Study protocol: multi-centre, randomised controlled clinical trial exploring stromal targeting in locally advanced pancreatic cancer; STARPAC2 by Hemant M. Kocher, BCI-STARPAC2 team, BPTB team, Precision-Panc team, Peter Sasieni, Pippa Corrie, Mairéad G. McNamara, Debashis Sarker, Fieke E. M. Froeling, Alan Christie, Roopinder Gillmore, Khurum Khan, David Propper

“…Abstract Background Pancreatic cancer (PDAC: pancreatic ductal adenocarcinoma, the commonest form), a lethal disease, is best treated with surgical excision but is feasible in less than a fifth of patients. …”
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Impact of surgical site infection (SSI) following gynaecological cancer surgery in the UK: a trainee-led multicentre audit and service evaluation by Rachel L O’Donnell, Georgios Angelopoulos, James P Beirne, Ioannis Biliatis, Helen Bolton, Melissa Bradbury, Elaine Craig, Ketan Gajjar, Michelle L Mackintosh, Wendy MacNab, Thumuluru Kavitha Madhuri, Mark McComiskey, Eva Myriokefalitaki, Claire L Newton, Nithya Ratnavelu, Sian E Taylor, Amudha Thangavelu, Sarah A Rhodes, Emma J Crosbie, Richard J Edmondson, Yee-Loi Louise Wan

“…Little is known about the incidence of SSI and its consequences in women undergoing surgery for gynaecological cancer. Our aim was to perform the first national audit of SSI following gynaecological cancer surgery through the establishment of a UK-wide trainee-led research network.Design and setting In a prospective audit, we collected data from all women undergoing laparotomy for suspected gynaecological cancer at 12 specialist oncology centres in the UK during an 8-week period in 2015. …”
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To Explore the Effects of Acupuncture and Medical Treatment at Different Times on the Gastrointestinal Reaction and White Blood Cell Count of Patients with Lung Cancer Chemotherapy by Qingchun Zhao, Hui Du, Jinghao Liu, Yu Hua, Xiaoyu Niu, Jun Chen

“…Tropisetron hydrochloride is an effective treatment for patients with lung cancer before chemotherapy, which can effectively improve the side effects of nausea and vomiting caused by chemotherapy, reduce the white blood cell count, and improve the quality of life of patients; it plays an important role in the improvement of prognosis.…”
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Venous thromboembolism incidence and risk factors associated with immune checkpoint inhibitors among patients with advanced non-small cell lung cancer by Chi Nguyen, Alok A Khorana, John Barron, Jennell Palaia, Lisa Rosenblatt, Radhika Pisupati, Ning Huang, Kerrin Gallagher, T Christopher Bond

“…Background Venous thromboembolism (VTE) is a significant cause of morbidity and mortality in patients with lung cancer. …”
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Mechanistic Insights into the Inhibition of Colorectal Cancer by BuShenFang through Adenomatous Polyposis Coli Expression and Wnt/β-catenin Pathway Regulation by Khang Wen Goh, Jie Ji, Hiu Ching Phang, Xian Gu, Rajesh Sreedharan Nair, Xiaohui Wei, Mohammed Tahir Ansari, Kai Bin Liew

“… Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide. …”
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Effect of Ward Noise Reduction Technology Combined with Music Therapy on Negative Emotions in Inpatients Undergoing Gastric Cancer Radiotherapy: A Retrospective Study by Fengyun Zhao, Zhen Sun, Wenbo Niu

“…Background: Gastric cancer is a common malignant tumour in clinics. Noise affects the condition of patients with gastric cancer to a certain extent. …”
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Long-read 16S rRNA amplicon sequencing reveals microbial characteristics in patients with colorectal adenomas and carcinoma lesions in Egypt by Asmaa A. El Leithy, Amira Salah El-Din Youssef, Auhood Nassar, Ramy K. Aziz, Nadin M. Khaled, Mina T. Mahrous, Ghobrial N. Farahat, Aya H. Mohamed, Yasser Mabrouk Bakr

“…Abstract Background Colorectal cancer (CRC) is among the five leading causes of cancer incidence and mortality. …”
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Non-Invasive Detection of Tumors by Volatile Organic Compounds in Urine by Tomoaki Hara, Sikun Meng, Yasuko Arao, Yoshiko Saito, Kana Inoue, Aya Hasan Alshammari, Hideyuki Hatakeyama, Eric di Luccio, Andrea Vecchione, Takaaki Hirotsu, Hideshi Ishii

“…Cancer is one of the major causes of death, and as it becomes more malignant, it becomes an intractable disease that is difficult to cure completely. …”
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Healthcare Resource Utilization and Costs Among Commercially Insured Patients With Advanced or Recurrent Endometrial Cancer Initiating First-Line Therapy in the United States by Monica Kobayashi, Jamie Garside, Joehl Nguyen

