Does severe mucositis impair oncological outcome in head and neck cancer patients? A pooled analysis of two prospective studies with long-term follow-up by Tanja Sprave, Jörg Sahlmann, Andreas R. Thomsen, Diana Klein, Henning Schäfer, Raluca Stoian, Vivek Verma, Anca-Ligia Grosu, Elsa Beatriz Monroy Ordonez

Get full text

Additive Value of Biomarkers and Echocardiography to Stratify the Risk of Death in Heart Failure Patients with Reduced Ejection Fraction by Calogero Falletta, Francesco Clemenza, Catherine Klersy, Valentina Agnese, Diego Bellavia, Gabriele Di Gesaro, Chiara Minà, Giuseppe Romano, Pier Luigi Temporelli, Frank Lloyd Dini, Andrea Rossi, Claudia Raineri, Annalisa Turco, Egidio Traversi, Stefano Ghio

Get full text

Prognostic Impact of COVID-19 Inflammation Score Response: A Sub-Group Analysis on Critically Ill Patients of the RuxCoFlam Trial by Manfred Weiss, Jakob Hammersen, Sebastian Rudolphi, Isabell Formann, Karl Träger, Frank G. Rücker, Beate Grüner, Andreas Allgöwer, Sebastian Birndt, Christian Fabisch, Andreas Hochhaus, Konstanze Döhner, Paul La Rosée, Frank Stegelmann

Get full text

Encouragement of patients’ self-management in primary care for the prevention of cardiovascular diseases (DECADE): protocol for a cluster randomised controlled trial by Hanna Hardt, Antje Bergmann, Iris Tinsel, Maja Börger, Melanie Kamp, Thomas Kloppe, Anja Rakebrandt, Tina Görbing, Susanne Kutter, Henna Riemenschneider

Get full text

Professional and academic pre-qualifications, career preferences and aspirations in working as a rural doctor by Carla Schröpel, Teresa Festl-Wietek, Anne Herrmann-Werner, Tim Wittenberg, Marina Pumptow, Sabine C. Herpertz, Andrea Heinzmann, Katrin Schüttpelz-Brauns, Tobias Maria Boeckers, Stephan Zipfel, Stephan Zipfel, Rebecca Erschens

Get full text

Retinoic acid-induced 2 deficiency impairs genomic stability in breast cancer by Lena Boettcher, Sarah Greimeier, Kerstin Borgmann, Shabbir S. Mughal, Bernhard Ellinger, Kai Bartkowiak, Bernd Zobiak, Antonio V. Failla, Pascal Steffen, Ellen Claus, Katharina Besler, Christopher Buccitelli, Violetta Schaaf, Ann-Kathrin Ozga, Simona Parretta, Svenja Schneegans, Wael Y. Mansour, Jan O. Korbel, Hartmut Schlueter, Benedikt Brors, Klaus Pantel, Harriet Wikman, Stefan Werner

Get full text

Regional variations in healthcare in people living with dementia in Germany: protocol for a mixed-methods study by Daniela Koller, Ursula Marschall, Dirk Horenkamp-Sonntag, Enno Swart, Martin Heinze, Sebastian von Peter, Michael Hauptmann, Daniela Gesell, Bernhard Michalowsky, Hannah Julia Scheibner, Denise Kubat, Johannes Meixner, Moritz Platen, Cordula Riederer, Jennifer Schroth, Lea Weirauch, Volker Dahling

Get full text

Lupus nephritis and U1-RNP-antibodies are associated with low bone mineral density and osteoporosis in patients with systemic lupus erythematosus: baseline findings in a sub-cohort... by Edgar Wiebe, Elisa Celine Schilling, Dörte Huscher, Andriko Palmowski, Zhivana Boyadzhieva, Sandra Hermann, Burkhard Muche, Mirella Lopez Picazo, Gerhard Krönke, Falk Hiepe, Tobias Alexander, Frank Buttgereit

Get full text

Fall sensors, home emergency system, and social service for ≥ 75-year-olds living at home - a matched control intervention study by Jan C. Zoellick, Sonia Lech, Julie L. O’Sullivan, Eva Jansen, Juliana Supplieth, Ronny Kuhnert, Ulrike Grittner, Johanna Schuster

Get full text

Hypoxic-ischemic brain injury in pig after cardiac arrest – A new histopathological scoring system for non-specialists by Miriam Renz, Pascal Siegert, Roman Paul, Adina Lepadatu, Petra Leukel, Katrin Frauenknecht, Andrea Urmann, Johanna Hain, Katja Mohnke, Alexander Ziebart, Anja Harder, Robert Ruemmler

Get full text

Respiratory long COVID in aged hamsters features impaired lung function post-exercise with bronchiolization and fibrosis by Laura Heydemann, Małgorzata Ciurkiewicz, Theresa Störk, Isabel Zdora, Kirsten Hülskötter, Katharina Manuela Gregor, Lukas Mathias Michaely, Wencke Reineking, Tom Schreiner, Georg Beythien, Asisa Volz, Tamara Tuchel, Christian Meyer zu Natrup, Lisa-Marie Schünemann, Sabrina Clever, Timo Henneck, Maren von Köckritz-Blickwede, Dirk Schaudien, Karl Rohn, Klaus Schughart, Robert Geffers, Mika K. Kaneko, Yukinari Kato, Carina Gross, Georgios Amanakis, Andreas Pavlou, Wolfgang Baumgärtner, Federico Armando

