lipid Metabolism Performance of Hybrid Grouper (♀Epinephelus fuscoguttatus × ♂E. lanceolatu) Fed... by Xiangxiang Suo, Xiaobo Yan, Beiping Tan, Simiao Pan, Tao Li, Hao Liu, Weibin Huang, Shuang Zhang, Yuanzhi Yang, Xiaohui Dong

“…The relative expressions of lipoprotein lipase (lpl) and peroxisome proliferators-activated receptors-α (pparα) genes related to lipid catabolism were increased, among which the OL group had the most significant change (P<0.05). (7) According to the 7-day challenge test of Vibrio alginolyticus, the OL group had the highest survival rate. …”
Get full text

PET Study of Sphingosine-1-phosphate Receptor 1 Expression in Response to S. aureus Infection by Hao Jiang, Jiwei Gu, Haiyang Zhao, Sumit Joshi, Joel S. Perlmutter, Robert J. Gropler, Robyn S. Klein, Tammie L. S. Benzinger, Zhude Tu

“…A rodent local muscle bacterial infection model was developed by injecting S. aureus to the lower hind limb of Balb/c mice. The changes of S1PR1 expression in response to bacterial infection and blocking treatment were assessed using ex vivo biodistribution and in vivo positron emission tomography (PET) after intravenous injection of an S1PR1-specific radiotracer [18F]TZ4877. …”
Get full text

Investigation of deflections and natural vibration frequencies of circular isotropic plates of variable thickness according to the law of square parabola with thickening to the sup... by A. V. Turkov, S. I. Poleshko

“…Based on the theoretical data obtained, it is possible to diagnose defects (change in the design scheme, destruction, reduction in the thickness of the plate as a result of corrosion, etc.) based on the results of comparison and analysis of theoretical and experimentally measured natural vibration frequencies and (or) maximum deflections in the center of the plate.Materials and methods. …”
Get full text

Effectiveness of eHealth literacy interventions: a systematic review and meta-analysis of experimental studies by Chiara Barbati, Elvira Maranesi, Cinzia Giammarchi, Matteo Lenge, Manila Bonciani, Elisa Barbi, Giacomo Pietro Vigezzi, Mauro Dragoni, Tania Bailoni, Anna Odone, Roberta Bevilacqua

“…We performed a random-effects model meta-analysis comparing changes in eHL levels before and after the interventions, and between the intervention and control groups. …”
Get full text

Pharmacokinetics of Hydrogen During Hydrogen-Saturated Saline Infusion in Pigs by Masaki Shibuya, Masafumi Fujinaka, Mako Yonezawa, Natsumi Nishimura, Hitoshi Uchinoumi, Hiroshi Sunahara, Kenji Tani, Eiji Kobayashi, Motoaki Sano

“…<b>Results</b>: It was confirmed that hydrogen can be safely mixed under pressure into intravenous solutions (pharmaceutical products) without the contamination of foreign substances by using a needle-less vial access cannula. No change in the PH or composition of the solution was observed due to hydrogen filling. …”
Get full text

Increased positive tree species mixture effects on the abundance and richness of Collembola with stand development in Canadian boreal forests by Yakun Zhang, Sai Peng, Zilong Ma, Chen Chen, Bilei Gao, Xinli Chen, Han Y.H. Chen

Get full text

Dietary effects of protected fat, soybean meal, and heat-treated soybean meal on performance, physiological parameters, and behavioral measurements of early-fattening Hanwoo steers... by Jun Sik Woo, Sun Sik Jang, Jeong Hoon Kim, Hong Gu Lee, Keun Kyu Park

“…As THI increased, rectal temperature and all blood parameters increased, while blood glucose levels decreased (p<0.05). Behavioral changes during 1st period compared to 3rd included decreases in lying (24%), walking (48%), and eating (40%), and increases in total standing (50%) and drinking (43%) (p<0.05). …”
Get full text

Epidemiological trends and age-period-cohort effects on ischemic stroke burden across the BRICS-plus from 1992 to 2021 by Fangqun Cheng, Peiyu Cheng, Shudong Xie, Hailing Wang, Ying Tang, Ying Liu, Zhuo Xiao, Guixiang Zhang, Guangxiong Yuan, Ke Wang, Can Feng, Ying Zhou, Hong Xia, Yan Wang, Yuhang Wu

“…Methods Data on the number, all-age rate, age-standardized rate, and relative change in ischemic stroke disability-adjusted life years (DALYs) from 1992 to 2021 within BRICS-plus were obtained from the Global Burden of Disease Study (GBD) 2021. …”
Get full text

Evaluation of the efficacy of bromfenac sodium in the treatment of dry eye disease by I.A. Loskutov, E.F. Semashko, E.N. Khomyakova, E.I. Makukha, N.E. Kostina

