Targeting Viperin prevents coxsackievirus B3-induced acute heart failure by Yukang Yuan, Liping Qian, Ying Miao, Qun Cui, Ting Cao, Yong Yu, Tingting Zhang, Qian Zhao, Renxia Zhang, Tengfei Ren, Yibo Zuo, Qian Du, Caixia Qiao, Qiuyu Wu, Zhijin Zheng, Minqi Li, Y. Eugene Chinn, Wei Xu, Tianqing Peng, Ruizhen Chen, Sidong Xiong, Hui Zheng

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Structural insights into ligand recognition and activation of human purinergic receptor P2Y14 by Quanchang Gu, Zhenyu Lv, Tianxin Wang, Wenqin Tang, Xuzhen Guo, Xiangling Huang, Fahui Li, Jiangyun Wang

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Molecular mechanisms of urate transport by the native human URAT1 and its inhibition by anti-gout drugs by Canrong Wu, Chao Zhang, Sanshan Jin, James Jiqi Wang, Antao Dai, Jiuyin Xu, Heng Zhang, Xuemei Yang, Xinheng He, Qingning Yuan, Wen Hu, Youwei Xu, Mingwei Wang, Yi Jiang, Dehua Yang, H. Eric Xu

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Structural mechanisms of human sodium-coupled high-affinity choline transporter CHT1 by Jing Xue, Hongwen Chen, Yong Wang, Youxing Jiang

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Single-cell and spatial proteo-transcriptomic profiling reveals immune infiltration heterogeneity associated with neuroendocrine features in small cell lung cancer by Ying Jin, Yuefeng Wu, Alexandre Reuben, Liang Zhu, Carl M. Gay, Qingzhe Wu, Xintong Zhou, Haomin Mo, Qi Zheng, Junyu Ren, Zhaoyuan Fang, Teng Peng, Nan Wang, Liang Ma, Lungevity PANSHI Initiative Consortium, Yun Fan, Hai Song, Jianjun Zhang, Ming Chen

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Unveiling potential threats: backdoor attacks in single-cell pre-trained models by Sicheng Feng, Siyu Li, Luonan Chen, Shengquan Chen

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Structural insight into PIF6-mediated red light signal transduction of plant phytochrome B by Hanli Jia, Zeyuan Guan, Junya Ding, Xiaoyu Wang, Dingfang Tian, Yan Zhu, Delin Zhang, Zhu Liu, Ling Ma, Ping Yin

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AR to GR switch modulates differential TDO2-Kyn-AhR signalling to promote the survival and recurrence of treatment-induced dormant cells in prostate cancer by Sangsang Li, Yifan Zhang, Maoxing Luo, Weiwei Zhou, Yitong Chen, Dinglan Wu, Qiang Wei, Yan Chang, Hailiang Hu

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Transgenerational inheritance of diabetes susceptibility in male offspring with maternal androgen exposure by Yuqing Zhang, Shourui Hu, Shan Han, Congcong Liu, Xiaofan Liang, Yuxuan Li, Zongxuan Lin, Yiming Qin, Chunxuan Geng, Yue Liu, Linlin Cui, Jingmei Hu, Changming Zhang, Zhao Wang, Xin Liu, Jinlong Ma, Zi-Jiang Chen, Han Zhao

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TMEM41B is an endoplasmic reticulum Ca2+ release channel maintaining naive T cell quiescence and responsiveness by Yuying Ma, Yi Wang, Xiaocui Zhao, Gang Jin, Jing Xu, Zhuoyang Li, Na Yin, Zhaobing Gao, Bingqing Xia, Min Peng

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SGF29 nuclear condensates reinforce cellular aging by Kaowen Yan, Qianzhao Ji, Dongxin Zhao, Mingheng Li, Xiaoyan Sun, Zehua Wang, Xiaoqian Liu, Zunpeng Liu, Hongyu Li, Yingjie Ding, Si Wang, Juan Carlos Izpisua Belmonte, Jing Qu, Weiqi Zhang, Guang-Hui Liu

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The induced-fit and catalytic mechanisms of human G6PC1 by Qihao Chen, Yuhang Wang, Renjie Li, Qinru Bai, Yan Zhao

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Structural basis for allosteric agonism of human α7 nicotinic acetylcholine receptors by Sanling Liu, Yining Zheng, Haopeng Chen, Xin Li, Qipeng Yan, Wenjun Mu, Yaning Fu, Huan Chen, Hongwei Hou, Lei Liu, Changlin Tian

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Spatially resolved C1QC+ macrophage-CD4+ T cell niche in colorectal cancer microenvironment: implications for immunotherapy response by Hangyu Zhang, Libing Hong, Zhen Dong, Shan Xin, Bo Lin, Jinlin Cheng, Weihong Tian, Bin Li, Jing Wang, Xiaoyan Liu, Chuan Liu, Yuzhi Jin, Yanzhi Feng, Ge Su, Xuqi Sun, Qiqi Liu, Xiaomeng Dai, Yang Gao, Zhou Tong, Lulu Liu, Xudong Zhu, Yi Zheng, Peng Zhao, Tiannan Guo, Weijia Fang, Xuanwen Bao

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Characterization of the landscape of the intratumoral microbiota reveals that Streptococcus anginosus increases the risk of gastric cancer initiation and progression by Li Yuan, Libin Pan, Yunzhe Wang, Jing Zhao, Luo Fang, Ying Zhou, Ruihong Xia, Yubo Ma, Zhengchen Jiang, Zhiyuan Xu, Can Hu, Yanan Wang, Shengjie Zhang, Bo Zhang, Haiying Ding, Mengxuan Chen, Haibo Cheng, Ajay Goel, Zhao Zhang, Xiangdong Cheng

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Transport and inhibition mechanisms of human creatine transporter by Jiahui Chen, Yimin Zhang, Nanhao Chen, Jingpeng Ge, Jie Yu

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Structure of small HBV surface antigen reveals mechanism of dimer formation by Xiao He, Yunlu Kang, Weiyu Tao, Jiaxuan Xu, Xiaoyu Liu, Lei Chen

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Decoding and reprogramming of the biosynthetic networks of mushroom-derived bioactive type II ganoderic acids in yeast by Qin Wang, Ye Li, Shunhan Zhang, Wei Yuan, Zeqian Du, Ting Shi, Zhao Chang, Xingye Zhai, Yinhua Lu, Meng Wang, Juan Guo, Jian-Jiang Zhong, Han Xiao

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A tumor-secreted protein utilizes glucagon release to cause host wasting by Guangming Ding, Yingge Li, Chen Cheng, Kai Tan, Yifei Deng, Huiwen Pang, Zhongyuan Wang, Peixuan Dang, Xing Wu, Elisabeth Rushworth, Yufeng Yuan, Zhiyong Yang, Wei Song

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Integrated proteogenomic characterization of ampullary adenocarcinoma by Qiao Zhang, Xiaomeng Xu, Dongxian Jiang, Yunzhi Wang, Haixing Wang, Jiajun Zhu, Shaoshuai Tang, Ronghua Wang, Shuang Zhao, Kai Li, Jinwen Feng, Hang Xiang, Zhenmei Yao, Ning Xu, Rundong Fang, Wenjia Guo, Yu Liu, Yingyong Hou, Chen Ding

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