Get full text

Smoking increases risk of complication after musculoskeletal surgery by Leyla Tümen, Lena Pollmann-Schweckhorst, Regina Breinbauer, Mohammad M. Hammour, Romina H. Aspera-Werz, Gunnar Blumenstock, Tina Histing, Maximilian M. Menger, Sabrina Ehnert, Andreas Nüssler

Get full text

TRIPOD+AI statement: updated guidance for reporting clinical prediction models that use regression or machine learning methods: a Korean translation by Gary S. Collins, Karel G. M. Moons, Paula Dhiman, Richard D. Riley, Andrew L. Beam, Ben Van Calster, Marzyeh Ghassemi, Xiaoxuan Liu, Johannes B. Reitsma, Maarten van Smeden, Anne-Laure Boulesteix, Jennifer Catherine Camaradou, Leo Anthony Celi, Spiros Denaxas, Alastair K. Denniston, Ben Glocker, Robert M. Golub, Hugh Harvey, Georg Heinze, Michael M. Hoffman, André Pascal Kengne, Emily Lam, Naomi Lee, Elizabeth W. Loder, Lena Maier-Hein, Bilal A. Mateen, Melissa D. McCradden, Lauren Oakden-Rayner, Johan Ordish, Richard Parnell, Sherri Rose, Karandeep Singh, Laure Wynants, Patricia Logullo

Get full text

Recruiting patients into a healthcare services trial: lessons learned from a feasibility study to investigate a patient-oriented navigation intervention for age-associated diseases by Kathrin Gödde, Hella Fügemann, Ulrike Grittner, Raphael Kohl, Andreas Meisel, Thomas Reinhold, Nina Rieckmann, Susanne Schnitzer, P. Markus Deckert, Nikolaj Frost, Christian H. Nolte, Stephan J. Schreiber, Ute Goerling, Christine Holmberg

Get full text

The effect of iron deficiency on cardiac resynchronization therapy: results from the RIDE‐CRT Study by Philipp Lacour, Phi Long Dang, Daniel Armando Morris, Abdul Shokor Parwani, Wolfram Doehner, Franziska Schuessler, Felix Hohendanner, Frank R. Heinzel, Andrea Stroux, Carsten Tschoepe, Wilhelm Haverkamp, Leif‐Hendrik Boldt, Burkert Pieske, Florian Blaschke

Get full text

Personalised, GIS-based counselling to promote habitual walking in mobility-limited and chronically ill older adults: protocol of the MOBITEC-Routes randomised controlled trial by Timo Hinrichs, René Schilling, Alexandros Sofios, Denis Infanger, Luisa Prechtl, Nora Stauffer, Viviane Eichenberger, Eleftheria Giannouli, Taina Rantanen, Erja Portegijs, Corina Schuster-Amft, Anna Mai, Arno Schmidt-Trucksäss, Christina Röcke, Robert Weibel

Get full text

Treating nightmares in post-traumatic stress disorder with the α-adrenergic agents clonidine and doxazosin: protocol for a phase II randomised, double-blind, placebo-controlled par... by Christian Schmahl, Jürgen Gallinat, Andreas J Fallgatter, Christian Otte, Stefan Roepke, Robert Roehle, Nikola Schoofs, Kathlen Priebe, Felix Wuelfing, Tolou Maslahati, Katharina Stieglbauer, Sarah Biedermann, Ingo Schaefer, Thomas Ethofer, Bernd Hanewald, Christoph Mulert, Stefanie Koglin

Get full text

Clinical improvements after endoscopic lung volume reduction with valves in patients with advanced emphysema and a 6-min walk test ≤140 m at baseline by Jacopo Saccomanno, Lara Kilic, Thomas Sgarbossa, Konrad Neumann, Franz Stanzel, Angelique Holland, Christian Grah, Wolfgang Gesierich, Joanna Krist, Joachim H. Ficker, Stephan Eggeling, Stefan Andreas, Bernd Schmidt, Stephan Eisenmann, Björn Schwick, Karl-Josef Franke, Andreas Fertl, Martin Witzenrath, Ralf-Harto Hübner

Get full text

sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early‐stage Alzheimer's disease and associate with neuronal injury markers by Marc Suárez‐Calvet, Gernot Kleinberger, Miguel Ángel Araque Caballero, Matthias Brendel, Axel Rominger, Daniel Alcolea, Juan Fortea, Alberto Lleó, Rafael Blesa, Juan Domingo Gispert, Raquel Sánchez‐Valle, Anna Antonell, Lorena Rami, José L Molinuevo, Frederic Brosseron, Andreas Traschütz, Michael T Heneka, Hanne Struyfs, Sebastiaan Engelborghs, Kristel Sleegers, Christine Van Broeckhoven, Henrik Zetterberg, Bengt Nellgård, Kaj Blennow, Alexander Crispin, Michael Ewers, Christian Haass

Get full text

Evaluation of a validated questionnaire to assess the need for prevention or rehabilitation by preventive health examinations: a cross-sectional study of German employees aged 45 t... by Linda Kalski, Linda Kalski, Tilman J. Pulst Caliman, Franziska Greiß, Athanasios Karathanos, Lorena Hafermann, Laura Völkel, Laura Völkel, Charleen Pächter, Charleen Pächter, Carolin Herrmann, Maja A. Hofmann, Maja A. Hofmann, Bernd Wolfarth, Bernd Wolfarth

Get full text