“…After 4 weeks of treatment, 41% of patients were symptom free. All changes during the study were significant (p&lt;0.05). …”
Get full text

Arctiin Protects Chondrocytes from Interleukin-1β-Induced Inflammation and Apoptosis by RNA Sequence In vivo and In vitro by Yong-Jia Song, Jia-Min Bao, Zeng-Qiao Zhang, Yun-Xiang Hai, Hao-Nan Wen, Tian-Jun Zhai, Wei Feng, Min Song

“…Techniques such as biochemical assays, Enzyme-linked immunosorbent assay, quantitative real-time polymerase chain reaction (qRT-PCR), Western blotting, and immunofluorescence labeling were employed to detect changes in nitric oxide (NO), lactate dehydrogenase (LDH), inflammatory markers, and components of the cartilage matrix in chondrocytes. …”
Get full text

Clinical observation on holographic meridian scraping therapy combined with auricular bloodletting therapy in treating primary hypertension in the elderly (全息经络刮痧联合耳尖放血疗法治疗老年高血压病临床... by ZHEN Chao (郑超), LI Ning (李宁), CAO Hongjing (曹红京)

“…On the basis of drug therapy and routine health education, the control group received auricular bloodletting therapy, while the observation group received holographic meridian scraping therapy combined with auricular bloodletting therapy. The changes in blood pressure and Traditional Chinese Medicine (TCM) syndrome score were observed, and the intervention effect was evaluated by comparing the improvement of blood pressure and clinical symptoms. …”
Get full text

Bioinformatics analysis of ferroptosis-related hub genes and immunoinfiltration in myocardial ischemia/reperfusion following heart transplantation by Yuxi Zhang, Qiao Tang, Jiahui Cui, Yanan Li, Heng Xu, Zhen Qiu, Shaoqing Lei, Rui Xue, Qian Sun, Zhongyuan Xia

“…Immunoinfiltration analysis showed that 16 of 22 immune cells changed, and the immune score of heart transplantation with I/R was higher than that without I/R. …”
Get full text

Salidroside promotes pro-angiogenesis and repair of blood brain barrier via Notch/ITGB1 signal path in CSVD Model by Tu Zhilan, Zhang Zengyu, Jin Pengpeng, Yang Hualan, Li Chao, Xi Yan, Guo Zimin, Hou Shuangxing, Li Weiwei

Get full text

The analysis of the notions of Russian school principals about digital transformation by A. A. Deryabin, I. E. Boytsov, A. A. Popov, P. D. Rabinovich, K. E. Zavedensky, I. S. Tsarkov

“…The research findings demonstrated the significant imbalance in the frequency of responses: the most frequent answers belong to the “Infrastructure” category, while the least frequent ones belong to the categories of pedagogical aspects of digital transformation affecting changes in the educational content and methods for assessing educational outcomes. …”
Get full text

Human Serum Albumin and Human Serum Albumin Nanoparticles as Carriers of 10-(2′-Pyrimidyl)-3,6-diazaphenothiazine: In Vitro Spectroscopic Studies by Aleksandra Owczarzy, Karolina Kulig, Beata Morak-Młodawska, Małgorzata Jeleń, Tammam Muhammetoglu, Wojciech Rogóż, Małgorzata Maciążek-Jurczyk

“…High encapsulation efficiency of 10-Pyr-3,6-DAPT into the HSA-NPs was obtained, and the changes in albumin secondary structure due to the presence of 10-Pyr-3,6-DAPT were registered. …”
Get full text

Development and Validation of an UHPLC-MS/MS Method for Quantification of DMAG in Rat Plasma and Its Application in a Preliminary Pharmacokinetic Study in Thrombocytopenia Rats by Yan Li, Yuqing Wang, Zhiqiang Zhao, Yunxia Li, Cheng Peng, Jianming Wu

“…The intraday RSD and interday RSD were between 3.31% and 13.19%, accuracy RE was ≤6.69%, and stability RSD changes were 3.38%–8.78%. As for intragastric administration, with shortened Tmax (3.00 vs. 2.16 h), Cmax (25.67 vs. 35.38 ng/mL) was added for a 2 mg/kg dose after the establishment of the thrombocytopenia rat model. …”
Get full text

Physiological and image-based phenotyping assessment of waterlogging responses of three kiwifruit rootstocks and grafting combinations by Maria Calabritto, Alba N. Mininni, Roberto Di Biase, Angelo Petrozza, Stephan Summerer, Francesco Cellini, Bartolomeo Dichio

“…The aim of the present study was to evaluate morpho-physiological changes in kiwifruit rootstocks and grafting combinations under short-term waterlogging stress.MethodsA pot trial was conducted at the ALSIA PhenoLab, part of the Phen-Italy infrastructures, using non-destructive RGB and NIR image-based analysis and physiological measurements to identify waterlogging stress indicators and more tolerant genotypes. …”
Get full text