Canadian Cardiovascular Society and Canadian Thoracic Society Position Statement on Pulmonary Arterial Hypertension by David Langleben, Stephen Archer, John Granton, Andrew M Hirsch, Robert D Levy, Sanjay Mehta, Evangelos Michelakis, Duncan J Stewart

“…The present document is intended to act as an update for the clinician, to provide a template for the initial evaluation of patients, to enable the understanding of current therapeutic paradigms based on approved indications for Canada, to highlight new therapies on the horizon, and to state the positions of the Canadian Cardiovascular Society and the Canadian Thoracic Society on resource management for pulmonary arterial hypertension in Canada.…”
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Safety and Efficacy of Hemospray® in Upper Gastrointestinal Bleeding by Alan Hoi Lun Yau, George Ou, Cherry Galorport, Jack Amar, Brian Bressler, Fergal Donnellan, Hin Hin Ko, Eric Lam, Robert Allan Enns

“…BACKGROUND: Hemospray (Cook Medical, USA) has recently been approved in Canada for the management of nonvariceal upper gastrointestional bleeding (UGIB).…”
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Responses of spectral indices to heat and drought differ by tree size in Douglas-fir by Olivia J.M. Waite, Nicholas C. Coops, Samuel Grubinger, Miriam Isaac-Renton, Jonathan Degner, Jacob King, Alex Liu

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Humoral and cell-mediated immune responses to COVID-19 vaccines up to 6 months post three-dose primary series in adults with inborn errors of immunity and their breakthrough infect... by Dana Unninayar, Emilia L. Falcone, Hugo Chapdelaine, Donald C. Vinh, Karina A. Top, Beata Derfalvi, Thomas B. Issekutz, Hélène Decaluwe, Anne Pham-Huy, Julia Upton, Stephen D. Betschel, Tamar Rubin, Sneha Suresh, Nicola A. M. Wright, Luis Murguía-Favela, Tatiana Kalashnikova, Lisa Barrett, Sharon Oldford, Marc-Andre Langlois, Corey Arnold, Manish Sadarangani, Tinghua Zhang, Tim Ramsay, Dina Yazji, Juthaporn Cowan, Juthaporn Cowan

“…Therefore, the purpose of this study was to examine HI and CMI responses up to 6 months post-COVID-19 vaccine dose 3 in adults with IEIs.MethodsA multi-center prospective observational study was conducted across Canada to collect severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-specific HI and CMI data at 4- and 24-week intervals after vaccine doses 2 and 3 (D2 + 4wk/D2 + 24wk/D3 + 4wk/D3 + 24wk).ResultsA total of 149 adults with IEIs and 423 healthy controls were recruited from July 2021 to October 2023. …”
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Clinical Recommendations for the Use of Recombinant Human Erythropoietin in Patients with Hepatitis C Virus Being Treated with Ribavirin by Morris Sherman, Lawrence Cohen, Mary Anne Cooper, Magdy Elkashab, Victor Feinman, David Fletcher, Nigel Girgrah, Jenny Heathcote, Mark Levstik, William B McNaull, David Wong, Florence Wong, Colina Yim

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Electroencephalography Biomarkers of α5-GABA Positive Allosteric Modulators in Rodents by Frank Mazza, Alexandre Guet-McCreight, Thomas D. Prevot, Taufik Valiante, Etienne Sibille, Etay Hay

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A roadmap to implementing machine learning in healthcare: from concept to practice by Adam Paul Yan, Adam Paul Yan, Lin Lawrence Guo, Jiro Inoue, Santiago Eduardo Arciniegas, Emily Vettese, Agata Wolochacz, Nicole Crellin-Parsons, Brandon Purves, Steven Wallace, Azaz Patel, Medhat Roshdi, Karim Jessa, Karim Jessa, Bren Cardiff, Lillian Sung, Lillian Sung, Lillian Sung

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Practice patterns among early-career primary care (ECPC) physicians and workforce planning implications: protocol for a mixed methods study by Richard J Gibson, Tara Sampalli, Tara Kiran, Richard H Glazier, Agnes Grudniewicz, Kimberlyn McGrail, David Snadden, Ian Scott, M Ruth Lavergne, Laurie J Goldsmith, David Rudoler, Emily Gard Marshall, Megan Ahuja, Doug Blackie, Fred Burge, Steve Hawrylyshyn, Lindsay Hedden, Jacalynne Hernandez-Lee, Kathleen Horrey, Mike Joyce, Adrian MacKenzie, Maria Mathews, Rita McCracken, Madeleine McKay, Charmaine McPherson, Goldis Mitra, Gail Tomblin Murphy, Sabrina T Wong

