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441
Role of Epstein-Barr Virus and Human Papilloma Virus in the Development of Oropharyngeal Cancer: A Literature Review
Published 2022-01-01“…The aim of this review was to describe the association and related mechanisms between HPV, EBV, and the development of oral and oropharyngeal cancer. A search for scientific evidence was carried out in electronic databases (MEDLINE/PubMed, SciELO). …”
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442
How Do Trematodes Induce Cancer? A Possible Evolutionary Adaptation of an Oncogenic Agent Transmitted by Flukes
Published 2025-01-01“…The exact nature of the mechanism by which cancer is induced by these parasites is unknown. Here, we provide a new hypothesis suggesting that flukes are not the primary cause of cancer but act as vectors of cancer‐inducing microbial pathogens. …”
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443
Small Cell Lung Cancer Patient with Profound Hyponatremia and Acute Neurological Symptoms: An Effective Treatment with Fludrocortisone
Published 2015-01-01“…Hyponatremia is a frequent electrolyte abnormality in patients with small cell lung cancer (SCLC). Being usually asymptomatic, hyponatremia may cause symptoms like nausea, fatigue, disorientation, headache, muscle cramps, or even seizures, particularly if severe and rapid decrease of serum sodium levels occurs. …”
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444
Acute Interstitial Nephritis in a Patient with Non-Small Cell Lung Cancer under Immunotherapy with Nivolumab
Published 2019-01-01“…We present the case of a 60-year-old man with a history of non-small cell lung cancer, who developed acute kidney injury (AKI) approximately 3.5 months after initiation of immunotherapy with nivolumab. …”
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445
The impact of an imperfect vaccine and pap cytologyscreening on the transmission of human papillomavirus and occurrenceof associated cervical dysplasia and cancer
Published 2013-05-01“…It is shown that the backward bifurcation is caused bythe imperfect nature of the HPV vaccine or the HPV-induced andcancer-induced mortality in females. …”
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446
CircRNAs as Possible Potential Biomarkers for Breast Cancer Prognosis and Chemotherapy Response: A Comprehensive Study
Published 2024-10-01“… Background: Breast cancer is the leading cause of death for women worldwide. …”
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447
Early, integrated palliative care for people with chronic respiratory disease: lessons learnt from lung cancer
Published 2025-02-01“…Lung cancer and chronic non-malignant respiratory disease cause pervasive, multifactorial suffering for patients and informal carers alike. …”
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448
Fenofibrate Exerts Antitumor Effects in Colon Cancer via Regulation of DNMT1 and CDKN2A
Published 2021-01-01“…Recently, the potential role of PPARA in other pathological conditions, such as cancers, has been recognized. Here, using bioinformatics analysis, we found that PPARA was expressed at relatively low levels in pancancers, and Kaplan-Meier analyses revealed that high PPARA protein expression was correlated with better survival of patients with colon cancer. …”
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449
In Situ Transformable Nanoparticle Effectively Suppresses Bladder Cancer by Damaging Mitochondria and Blocking Mitochondrial Autophagy Flux
Published 2025-02-01“…However, the low drug delivery efficiency caused by lysosomal sequestration and the activation of protective mitochondrial autophagy severely restricts the therapeutic efficacy. …”
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450
Effects of silkworm pupa protein on apoptosis and energy metabolism in human colon cancer DLD-1 cells
Published 2022-09-01“…Additionally, SPP could significantly inhibited mitochondrial metabolism and glycolysis of DLD-1 cells and decreased cell energy metabolism in all groups treated with different doses. Conclusion: SPP can cause oxidative damage, promote apoptosis, and reduce mitochondrial respiratory and glycolysis rate in colon cancer DLD-1 cells, which reveals that SPP has the potential to serve as the anti-cancer drugs in the future, but further experimental evidence is needed.…”
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451
Volatile Organic Compounds for the Prediction of Lung Cancer by Using Ensembled Machine Learning Model and Feature Selection
Published 2025-01-01“…The advancement of biomarkers is critically important at present, as lung cancer is a leading cause of death. In the present study, volatile organic compounds (VOCs) are considered as biomarkers to predict lung cancer. …”
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452
Ensemble Classification Model With CFS-IGWO–Based Feature Selection for Cancer Detection Using Microarray Data
Published 2024-01-01“…Cancer is the top cause of death worldwide, and machine learning (ML) has made an indelible mark on the field of early cancer detection, thereby lowering the death toll. …”
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453
HOXB8 mediates resistance to cetuximab in colorectal cancer cells through activation of the STAT3 pathway
Published 2024-10-01“…Among the prevalent monoclonal antibodies for treating RAS/BRAF wild-type metastatic colorectal cancer (mCRC) patients, cetuximab stands out, but resistance to cetuximab frequently arises in targeted treatments. …”
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454
Iron deficiency and symptoms in women aged 20–49 years and relation to upper gastrointestinal and colon cancers
Published 2022-07-01“…Objective Iron deficiency anaemia (IDA) in women aged 20–49 years may be caused by menses or gastrointestinal cancer. Data are sparse on the yield of endoscopy/colonoscopy in this population. …”
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455
The SIX1/LDHA Axis Promotes Lactate Accumulation and Leads to NK Cell Dysfunction in Pancreatic Cancer
Published 2023-01-01“…Background. Pancreatic cancer (PC) is a malignant cancer with poor prognosis and high mortality rate. …”
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456
Therapeutic Implications of a Polymethoxylated Flavone, Tangeretin, in the Management of Cancer via Modulation of Different Molecular Pathways
Published 2021-01-01“…In addition, tangeretin is known to exhibit considerable selective toxicity to many types of cancer cell proliferation such as ovarian, brain, blood, and skin cancer. …”
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457
Fine-Grained Lung Cancer Classification from PET and CT Images Based on Multidimensional Attention Mechanism
Published 2020-01-01“…Due to restrictions caused by single modality images of dataset as well as the lack of approaches that allow for a reliable extraction of fine-grained features from different imaging modalities, research regarding the automated diagnosis of lung cancer based on noninvasive clinical images requires further study. …”
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458
The AhR pathway regulation in phthalates-induced cancer promotion, progression and metastasis: a scoping review
Published 2025-01-01“…Abstract Background Cancer remains a leading cause of death worldwide. …”
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459
CLDN4 as a Novel Diagnostic and Prognostic Biomarker and Its Association with Immune Infiltrates in Ovarian Cancer
Published 2023-01-01“…Ovarian cancer (OC) is the seventh most prevalent type of cancer in women and the second most common cause of cancer-related deaths in women worldwide. …”
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460
Identification of HPV16 E1 and E2-specific T cells in the oropharyngeal cancer tumor microenvironment
Published 2023-03-01“…The viral etiology of these cancers provides the opportunity for antigen-directed therapies that are restricted in scope compared with cancers without viral components. …”
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