Prion meeting 2023: implications of a growing field by Tiago F. Outeiro, Tuane C. R. G. Vieira

Get full text

Grade IV oral mucositis treatment with Brazilian green propolis mucoadherent gel by Diogo Alvarenga Silva, Patrícia Carlos Caldeira, Silvia Ferreira de Sousa, Vagner Rodrigues Santos

“…To report a series of clinical cases in the treatment of oral mucositis (OM) in patients with cancer undergoing radiotherapy in the head and neck region. …”
Get full text

Potential of photodynamic therapy using polycationic photosensitizers in the treatment of lung cancer patients with SARS-CoV-2 infection and bacterial complications: Our recent exp... by Gennady Meerovich, Evgeniya Kogan, Igor Romanishkin, Nikolay Zharkov, Sofiya Avraamova, Elena Shchelokova, Ekaterina Akhlyustina, Marina Strakhovskaya, Irina Meerovich, Sofya Demura, Irina Tiganova, Yulia Romanova, Zhi-Long Chen, Igor Reshetov

“…The analysis shows that the photodynamic effect of long-wavelength polycationic photosensitizers suppresses the tumor process (including the destruction of cancer stem cells), SARS-CoV-2 coronavirus infection, Gram-positive and Gram-negative bacteria, including those that can cause pneumonia. …”
Get full text

Hydromethanolic extracts of Morus alba L. (Mulberry) young and ripe fruit induces apoptosis in lung carcinoma cells (A549) by Payal Sargara, M. Nataraj, Ramalingam B. Subramanian, Anjali B. Thakkar

“…(mulberry) young and ripe fruit extracts against lung cancer cells. Cancer ranking as the second leading cause of global mortality, it is essential to investigate natural compounds like phytochemicals for therapeutic benefits. …”
Get full text

Inducers of Autophagy and Cell Death: Focus on Copper Metabolism by Weikang Ling, Shuo Li, Yang Zhu, Xin Wang, Dongmei Jiang, Bo Kang

“…Meanwhile, the application of copper-induced cell death in cancer therapy is discussed, aiming to provide new insights and guiding future research toward advancing cancer therapy.…”
Get full text

Case report: Bevacizumab-induced cerebrovascular events: a case series report and literature review by Ke Chen, Boyang Jiang, Boyang Jiang, Huiping Yan, Huiping Yan, Liu Yang, Liu Yang, Zheling Chen, Zheling Chen

Get full text

Wild pink bayberry free phenolic extract induces mitochondria-dependent apoptosis and G0/G1 cell cycle arrest through p38/MAPK and PI3K/Akt pathway in MDA-MB-231 cancer cells by Wen Xia, Er-sheng Gong, Yanyun Lin, Bisheng Zheng, Wenhan Yang, Tong Li, Sheng Zhang, Peng Li, Rui-hai Liu

“…Polyphenol-rich foods have been shown to be good for cancer prevention as powerful antioxidants. In this study, the mechanisms of wild pink bayberry free phenolic extract (WPBFE) inhibiting the proliferation and inducing apoptotic of MDA-MB-231 breast cancer cells was examined. …”
Get full text

Design of a Medium Scale Ambient PM2.5 Cleaning System by Sheng-Chieh Chen, Qingfeng Cao, Thomas H. Kuehn, Charles Lo, Manoranjan Sahu, Yelia S. Mayya, David Y. H. Pui

Get full text

Diagnostic accuracy of artificial intelligence algorithms to predict remove all macroscopic disease and survival rate after complete surgical cytoreduction in patients with ovarian... by Somayyeh Noei Teymoordash, Hoda Zendehdel, Ali Reza Norouzi, Mahdis Kashian

“…Abstract Background Complete Cytoreduction (CC) in ovarian cancer (OC) has been associated with better outcomes. …”
Get full text

ROR1 CAR-T cells and ferroptosis inducers orchestrate tumor ferroptosis via PC-PUFA2 by Dan Li, Wenjie Zhang, Ruiheng Wang, Shufeng Xie, Yixin Wang, Wanxin Guo, Zixuan Huang, Chaoqun Lu, Liang Shan, Han Liu, Lifang Ma, Xumin Hou, Zhenshu Xu, Jiayi Wang

“…Abstract Background Lung cancer, particularly non-small cell lung cancer (NSCLC), has high recurrence rates and remains a leading cause of cancer-related death, despite recent advances in its treatment. …”
Get full text

Impact of adjuvant trastuzumab therapy and its discontinuation on cardiac function and mortality in patients with early-stage breast cancer: An analysis based on the Japanese Recei... by Keiko Miyazato, Hiroshi Ohtsu, Akihiko Shimomura, Naohiro Yonemoto, Chikako Shimizu, Kazuhiro Sase, Shinichiro Ueda

“…Standard trastuzumab therapy can reduce the risk of early recurrence of HER2-positive breast cancer. However, trastuzumab-induced cardiac dysfunction may force the discontinuation of adjuvant trastuzumab therapy. …”
Get full text

