Showing 21 - 40 results of 304 for search '"CRISPR"', query time: 0.06s Refine Results
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    A bacteriophage model based on CRISPR/Cas immune system in a chemostat by Mengshi Shu, Rui Fu, Wendi Wang

    Published 2017-09-01
    “…Clustered regularly interspaced short palindromic repeats (CRISPRs) along with Cas proteins are a widespread immune system across bacteria and archaea. …”
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    Article
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    Current Status of Research, Regulations, and Future Challenges for CRISPR Gene-Editing in Crop Improvement by Sadikshya Sharma, Seonghee Lee, Heqiang Huo

    Published 2019-09-01
    “… Recently, new plant-breeding technology such as CRISPR gene editing has provided the potential to substantially improve crop breeding in agriculture. …”
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    Article
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    Simple Meets Single: The Application of CRISPR/Cas9 in Haploid Embryonic Stem Cells by Zixi Yin, Lingyi Chen

    Published 2017-01-01
    “…The CRISPR/Cas9 system provides a powerful method for the genetic manipulation of the mammalian genome, allowing knockout of individual genes as well as the generation of genome-wide knockout cell libraries for genetic screening. …”
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    Article
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    Current Status of Research, Regulations, and Future Challenges for CRISPR Gene-Editing in Crop Improvement by Sadikshya Sharma, Seonghee Lee, Heqiang Huo

    Published 2019-09-01
    “… Recently, new plant-breeding technology such as CRISPR gene editing has provided the potential to substantially improve crop breeding in agriculture. …”
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    Article
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    iPSCs: A Minireview from Bench to Bed, including Organoids and the CRISPR System by Andrés Javier Orqueda, Carla Alejandra Giménez, Federico Pereyra-Bonnet

    Published 2016-01-01
    “…Here, we analyze the current state, opportunities, and challenges of iPSCs from bench to bed, including organoids and the CRISPR system.…”
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    A systematic screening assay identifies efficient small guide RNAs for CRISPR activation by Elin Arvidsson, Diana Duarte Lobo, Diana Duarte Lobo, Ermelinda Sabarese, Fabio Duarte, Rui Jorge Nobre, Rui Jorge Nobre, Rui Jorge Nobre, Luis Quintino, Cecilia Lundberg

    Published 2025-01-01
    “…CRISPR-mediated gene activation (CRISPRa) encompasses a growing field of biotechnological approaches with exciting implications for gene therapy. …”
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    Induced protein expression in Leptospira spp. and its application to CRISPR/Cas9 mutant generation by L. G. V. Fernandes, A. L. T. O. Nascimento, J. E. Nally

    Published 2025-02-01
    “…Bovine leptospirosis causes substantial financial losses due to abortion, stillbirths, and suboptimal reproductive performance. The advent of the CRISPR/Cas9 system has marked a turning point in genetic manipulation, with applications across multiple Leptospira species. …”
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    Engineered CRISPR-Cas9 for Streptomyces sp. genome editing to improve specialized metabolite production by Duck Gyun Kim, Boncheol Gu, Yujin Cha, Jeonghan Ha, Yongjae Lee, Gahyeon Kim, Byung-Kwan Cho, Min-Kyu Oh

    Published 2025-01-01
    “…Abstract The CRISPR-Cas9 system has frequently been used for genome editing in Streptomyces; however, cytotoxicity, caused by off-target cleavage, limits its application. …”
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