The effect of blue-blocking intraocular lenses on circadian biological rhythm: protocol for a randomised controlled trial (CLOCK-IOL colour study) by Taiji Hasegawa, Kenji Obayashi, Kimie Miyata, Tetsuo Ueda, Norio Kurumatani, Keigo Saeki, Nahoko Ogata, Hiroki Tsujinaka, Mariko Yamashita, Tomo Nishi, Nobuhiro Tone, Naonori Masuda, Yutarou Mizusawa, Masahiro Okamoto, Shinji Maruoka, Masashi Kojima, Toyoaki Matsuura

“…Circadian misalignment is associated with the increased risk of sleep disturbance, obesity, diabetes mellitus, depression, ischaemic heart disease, stroke and cancer. Meanwhile, blue light causes photochemical damage to the retina, and may be associated with age-related macular degeneration (AMD). …”
Get full text

Diagnostic investigation, intervention, and outcome for post-subtotal gastrectomy patients who present with jaundice by Duan Wang, Duan Wang, Liang Zhu, Fanyi Kong, Fanyi Kong, Yingyu Pan, Yingyu Pan, Wei Liu, Xuan Wang, Weidong Pan, Jian Cao, Qiang Xu, Dong Wu, Dong Wu, Dong Wu

“…Percutaneous transhepatic cholangial drainage was applied more frequently than ERCP and surgery (69.4% vs. 25.0% vs. 5.5%), and there was no significant difference concerning technical and clini-cal success rate and complication.ConclusionGastric cancer recurrence and newly-developed pancreaticobiliary malignancies were the main causes of obstructive jaundice in patients who had subtotal gastrectomy. …”
Get full text

A ketogenic diet regulates microglial activation to treat drug addiction by Jie Ji, Yi Tang

Get full text

Tocilizumab Controls Paraneoplastic Inflammatory Syndrome but Does Not Suppress Tumor Growth of Angiomatoid Fibrous Histiocytoma by Hideaki Sabe, Akitomo Inoue, Shigenori Nagata, Yoshinori Imura, Toru Wakamatsu, Satoshi Takenaka, Hironari Tamiya

Get full text

Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients by Krista A. Delviks-Frankenberry, Chawaree Chaipan, Rachel Bagni, Kathleen Wyvill, Robert Yarchoan, Vinay K. Pathak

“…Xenotropic murine leukemia virus-related virus (XMRV) is a gammaretrovirus reported to be associated with human prostate cancer and chronic fatigue syndrome. Since retroviruses cause various cancers, and XMRV replication might be facilitated by HIV-1 co-infection, we asked whether certain patients with HIV-associated lymphomas are infected with XMRV. …”
Get full text

Helicobacter pylori Oncogenicity: Mechanism, Prevention, and Risk Factors by Muzaheed

“…Helicobacter pylori (H. pylori) is the most common cause of gastric ulcer; however, its association with gastric cancer has been proved through a variety of studies. …”
Get full text

From Global Insights to National Impact: Advancing Cardio-Oncology in Iraq by Mustafa H. Ajlan, Hasan A. Farhan, Zainab A. Dakhil

“… Cancer remains a leading cause of mortality and morbidity worldwide. …”
Get full text

Implications of Therapy-Induced Selective Autophagy on Tumor Metabolism and Survival by Luke R. K. Hughson, Vincent I. Poon, Jaeline E. Spowart, Julian J. Lum

“…Targeting these metabolic irregularities represents a promising approach to improve clinical responsiveness to cancer treatments given the inherently elevated metabolic demands of many tumor types. …”
Get full text

Phase 1 Trial of Autologous Bone Marrow Stem Cell Transplantation in Patients with Spinal Cord Injury by Zurab Kakabadze, Nickolas Kipshidze, Konstantine Mardaleishvili, Gocha Chutkerashvili, Irakli Chelishvili, Albrecht Harders, George Loladze, Gocha Shatirishvili, Nodar Kipshidze, David Chakhunashvili, Konstantine Chutkerashvili

Get full text

Thyroid-Associated Ophthalmopathy after Radioactive Iodine Therapy for Metastatic Follicular Thyroid Carcinoma by Daisuke Murayama, Soji Toda, Yoichiro Okubo, Hiroyuki Hayashi, Ai Matsui, Mio Yasukawa, Hiroyuki Iwasaki

Get full text

A Rare Case of Large-Vessel Vasculitis following Checkpoint Inhibitor Therapy and Pegfilgrastim by Joseph Mort, Shipra Maheshwari, Nayanika Basu, Patrick Dillon, Kevin Brady, Harry Bear, Trish Millard

“…Checkpoint inhibitors (CPIs) and pegfilgrastim, a long-acting growth factor agent, are vital components of current cancer treatments. Immune-related adverse events (irAEs) such as colitis and pneumonitis are well-established toxicities associated with CPI therapy. …”
Get full text

