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501
An Improved HM-SAC-CA Algorithm for Mobile Robot Path Planning in Unknown Complex Environments
Published 2025-01-01“…The staged incentive mechanism uses both the sparse reward function and the posture reward function in stages to reduce the blindness of exploration during training and accelerate the training learning process. …”
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502
Visual prognosis after standardized classification in patients with ocular trauma
Published 2009-12-01“…<strong>Background</strong>: Ocular traumas are a common cause of visual deficiency, mainly of monocular blindness. <strong><br />Objective:</strong> To compare the visual prognosis after the standardized classification of visual trauma. …”
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503
Targeting Inflammation in Emerging Therapies for Genetic Retinal Disease
Published 2013-01-01“…Despite this, numerous interventional studies, particularly targeting the complement system, are underway with the promise of novel therapeutic strategies for these important blinding conditions.…”
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504
Oral and intestinal manifestations of giant cell arteritis
Published 2025-01-01“…GCA typically affects large- and medium-sized arteries and is classically associated with cranial manifestations of ischaemia, such as headaches (notably in the temporal region), jaw claudication and visual symptoms that can lead to blindness. Extracranial symptoms are less frequently reported and are related to involvement of the thoracic and abdominal aorta and its main branches. …”
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505
Quantitative Multiparameter Evaluation of Vacuoles in Intraocular Lenses Employing a High-Magnification Digital Microscopy Method
Published 2019-01-01“…This unwanted scatter is of particular concern for patients viewing bright light in reduced-light conditions such as when driving at night, as the scattered light toward the retina can cause temporary blindness. In this study, we have developed and implemented an accurate test methodology based on a high-magnification digital microscopy approach for quantitative multiparameter evaluation and classification of IOL vacuoles depending on their critical optical characteristics including vacuole size, density, shape, and orientation within the IOL material. …”
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506
Monitoring ocular disease via optical nanostructures potentially applicable to corneal contact lens products
Published 2024-06-01“…Abstract Ocular diseases can cause vision problems or even blindness if they are not detected early. Some ocular diseases generate irregular physical changes in the eye; therefore, reliable diagnostic technology for continuous monitoring of the eye is an unmet clinical need. …”
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507
Automatic Screening and Grading of Age-Related Macular Degeneration from Texture Analysis of Fundus Images
Published 2016-01-01“…Age-related macular degeneration (AMD) is a disease which causes visual deficiency and irreversible blindness to the elderly. In this paper, an automatic classification method for AMD is proposed to perform robust and reproducible assessments in a telemedicine context. …”
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508
Targeting Herpetic Keratitis by Gene Therapy
Published 2012-01-01“…Viral infections such as herpetic keratitis caused by herpes simplex virus 1 (HSV-1) can cause serious complications that may lead to blindness. Recurrence of the disease is likely and cornea transplantation, therefore, might not be the ideal therapeutic solution. …”
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509
Diabetic Retinopathy Detection Using Local Extrema Quantized Haralick Features with Long Short-Term Memory Network
Published 2021-01-01“…Lack of early detection and treatment can lead to total blindness of the diseased eyes. Recently, numerous researchers have attempted producing automatic diabetic retinopathy detection techniques to supplement diagnosis and early treatment of diabetic retinopathy symptoms. …”
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510
Childhood Vitamin A Capsule Supplementation Coverage in Nigeria: A Multilevel Analysis of Geographic and Socioeconomic Inequities
Published 2010-01-01“…Vitamin A deficiency (VAD) is a huge public health burden among preschool-aged children in sub-Saharan Africa, and is associated with a high level of susceptibility to infectious diseases and pediatric blindness. We examined the Nigerian national vitamin A capsule (VAC) supplementation program, a short-term cost-effective intervention for prevention of VAD-associated morbidity for equity in terms of socioeconomic and geographic coverage. …”
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511
Purification and Characterization of a Mitogenic Lectin from Cephalosporium, a Pathogenic Fungus Causing Mycotic Keratitis
Published 2010-01-01“…Ophthalmic mycoses caused by infectious fungi are being recognized as a serious concern since they lead to total blindness. Cephalosporium is one amongst several opportunistic fungal species implicated in ophthalmic infections leading to mycotic keratitis. …”
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512
Cyclooxygenase Inhibitor Associated with Carboplatin in Treatment of Metastatic Nasal Carcinoma in Dog
Published 2014-01-01“…A 10-year-old, intact male, pinscher was presented with unilateral bloodstained nasal discharge, sneezing, dyspnea, zygomatic arch deformity, submandibular lymph node increase, blindness in right eye, and exophthalmia. After clinical examination, it was found that the animal presented with upper respiratory tract dyspnea origin, possibly caused by an obstructive process. …”
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513
Perspectives and Limitations of Mesenchymal Stem Cell–Based Therapy for Corneal Injuries and Retinal Diseases
Published 2025-01-01“…If the immune privilege of the eye is interrupted and the regulatory mechanisms are not sufficiently effective, the eye disease can progress and result in worsening of vision or even blindness. In such cases, external immunotherapeutic interventions are needed. …”
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514
Effect Improved for High-Dimensional and Unbalanced Data Anomaly Detection Model Based on KNN-SMOTE-LSTM
Published 2020-01-01“…This model can continuously filter out and securely generate samples to improve the performance of the model through kNN discriminant classifier and avoid the blindness and limitations of the SMOTE algorithm in generating new samples. …”
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515
Does Cataract Surgery Improve the Progression of Age-Related Macular Degeneration? A Meta-Analysis
Published 2020-01-01“…Cataract and age-related macular degeneration (AMD) are the common causes of blindness in the elderly. Although cataract surgery is the most effective treatment for cataract, some clinicians suspect that such interventions may accelerate the progression of AMD. …”
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516
Development and Validation of Chlamydia muridarum Mouse Models for Studying Genital Tract Infection Pathogenesis
Published 2025-02-01“…Chronic infections can result in severe consequences such as trachoma-induced blindness, ectopic pregnancy, and infertility. While intravaginal inoculation of C. muridarum mimics the natural route of sexual transmission between individuals, transcervical inoculation allows the organisms to directly infect endometrial epithelial cells without interference from host responses triggered by chlamydial contact or infection of vaginal and cervical cells. …”
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517
Fundus Images-Based Detection and Grading of Macular Edema Using Robust Macula Localization
Published 2018-01-01“…Macular disorders are the group of diseases that damage the macula, resulting in blurred vision or even blindness. Macular edema (ME), one of the most common types of macular disorder, is caused by fluid accumulation beneath the macula. …”
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518
Association of Lumican Gene with Susceptibility to Pathological Myopia in the Northern Han Ethnic Chinese
Published 2009-01-01“…Pathological myopia is a severe hereditary ocular disease leading to blindness. It is urgent and very important to find the pathogenesis and therapy for this disease. …”
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519
A comprehensive review on early detection of drusen patterns in age-related macular degeneration using deep learning models
Published 2025-02-01“…Age-related Macular Degeneration (AMD) is a leading cause of visual impairment and blindness that affects the eye from the age of fifty-five and older. …”
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520
Designing of Aplikasi Pendamping Diabetes (Si-PenDi) as a Control Tool for Type 2 Diabetes Mellitus Patients
Published 2024-04-01“…Diabetes Mellitus is known as the mother of other diseases such as cardiovascular disease, kidney failure, and blindness. Indonesia ranks 5th in the world in terms of the number of Diabetes Mellitus sufferers in 2014. …”
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