“…**Background:** Endometrial cancer (EC) represents a substantial economic burden for patients in the United States. …”
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Bilateral Vocal Cord Paralysis and Cervicolumbar Radiculopathy as the Presenting Paraneoplastic Manifestations of Small Cell Lung Cancer: A Case Report and Literature Review by Jeffrey C. Yeung, C. Elizabeth Pringle, Harmanjatinder S. Sekhon, Shaun J. Kilty, Kristian Macdonald

“…This led to an endobronchial biopsy of a paratracheal lymph node, which confirmed the diagnosis of small cell lung cancer. Conclusion. Paraneoplastic neuropathy is a rare cause of BVCP and should be considered when more common pathologies are ruled out. …”
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Apoptosis of colon cancer CT-26 cells induced polysaccharide from Cyclocarya paliurus and its phosphorylated derivative via intrinsic mitochondrial passway by Liuming Xie, Mingyue Shen, Rong Huang, Xuan Liu, Yue Yu, Hanyu Lu, Jianhua Xie

“…These results suggest CP is a potential natural therapeutic agent for colon cancer and phosphorylation represents an effective method of enhancing the antitumor activity of CP.…”
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An improved soft voting-based machine learning technique to detect breast cancer utilizing effective feature selection and SMOTE-ENN class balancing by Indu Chhillar, Ajmer Singh

“…Abstract Breast cancer is the primary cause of death among women globally, and it is becoming more prevalent. …”
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Androgen Metabolism Gene Polymorphisms, Associations with Prostate Cancer Risk and Pathological Characteristics: A Comparative Analysis between South African and Senegalese Men by Pedro Fernandez, Charnita M. Zeigler-Johnson, Elaine Spangler, André van der Merwe, Mohamed Jalloh, Serigne M. Gueye, Timothy R. Rebbeck

“…Prostate cancer is the most common cancer in men in developed countries and the leading cause of mortality in males in less developed countries. …”
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Exosomes Derived from SW480-Resistant Colon Cancer Cells Are Promote Angiogenesis via BMP-2/Smad5 Signaling Pathway by Song Yang, Lei Yao, Xiaolong Wang, Hao Sun, Chaogang Du, Chengpeng Song, Jingyu Fu, Yongjun Wu, Hongwu Huang, Chuansi Wang, Yongsen Wang, Yixiang Xie

“…We aim to investigate the relationship between drug resistance and angiogenesis in SW480 colon cancer cells and the possible underlying mechanism. …”
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Evaluation of the Cytotoxicity of Aqueous Extract and Oleo-Essential Oil of Dorema ammoniacum Plant Oleo-Gum Resin in Some Human Cancer Cell Lines by Pardis Mohammadi Pour, Spideh Bidad, Gholamreza Bahrami, Leila Hosseinzadeh, Mahdi Mojarrab, Mohammad Hosein Farzaei

“…Aqueous extract and essential oil reduced the viability of A549 cancer cells in a concentration-dependent manner. …”
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Circulating Free RNA as a Therapeutic Evaluation in Diffuse Large B-cell Lymphoma: A Case Series from the Indonesian Cancer Center by Noorwati Sutandyo, Ikhwan Rinaldi, Lyana Setiawan, Christine Sugiarto, Yuniar Harris Prayitno

“…Cancer is still the leading cause of death worldwide. …”
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Anticancer Potential of Fruit Extracts from Vatica diospyroides Symington Type SS and Their Effect on Program Cell Death of Cervical Cancer Cell Lines by Atchara Chothiphirat, Kesara Nittayaboon, Kanyanatt Kanokwiroon, Theera Srisawat, Raphatphorn Navakanitworakul

“…Hence, the ACE could be further exploited as a potential lead in cancer treatment.…”
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Highly efficient assessment and selective determination of pancreatic cancer biomarker CA-19-9 using co-electrodeposited MXene-AgNPs nanocomposite by Mahsa Mirzayi, Balal Khalilzadeh, Sattar Akbari Nakhjavani, Rahim Mohammad-Rezaei

“…An ultrasensitive and label-free electrochemical immunosensor based on MXene-AgNPs nanocomposite is reported for pancreas cancer diagnostics. Ease of deposition, high speed, thickness of deposition and high efficiency of these biosensors are their special and fundamental advantages.For this purpose, a pencil graphite electrode (PGE) was modified by silver and MXene (Ti3C2Tx (to increase efficiency and also the active surface area of PGE. …”
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YTHDF1 Regulates RELA m6A Modification and Activates the NF‐Kappa B Signaling Pathway to Promote the Mechanism of Gastric Cancer by Yangyuan Huang, Shihao Liang, Liping Li, Qingyu Zeng, Bin Li

“…ABSTRACT Background Gastric cancer (GC) is an important cause of death. Molecular targeted therapy and immunotherapy are progressing rapidly. …”
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Perioperative or neo/adjuvant chemoimmunotherapy versus chemotherapy for resectable non-small cell lung cancer: a systematic review and network meta-analysis by Qiong Zhang, Jia Duan, Yuanmei Zhang, Lei Yang, Duo Li

“…Abstract Introduction Lung cancer, particularly non-small cell lung cancer (NSCLC), is a leading cause of cancer-related deaths globally. …”
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