Clinical and Laboratory Diagnosis of Buruli Ulcer Disease: A Systematic Review by Samuel A. Sakyi, Samuel Y. Aboagye, Isaac Darko Otchere, Dorothy Yeboah-Manu

“…Background. Buruli ulcer (BU) is a necrotizing cutaneous infection caused by Mycobacterium ulcerans. …”
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Evidences of the Low Implication of Mosquitoes in the Transmission of Mycobacterium ulcerans, the Causative Agent of Buruli Ulcer by Rousseau Djouaka, Francis Zeukeng, Jude Daiga Bigoga, David N’golo Coulibaly, Genevieve Tchigossou, Romaric Akoton, Sylla Aboubacar, Sodjinin Jean-Eudes Tchebe, Clavella Nantcho Nguepdjo, Razack Adeoti, Innocent Djegbe, Manuele Tamo, Wilfred Fon Mbacham, Solange E. Kakou-Ngazoa, Anthony Ablordey

“…Background. Buruli ulcer (BU) continues to be a serious public health threat in wet tropical regions and the mode of transmission of its etiological agent, Mycobacterium ulcerans (MU), remains poorly understood. …”
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Subcutaneous Granulomatous Inflammation due to Basidiobolomycosis: Case Reports of 3 Patients in Buruli Ulcer Endemic Areas in Benin by Luc V. C. Brun, Jean Jacques Roux, Ghislain E. Sopoh, Julia Aguiar, Miriam Eddyani, Wayne M. Meyers, Dirk Stubbe, Marie T. Akele Akpo, Françoise Portaels, Bouke C. de Jong

“…We report on three patients misdiagnosed as suffering from Buruli ulcer, who did not respond to Buruli treatment. …”
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Basidiobolomycosis Simulating a Mycobacterium ulcerans Infection in a Togolese Rural Child by Bayaki Saka, Waguena Gnassingbe, Garba Mahamadou, Sefako Akakpo, Julienne Teclessou, Aurel Abilogun-Chokki, Abas Mouhari-Toure, Koussake Kombate, Palokinam Pitché

“…Examination of other organs was normal. The diagnosis of Buruli ulcer was evoked first; the search for Mycobacterium ulcerans by polymerase chain reaction was negative. …”
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Co-creation of a gender responsive TB intervention in Nigeria: a researcher-led collaborative study by Chukwuebuka Ugwu, Oluwatoyosi Adekeye, Beate Ringwald, Rachael Thomson, Obioma Chijioke-Akaniro, Chukwuma Anyaike, S Bertel Squire, John Bimba, Tom Wingfield

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Mycobacterium ulcerans and Mycobacterium marinum: Pathogenesis, Diagnosis and Treatment by Loh Teng-Hern Tan, Pendru Raghunath, Long Chiau Ming, Jodi Woan-Fei Law

“…In term pathogenesis, prolonged cell exposure to exotoxin mycolactone produced by M. ulcerans could lead to Buruli ulcer. Meanwhile, like most pathogenic mycobacteria, M. marinum evades the host immune responses by invading and replicating inside host cells and it is capable of modulating host immune responses. …”
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Susceptibility Profiles of Mycobacterium ulcerans Isolates to Streptomycin and Rifampicin in Two Districts of the Eastern Region of Ghana by Enid Owusu, Mercy Jemima Newman, Nana Konama Kotey, Amos Akumwena, Elizabeth Bannerman

“…Assessing resistance profiles of pathogens constitutes an essential surveillance tool in the epidemiology and control of infectious diseases, including Buruli ulcer (BU) disease. With the successful definitive management of BU using rifampicin and streptomycin, little attention had been paid to monitoring emergence of resistant Mycobacterium ulcerans (M. ulcerans) isolates in endemic communities. …”
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The current status of neglected tropical diseases in Japan: A scoping review. by Yuriko Harada, Hanako Iwashita, Taeko Moriyasu, Sachiyo Nagi, Nobuo Saito, Mariko Sugawara-Mikami, Kota Yoshioka, Rie Yotsu, Japan NTD Study Group

“…Our findings revealed the transmission of alveolar echinococcosis, Buruli ulcer, Chagas disease, dengue, foodborne trematodiases, mycetoma, scabies, and soil-transmitted helminthiasis as well as occurrence of snakebites within Japan. …”
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The Mycobacterium ulcerans toxin mycolactone causes destructive Sec61-dependent loss of the endothelial glycocalyx and vessel basement membrane to drive skin necrosis by Louise Tzung-Harn Hsieh, Belinda S Hall, Jane Newcombe, Tom A Mendum, Sonia Santana Varela, Yagnesh Umrania, Michael J Deery, Wei Q Shi, Josué Diaz-Delgado, Francisco J Salguero, Rachel E Simmonds

“…The drivers of tissue necrosis in Mycobacterium ulcerans infection (Buruli ulcer disease) have historically been ascribed solely to the directly cytotoxic action of the diffusible exotoxin, mycolactone. …”
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