“…We will conduct semi-structured in-depth interviews with family medicine residents and early-career PCPs and analyse survey data collected by the College of Family Physicians of Canada. We will also analyse linked administrative health data within each province. …”
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Risk Factors for Hospital Readmission Following Noncardiac Surgery: International Cohort Study by Michael H. McGillion, RN, PhD, Flavia K. Borges, MD, PhD, David Conen, MD, MPH, Daniel I. Sessler, MD, Brenda L. Coleman, RN, PhD, Maura Marcucci, MD, MSc, Carley Ouellette, RN, MSc, Marissa Bird, RN, PhD, Carly Whitmore, RN, PhD, Shaunattonie Henry, RN, PhD, Sandra Ofori, MD, MSc, Shirley M. Pettit, RN, Deborah M. Bedini, RN, MHS, Leslie P. Gauthier, MScT, Jennifer Lounsbury, RN(EC), MN, Nancy M. Carter, RN, PhD, Vikas Tandon, MD, Ameen Patel, MD, Teresa Cafaro, MD, MSc, Marko R. Simunovic, MD, John A. Harlock, MD, Diane Heels-Ansdell, MSc, Fadi Elias, MD, MS, Theodore Rapanos, MD, Shawn Forbes, MD, Elizabeth Peter, RN, PhD, Judy Watt-Watson, RN, PhD, Kelly Metcalfe, RN, PhD, Sandra L. Carroll, RN, PhD, Philip J. Devereaux, MD, PhD

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Seroprevalences of Hepatitis B Virus and Hepatitis C Virus among Participants of an Asian Health Fair in the Lower Mainland, British Columbia by Stephen Ip, Jo-Ann Ford, Kirby Lau, Vladimir Marquez, Marisa Guan, Carolyn Klassen, Jessica Chan, WC Peter Kwan, Mel Krajden, Eric M Yoshida

“…BACKGROUND: The seroprevalences of hepatitis B virus (HBV) and hepatitis C virus (HCV) are 0.4% and 0.8%, respectively, in Canada, but varying rates have been reported in different populations.…”
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Predictors of Relapse to Significant Alcohol Drinking after Liver Transplantation by Zamil Karim, Pongphob Intaraprasong, Charles H Scudamore, Siegfried R Erb, John G Soos, Elsie Cheung, Polly Cooper, Andrzej K Buzckowski, Stephen W Chung, Urs P Steinbrecher, Eric M Yoshida

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Carriage of Neisseria Species in Communities with Different Rates of Meningococcal Disease by Nicole Le Saux, Fraser Ashton, Maksudar Rahman, Alan Ryan, Edward Ellis, Susan Tamblyn, Joan Morris, Al Borczyk, Caroll Mallory, Donald Mikel, Stephen Thompson, Lyall Black, Barbara Lacey, Chandar Anand

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Noninvasive Ventilation Practice Patterns for Acute Respiratory Failure in Canadian Tertiary Care Centres: A Descriptive Analysis by Geneviève C Digby, Sean P Keenan, Christopher M Parker, Tasnim Sinuff, Karen E Burns, Sangeeta Mehta, Juan J Ronco, Demetrios J Kutsogiannis, Louise Rose, Najib T Ayas, Luc R Berthiaume, Christine L D’Arsigny, Daniel E Stollery, John Muscedere

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Diagnostic Evaluation and Management of Chronic Thromboembolic Pulmonary Hypertension: A Clinical Practice Guideline by Sanjay Mehta, Doug Helmersen, Steeve Provencher, Naushad Hirani, Fraser D Rubens, Marc De Perrot, Mark Blostein, Kim Boutet, George Chandy, Carole Dennie, John Granton, Paul Hernandez, Andrew M Hirsch, Karen Laframboise, Robert D Levy, Dale Lien, Simon Martel, Gerard Shoemaker, John Swiston, Justin Weinkauf

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Liver Transplantation for Hepatic Epithelioid Hemangioendothelioma: The Canadian Multicentre Experience by Carmine G Nudo, Eric M Yoshida, Vincent G Bain, Denis Marleau, Phil Wong, Paul J Marotta, Eberhard Renner, Kymberly D Watt, Marc Deschênes

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Antimicrobial Regimens Prescribed by Canadian Physicians for Chemotherapy-Induced Febrile Neutropenic Episodes by Michel Laverdière, Eric J Bow, Coleman Rotstein, Stratis Ioannou, Danielle Carr, Narguess Moghaddam, the Canadian Fluconazole Study Group

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Hepatitis B and Hepatitis C Viral Infections in Patients with Chronic Lymphocytic Leukemia by Gerald Y Minuk, Betty Lerner, Spencer B Gibson, James B Johnston, Julia Uhanova, Anton Andonov, Jun Wu

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Benchmarking Pain Outcomes for Children with Sickle Cell Disease Hospitalized in a Tertiary Referral Pediatric Hospital by Abi Vijenthira, Jennifer Stinson, Jeremy Friedman, Lori Palozzi, Anna Taddio, Dennis Scolnik, Charles Victor, Melanie Kirby-Allen, Fiona Campbell

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Facilitators and Solutions for Practicing Optimal Guided Asthma Self-Management: The Physician Perspective by Alexandrine J Lamontagne, Sandra Peláez, Roland Grad, Lucie Blais, Kim L Lavoie, Simon L Bacon, Hélène Guay, Annie Gauthier, Martha L McKinney, Pierre Ernst, Johanne Collin, Francine M Ducharme

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Training Highly Qualified Health Research Personnel: The Pain in Child Health Consortium by Carl L von Baeyer, Bonnie J Stevens, Christine T Chambers, Kenneth D Craig, G Allen Finley, Ruth E Grunau, C Celeste Johnston, Rebecca Pillai Riddell, Jennifer N Stinson, Justine Dol, Marsha Campbell-Yeo, Patrick J McGrath

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