Potensi Eugenol Fraksi Etil Asetat Bunga Cengkeh terhadap Proliferasi Kanker Serviks (HeLa Cell Line) by Fajri Rahendra Pratama, Annisa Permata Sari, Aprilia Susanti, Hasya Syakira, Amilia Salsabila, Dessy Arisanty

“…<p>Cervix cancer, also known as cervical cancer, is a type of cancer that is caused mainly by oncogenic Human Papillomavirus (HPV), which attacks the cervix. …”
Get full text

Sotorasib resistance triggers epithelial-mesenchymal transition and activates AKT and P38-mediated signaling by Raquel Arantes Megid, Guilherme Gomes Ribeiro, Izabela Natalia Faria Gomes, Ana Carolina Laus, Letícia Ferro Leal, Letícia Ferro Leal, Luciane Sussuchi da Silva, Abu-Bakr Adetayo Ariwoola, Josiane Mourão Dias, Rui Manuel Reis, Rui Manuel Reis, Renato Jose da Silva-Oliveira, Renato Jose da Silva-Oliveira

“…The aim of this study was to generate a sotorasib-resistant cell line via selective pressure and systematically examine the molecular and phenotypic alterations caused by resistance.MethodsMutant NCI-H358 (KRASG12C) were exposed to incremental doses (2–512 nM) of sotorasib. …”
Get full text

Co-infection of SARS‐CoV‐2 and influenza A/B among patients with COVID-19: a systematic review and meta-analysis by Monireh Golpour, Hossein Jalali, Reza Alizadeh-Navaei, Masoumeh Rezaei Talarposhti, Tahoora Mousavi, Ali Asghar Nadi Ghara

Get full text

A Case of Prostatic Carcinoma Manifesting as Cutaneous Facial Nodule by Israel Antonio Esquivel-Pinto, Bertha Torres-Alvarez, Ramiro Jetzabel Gómez-Villa, Juan Pablo Castanedo-Cázares

“…Prostate cancer is the second most frequently diagnosed cancer worldwide and the fifth most common cause of cancer deaths among men. …”
Get full text

Coexistent Non–Small Cell Carcinoma and Small Cell Carcinoma in a Patient Presenting with Hyponatremia by Mitchell D. Ross, Sreeja Biswas Roy, Pradnya D. Patil, Jasmine L. Huang, Nitika Thawani, Ralph Drosten, Tanmay S. Panchabhai

“…Despite recent advances in screening methods, lung cancer remains the leading cause of cancer-related deaths worldwide. …”
Get full text

An Optimized Protocol for Simultaneous Propagation of Patient-derived Organoids and Matching CAFs by Jenny Högström, Taru Muranen

“…Recurrent hormone receptor-positive (HR+) breast cancer is a leading cause of cancer mortality in women. …”
Get full text

Liposomal encapsulation of cholecalciferol mitigates in vivo toxicity and delays tumor growth by Miriam Ezcurra-Hualde, Miriam Ezcurra-Hualde, Sara Zalba, Sara Zalba, Ángela Bella, Ángela Bella, Leire Arrizabalaga, Leire Arrizabalaga, Aline Risson, Aline Risson, Román García-Fuentes, Román García-Fuentes, Celia Gomar, Celia Gomar, Nuria Ardaiz, Nuria Ardaiz, Virginia Belsue, Virginia Belsue, David Ruiz-Guillamon, David Ruiz-Guillamon, Alejandro Serrano-Alcaide, Alejandro Serrano-Alcaide, Ainara Salgado, Ainara Salgado, Fernando Aranda, Fernando Aranda, Maria J. Garrido, Maria J. Garrido, Pedro Berraondo, Pedro Berraondo, Pedro Berraondo

“…VD-LP showed superior antiproliferative effects compared to free vitamin D3 in all tested cancer cell lines. In vivo, VD-LP delayed tumor growth and improved survival without causing hypercalcemia, highlighting its favorable toxicity profile.DiscussionLiposomal encapsulation of vitamin D3 significantly improves its anticancer efficacy while mitigating toxicity, making it a promising strategy for future cancer therapies. …”
Get full text

Prevalensi Kanker Serviks Berdasarkan Paritas di RSUP. Dr. M. Djamil Padang Periode Januari 2011- Desember 2012 by Septia Haryani, Defrin Defrin, Yenita Yenita

“…</p><p><strong>Kata kunci:</strong> kanker serviks, paritas, histopatologi</p><p><strong><em> </em></strong></p><p><strong><em>Abstract</em></strong></p><p><em>The cervical cancer</em><em> is the  first rank cause of cancer death in women of reproductive age in developing countries. …”
Get full text

Impact of the COVID-19 Pandemic on Radiotherapy Supply by Francesco Tramacere, Artor Niccoli Asabella, Maurizio Portaluri, Corinna Altini, Cristina Ferrari, Lilia Bardoscia, Angela Sardaro

Get full text