Study on the Function and Mechanism of miR-585-3p Inhibiting the Progression of Ovarian Cancer Cells by Targeting FSCN1 to Block the MAPK Signaling Pathway by Yiming Jia, Jingru Li, Jinfeng Wang, Tianjiao Luo, Xiaoqian Jing, Hongmin Zhao

“…Ovarian cancer (OC) is the leading cause of death for women diagnosed with gynecological cancer. …”
Get full text

Brief intervention to enhance cessation of smokeless tobacco use in newly diagnosed patients with head and neck cancers: A randomized controlled trial in patient-relative dyads by Sai Krishna Tikka, Avinash Shukla, Ripu D. Arora, Sharda Singh, Supriya Mahant, Sachin Verma, Lokesh K. Singh

“…Introduction: Tobacco use is a major causative factor for head and neck cancers (HNC). Continued use of tobacco even after cancer diagnosis is common and is associated with all-cause and cancer-specific mortality, cancer recurrence and poor treatment response. …”
Get full text

Mechanisms Mediating the Effects of γ-Tocotrienol When Used in Combination with PPARγ Agonists or Antagonists on MCF-7 and MDA-MB-231 Breast Cancer Cells by Abhita Malaviya, Paul W. Sylvester

“…Combined treatment of γ-tocotrienol and PPARγ agonists caused an increase in transcription activity of PPARγ along with increased expression of PPARγ and RXR, and decrease in PPARγ coactivators, CBP p/300, CBP C-20, and SRC-1, in both breast cancer cell lines. …”
Get full text

RETRACTED: LncRNA CCAT2 promotes the proliferation and metastasis of colorectal cancer through activation of the ERK and Wnt signaling pathways by regulating GNB2 expression by Jinhai Tian, Xu Cao, Zongying Jiang, Jia Wang, Wan Fan, Shaoting Zhang, Sien Zhao, Jianmin Sun

“…Abstract Background Colorectal cancer (CRC) is a prevalent and lethal tumor, with metastasis being the leading cause of mortality. …”
Get full text

A comparative analysis and survival analysis of open versus minimally invasive radical antegrade modular pancreatosplenectomy for pancreatic cancer: a systematic review and meta-an... by Yating Zhou, Fei Xue

“…BackgroundPancreatic ductal adenocarcinoma (PDAC) is a major public health concern, ranking as the fourth leading cause of cancer-related mortality in the United States. …”
Get full text

Treatment of a mutant KRAS lung cancer cell line with polyisoprenylated cysteinyl amide inhibitors activates the MAPK pathway, inhibits cell migration and induces apoptosis. by Matthew D Gregory, Kweku Ofosu-Asante, Jassy Mary S Lazarte, Pablo E Puente, Nada Tawfeeq, Nadine Belony, Yong Huang, Ite A Offringa, Nazarius S Lamango

“…Polyisoprenylated Cysteinyl amide Inhibitors (PCAIs) constitute a group of potential cancer therapy agents that we designed to specifically disrupt and suppress hyperactive G-protein signaling, such as that caused by mutated RAS proteins. …”
Get full text

CD36 inhibition enhances the anti-proliferative effects of PI3K inhibitors in PTEN-loss anti-HER2 resistant breast cancer cells by You-Yu Liu, Wei-Lun Huang, Sin-Tian Wang, Hui-Ping Hsu, Tzu-Ching Kao, Wei-Pang Chung, Kung-Chia Young

“…However, subsequent reprogramed tumor progression due to PI3K signaling pathway activation by PIK3CA mutations and/or PTEN-loss cause anti-HER2 resistance. Previously, alpha isoform-specific PI3K inhibitors were shown to potentiate HER2-targeted therapy in breast cancer cells carrying PI3K pathway alterations with less potent effects on PTEN-loss than PIK3CA-mutant cells. …”
Get full text

Novel combination strategy of high intensity focused ultrasound (HIFU) and checkpoint blockade boosted by bioinspired and oxygen-supplied nanoprobe for multimodal imaging-guided ca... by Ying Zhou, Chen Cheng, Qi Wang, Min Zheng, Pan Li, Yang Zhou, Yuting Cao, Li Wan, Xun Guo, Xiaohong Lin, Rui Tang, Hongye He, Nianhong Wu, Qiaoqi Chen, Yaqin Hu, Xialin Xiong, Faqi Li

Get full text

Trends and ethnic disparity in endometrial cancer mortality in South Africa (1999-2018): A population-based Age-period-cohort and Join point regression analyses. by Gbenga Olorunfemi, Elena Libhaber, Oliver Chukwujekwu Ezechi, Eustasius Musenge

“…<h4>Background</h4>Endometrial cancer is the sixth leading cause of cancer among females and about 97,000 global deaths of endometrial cancer. …”
Get full text