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541
A Urine Metabonomics Study of Rat Bladder Cancer by Combining Gas Chromatography-Mass Spectrometry with Random Forest Algorithm
Published 2020-01-01“…A urine metabolomics study based on gas chromatography-mass spectrometry (GC-MS) and multivariate statistical analysis was applied to distinguish rat bladder cancer. Urine samples with different stages were collected from animal models, i.e., the early stage, medium stage, and advanced stage of the bladder cancer model group and healthy group. …”
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542
Anti-proliferative and photodynamic activities of Senna didymobotrya (Fresen.) leaf alkaloid-rich extracts against breast cancer cells
Published 2025-01-01“…Abstract Background Amongst all neoplastic diseases, breast cancer represents a major cause of death among the female population in developed and developing countries. …”
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543
CRAT downregulation promotes ovarian cancer progression by facilitating mitochondrial metabolism through decreasing the acetylation of PGC-1α
Published 2025-01-01“…Our bioinformatics analysis using public database revealed a significant decrease of CRAT expression in ovarian cancer (OC). However, the functions of CRAT have rarely been investigated in human cancers, especially in OC. …”
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544
The Proapoptotic Effect of MB-653 Is Associated with the Modulation of Metastasis and Invasiveness-Related Signalling Pathways in Human Colorectal Cancer Cells
Published 2025-01-01“…Colorectal cancer is one of the most common cancers worldwide and has a high mortality rate. …”
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545
Expression of Intratumoral IGF-II Is Regulated by the Gene Imprinting Status in Triple Negative Breast Cancer from Vietnamese Patients
Published 2015-01-01“…African American women suffer higher incidence and mortality of triple negative breast cancer (TNBC) than Caucasian women. TNBC is very aggressive, causing the worst clinical outcome. …”
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546
Bufalin targets the SRC-3/c-Myc pathway in chemoresistant cells to regulate metastasis induced by chemoresistance in colorectal cancer
Published 2025-02-01“…Moreover, the clinical drug cinobufacini and its main active monomer bufalin reduced liver metastasis of colorectal cancer caused by chemoresistance in vivo. Conclusion Bufalin can target the SRC-3/c-Myc signaling pathway to affect the prometastatic effect of chemoresistant cells, suggesting that bufalin may be used as a new adjuvant antimetastatic therapy for colorectal cancer.…”
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547
Activating Transcription Factor 5 Promotes Tumorigenic Capability in Cervical Cancer Through the Wnt/β-Catenin Signaling Pathway
Published 2025-01-01“…Fengjuan Shi,1,2 Yumei Wei,2 Yingmei Huang,2 Desheng Yao1 1Department of Gynecologic Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, People’s Republic of China; 2Department of Gynecology, the Fifth Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People’s Republic of ChinaCorrespondence: Desheng Yao, Email yaodesheng@gxmu.edu.cnPurpose: Cervical cancer is the fourth leading cause of cancer-related death in women. …”
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548
Assessing the rates of false-positive ovarian cancer screenings and surgical interventions associated with screening tools: a systematic review
Published 2024-07-01“…No studies examined the effect these interventions had on patients’ quality of life or directly reported the associated costs of these interventions.Conclusion This review highlights the significant variability in ovarian cancer screening results, which lead to unnecessary and invasive surgical procedures causing complications such as perforation, blood loss and bowel injury.…”
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549
Could serum Raftlin and GPER-1levels be new biomarkers for early detection of non-small cell lung cancer?
Published 2025-01-01“…Abstract Background Lung cancer is the leading cause of cancer-related deaths worldwide. …”
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550
Association of polymorphism <i>TP53</i> Arg72Pro with radon-induced lung cancer in the Kazakh population
Published 2019-08-01“…Radon exposure is classified as the second most important cause of lung cancer. According to the experts, the contribution of natural sources to the average annual radiation dose of the Kazakh population currently stands at 80 %, including 50 % from radon. …”
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551
Dietary Exposure to Aflatoxins in Some Randomly Selected Foods and Cancer Risk Estimations of Cereals Consumed on a Ghanaian Market
Published 2022-01-01“…Aflatoxins have gained so much reputation among all mycotoxins due to their notoriety in causing countless adverse health effects on humans as well as animals. …”
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552
A prospective model of the potential clinical and economic impact of cervical cancer screening supported by a mobile phone app.
Published 2025-01-01“…<h4>Introduction</h4>Cervical cancer is a preventable and highly curable disease when detected early and adequately treated, yet it remains the leading cause of cancer-related death in women in Kenya due to low screening coverage and treatment. …”
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553
Exploring the anti-metastatic potential of sunitinib and novel analogs in colorectal cancer: insights into HIF-1α mediated metastasis
Published 2025-02-01“…Metastasis, the primary cause of cancer-related deaths, is attributed to various factors including tumor hypoxia. …”
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554
Carnitine palmitoyltransferase 1C promotes EMT-associated cisplatin resistance in non-small cell lung cancer cells
Published 2025-01-01“…Objective: Lung cancer is the most common cause of cancer-related deaths worldwide. …”
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555
Neuropsychological features of patients of reproductive age diagnosed with breast cancer at the stage of surgical treatment using xenon-oxygen therapy
Published 2021-09-01“…To study functional changes in the neuropsychological status of reproductive age patients with newly diagnosed breast cancer and to assess the possibility of using xenon-oxygen therapy to correct disorders.Patients and methods. …”
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556
Utilizing TP53 hotspot mutations as effective predictors of gemcitabine treatment outcome in non-small-cell lung cancer
Published 2025-01-01“…Gemcitabine is a treatment option for patients with non-small cell lung cancer (NSCLC) who carry TP53 hotspot mutations. This potential effectiveness might arise from its ability to disrupt DNA damage repair processes, leading to G2/M phase cell cycle arrest or an augmentation of mitotic abnormalities, eventually cause cell death. …”
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557
Circular RNA circBNC2 inhibits tumorigenesis by modulating ferroptosis and acts as a nanotherapeutic target in prostate cancer
Published 2025-01-01“…Abstract Background Metastasis is a leading cause of cancer-related death in castration-resistant prostate cancer (CRPC) patients. …”
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558
TP53 germline testing and hereditary cancer: how somatic events and clinical criteria affect variant detection rate
Published 2025-01-01“…The implementation of multi-gene panel germline testing in different clinical settings has led to the identification of TP53 PV carriers outside the classic LFS-associated cancer phenotypes, leading to a broader cancer phenotypic redefinition and to the renaming of the condition as “heritable TP53-related cancer syndrome” (hTP53rc). …”
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559
The Second Incisional Site Metastasis in a Patient with Cervical Carcinoma: A Case Report
Published 2013-12-01“… Cervical cancer is the third most commonly diagnosed cancer and the fourth leading cause of cancer deaths in females worldwide. …”
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560
Asuhan Keperawatan pada Anak dengan Gangguan Nutrisi Akibat Kanker melalui Pendekatan Model Adaptasi Roy
Published 2012-06-01“…Roy Adaptation Model is based on the consideration that children with cancer require special handling and complicated chemotherapy that affects the digestive system disorders that cause malnutrition. …”
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