Understanding Epistatic Interactions between Genes Targeted by Non-coding Regulatory Elements in Complex Diseases by Min Kyung Sung, Hyoeun Bang, Jung Kyoon Choi

“…Accordingly, to identify the genes affected by the SNPs, we employed whole-genome multiple-cell-type enhancer data which discovered using DNase I profiles and Cap Analysis Gene Expression (CAGE). Assigned genes were significantly enriched in known disease associated gene sets, which were explored based on the literature, suggesting that this approach is useful for detecting relevant affected genes. …”
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