A Fatal Case of Nafcillin-Induced Hepatotoxicity: A Case Report and the Literature Review by Mian Bilal Alam, Amin Kadoura, Magesh Sathaiah

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Anesthetic Isoflurane Posttreatment Attenuates Experimental Lung Injury by Inhibiting Inflammation and Apoptosis by Jun-tang Li, Hui Wang, Wei Li, Li-feng Wang, Li-chao Hou, Jing-lan Mu, Xin Liu, Hui-juan Chen, Ke-lang Xie, Nan-lin Li, Chun-fang Gao

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Inhibition of platelet activation alleviates diabetes-associated cognitive dysfunction via attenuating blood-brain barrier injury by Fuxing Xu, Juan Hu, Xuying Li, Lan Yang, Shiqiu Jiang, Tao Jiang, Bo Cheng, Hailiang Du, Ruiduo Wang, Yingying Deng, Wei Gao, Yansong Li, Yaomin Zhu

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Effect of diabetes mellitus on levels of insulin-like growth factors and their carrier proteins in Guerin’s carcinoma and it’s perifocal tissue in rats by E. M. Frantsiyants, V. A. Bandovkina, I. V. Kaplieva, E. I. Surikova, I. V. Neskubina, Yu. A. Pogorelova, N. D. Cheryarina, P. S. Kachesova, L. A. Nemashkalova

“…Diabetes mellitus (DM) is considered an independent risk factor for higher cancer incidence and death rates. The system of insulin-like growth factors and their carrier proteins (IGF and IGFBP) and hyperglycemia create favorable conditions for the proliferation and metastasis of cancer cells.Materials and methods. …”
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The Use of Machine Learning to Create a Risk Score to Predict Survival in Patients with Hepatocellular Carcinoma: A TCGA Cohort Analysis by Samer Tohme, Hamza O Yazdani, Amaan Rahman, Sanah Handu, Sidrah Khan, Tanner Wilson, David A Geller, Richard L Simmons, Michele Molinari, Christof Kaltenmeier

“…Hepatocellular carcinoma (HCC) accounts for approximately 90% of primary liver malignancies and is currently the fourth most common cause of cancer-related death worldwide. Due to varying underlying etiologies, the prognosis of HCC differs greatly among patients. …”
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Impact of multimorbidity and complex multimorbidity on mortality among older Australians aged 45 years and over: a large population-based record linkage study by Alamgir Kabir, An Tran, Sameera Ansari, Damian P Conway, Margo Barr

“…During the 8-year follow-up, there were 25 891 deaths. Cancer (34.7%) was the most prevalent chronic condition and the cardiovascular system (50.9%) was the body system most affected by a chronic condition. …”
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Understanding road accident injury dynamics in Iran: a growth mixture modelling perspective by Ziba Zarrin, Kamran Gholamizadeh, Elaheh Talebi-Ghane, Erfan Ayubi, Omid Hamidi

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Calcium hydroxide nanoparticles induce cell death, genomic instability, oxidative stress and apoptotic gene dysregulation on human HepG2 cells by Hanan R. H. Mohamed, Esraa H. Ibrahim, Shahd E. E. Shaheen, Nesma O. E. Hussein, Ayman Diab, Gehan Safwat

“…However, limited information exists regarding their effects on genomic DNA integrity and their potential to induce apoptosis in normal and cancerous human cell lines. This study thus aimed to evaluate the impact of Ca(OH)2NPs on cell viability, genomic DNA integrity, and oxidative stress induction in human normal skin fibroblasts (HSF) and cancerous hepatic (HepG2) cells. …”
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A Case of Nivolumab-Induced Severe Mononeuropathy Multiplex and Rhabdomyolysis by Katsuya Sakai, Hitoshi Mochizuki, Kosuke Mochida, Kazutaka Shiomi, Masahiro Amano, Masamitsu Nakazato

“…Nivolumab, an immune checkpoint inhibitor, is used for the treatment of advanced melanoma and other cancers and causes various immune-related adverse events (irAEs). …”
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NF-κB, JNK, and TLR Signaling Pathways in Hepatocarcinogenesis by Shin Maeda

“…Hepatocellular carcinoma (HCC) is the third largest cause of cancer deaths worldwide. The role of molecular changes in HCC have been used to identify prognostic markers and chemopreventive or therapeutic targets. …”
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Otyłość - ważny problem zdrowotny by Grażyna Nowicka

“…Overweight and obesity generally are caused by unhealthy eating patterns and a lack of physical activity. …”
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Commensalism of Fusobacterium nucleatum - The dilemma by Sangeeta Nayak, Nishmitha D. Shetty, Deepa G. Kamath

“…This bacterium can enter the blood circulation as a result of periodontal infection. It could cause numerous conditions such as halitosis, dental pulp infection, oral cancer, and systemic diseases. …”
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An Unusual Case: Salmonella UTI and Orchitis in HIV Patient by Sabrina Arshed, Hongxiu Luo, John Middleton, Abdalla Yousif

“…Salmonellosis is a major cause of gastroenteritis in the United States; however, nontyphoidal strains of Salmonella have also been known to cause urinary tract infections, usually transmitted via the fecal-urethral route. …”
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Intrinsic p53 activation restricts gammaherpesvirus driven germinal center B cell expansion during latency establishment by Shana M. Owens, Jeffrey M. Sifford, Gang Li, Steven J. Murdock, Eduardo Salinas, Darby Oldenburg, Debopam Ghosh, Jason S. Stumhofer, Intawat Nookaew, Mark Manzano, J. Craig Forrest

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The Function of Necroptosis and Its Treatment Target in IBD by Francis Atim Akanyibah, Yi Zhu, Tao Jin, Dickson Kofi Wiredu Ocansey, Fei Mao, Wei Qiu

“…Molecules involved in necroptosis, however, exhibit different expression levels in IBD and its associated colorectal cancer. Multiple studies have shown that inhibiting these molecules alleviates necroptosis-induced IBD. …”
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Evaluation of transcriptomic changes after photobiomodulation in spinal cord injury by Andrew R. Stevens, Mohammed Hadis, Hannah Alldrit, Michael R. Milward, Valentina Di Pietro, Deena M. A. Gendoo, Antonio Belli, William Palin, David J. Davies, Zubair Ahmed

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Home Respiratory Polygraphy to Detect Obstructive Sleep Apnea Syndrome after Supracricoid Partial Laryngectomy by Rosa Hernández-Sandemetrio, Natsuki Oishi, Tomás Chavero, Rafael Navarro, Isabel López, Enrique Zapater

“… Introduction Supracricoid partial laryngectomy is a surgical treatment for advanced laryngeal cancer which is implemented to preserve organ function, but it may cause obstructive sleep apnea syndrome (OSAS) due to anatomical changes after surgery that may be neglected by clinicians.…”
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Human Papillomavirus, Human Immunodeficiency Virus, and Oral Microbiota Interplay in Nigerian Youth (HOMINY): A Prospective Cohort Study Protocol by Jia Liu, Esosa Osagie, Paul Akhigbe, Nosakhare Idemudia, Ozoemene Obuekwe, Ruxton Adebiyi, Nicolas Schlecht, Yana Bromberg, Fidelis E Eki-Udoko, Nosayaba Osazuwa-Peters, Modupe Oluseun Coker

“…Introduction Persistent oral infections with high-risk human papillomavirus (HR-HPV) are a potential cause of most oropharyngeal cancers (OPCs). Oral HR-HPV infection and persistence are significantly higher in people living with HIV (PLWH). …”
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Health risk assessment and microplastic pollution in streams through accumulation and interaction by heavy metals by A.M. Sabilillah, F.R. Palupi, B.K. Adji, A.P. Nugroho

“…However, little is known about the cumulative danger caused by the association of the microplastic and heavy metals. …”
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L-shaped association of body mass index with prognosis in individuals with sepsis: a multicenter cohort study by Kunping Cui, Xiangnan Teng, Wei liu, Xiaoxiao Zhao, Shanling Xu, Lang Bai

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