Techno-economic feasibility of olive residue-based biohubs for marine biofuel production: A capability-sensitive and context-specific approach in the Mediterranean region by Sivaramakrishnan Chandrasekaran, Alfonso M. Vidal, Eulogio Castro, Patricia Osseweijer, John Posada

“…This study aims to design and evaluate the techno-economic feasibility of socially just and context-specific biohubs for producing marine biofuels based on olive residues with hydrothermal liquefaction (HTL) in Spain, using existing infrastructures. …”
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Single-nucleus RNA sequencing reveals a preclinical model for the most common subtype of glioblastoma by Laura García-Vicente, María Martínez-Fernández, Michael Borja, Vanessa Tran, Andrea Álvarez-Vázquez, Raquel Flores-Hernández, Yuxin Ding, Raúl González-Sánchez, Alejandro Granados, Erin McGeever, Yang-Joon Kim, Angela Detweiler, Honey Mekonen, Sheryl Paul, Angela O. Pisco, Norma F. Neff, Arantxa Tabernero

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Microbial dynamics and pulmonary immune responses in COVID-19 secondary bacterial pneumonia by Natasha Spottiswoode, Alexandra Tsitsiklis, Victoria T. Chu, Hoang Van Phan, Catherine DeVoe, Christina Love, Rajani Ghale, Joshua Bloomstein, Beth Shoshana Zha, Cole P. Maguire, Abigail Glascock, Aartik Sarma, Peter M. Mourani, Katrina L. Kalantar, Angela Detweiler, Norma Neff, Sidney C. Haller, COMET Consortium, Joseph L. DeRisi, David J. Erle, Carolyn M. Hendrickson, Kirsten N. Kangelaris, Matthew F. Krummel, Michael A. Matthay, Prescott G. Woodruff, Carolyn S. Calfee, Charles R. Langelier

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Simultaneous detection of pathogens and antimicrobial resistance genes with the open source, cloud-based, CZ ID platform by Dan Lu, Katrina L. Kalantar, Abigail L. Glascock, Victoria T. Chu, Estella S. Guerrero, Nina Bernick, Xochitl Butcher, Kirsty Ewing, Elizabeth Fahsbender, Olivia Holmes, Erin Hoops, Ann E. Jones, Ryan Lim, Suzette McCanny, Lucia Reynoso, Karyna Rosario, Jennifer Tang, Omar Valenzuela, Peter M. Mourani, Amy J. Pickering, Amogelang R. Raphenya, Brian P. Alcock, Andrew G. McArthur, Charles R. Langelier

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HistomicsTK: A Python toolkit for pathology image analysis algorithms by Fattaneh Pourakpour, Ákos Szölgyén, Ramin Nateghi, David A Gutman, David Manthey, Lee AD Cooper

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A developmental biliary lineage program cooperates with Wnt activation to promote cell proliferation in hepatoblastoma by Peng V. Wu, Matt Fish, Florette K. Hazard, Chunfang Zhu, Sujay Vennam, Hannah Walton, Dhananjay Wagh, John Coller, Joanna Przybyl, Maurizio Morri, Norma Neff, Robert B. West, Roel Nusse

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Mapping the nucleolar proteome reveals a spatiotemporal organization related to intrinsic protein disorder by Lovisa Stenström, Diana Mahdessian, Christian Gnann, Anthony J Cesnik, Wei Ouyang, Manuel D Leonetti, Mathias Uhlén, Sara Cuylen‐Haering, Peter J Thul, Emma Lundberg

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Multicilia dynamically transduce Sonic Hedgehog signaling to regulate choroid plexus functions by Suifang Mao, Rui Song, Shibo Jin, Song Pang, Aleksandra Jovanovic, Adam Zimmerman, Peng Li, Xinying Wu, Michael F. Wendland, Kerry Lin, Wei-Chi Chen, Semil P. Choksi, Gang Chen, Michael J. Holtzman, Jeremy F. Reiter, Ying Wan, Zhenyu Xuan, Yang K. Xiang, C. Shan Xu, Srigokul Upadhyayula, Harald F. Hess, Lin He

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Response to “Assessing the outcomes of malaria intermittent preventive treatment during pregnancy on child growth trajectories” by Jade Benjamin-Chung, Yanwei Tong, Michelle E. Roh, Prasanna Jagannathan

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A Global Collaborative Comparison of SARS-CoV-2 Antigenicity Across 15 Laboratories by Polina Brangel, Sina Tureli, Barbara Mühlemann, Nicole Liechti, Daniel Zysset, Olivier Engler, Isabel Hunger-Glaser, Ioana Ghiga, Giada Mattiuzzo, Isabella Eckerle, Meriem Bekliz, Annika Rössler, Melanie M. Schmitt, Ludwig Knabl, Janine Kimpel, Luis Fernando Lopez Tort, Mia Ferreira de Araujo, Any Caroline Alves de Oliveira, Braulia Costa Caetano, Marilda Mendonça Siqueira, Matthias Budt, Jean-Marc Gensch, Thorsten Wolff, Tarteel Hassan, Francis Amirtharaj Selvaraj, Tandile Hermanus, Prudence Kgagudi, Carol Crowther, Simone I. Richardson, Jinal N. Bhiman, Penny L. Moore, Samuel M. S. Cheng, John K. C. Li, Leo L. M. Poon, Malik Peiris, Victor M. Corman, Christian Drosten, Lilin Lai, Taweewun Hunsawong, Kamonthip Rungrojcharoenkit, Jindarat Lohachanakul, Alex Sigal, Khadija Khan, Volker Thiel, G. Tuba Barut, Nadine Ebert, Anna Z. Mykytyn, Irene Owusu Donkor, James Odame Aboagye, Prince Adom Nartey, Maria D. Van Kerkhove, Jane Cunningham, Bart L. Haagmans, Mehul S. Suthar, Derek Smith, Lorenzo Subissi

“…Live virus isolates (source: WHO BioHub or individual labs) or spike plasmids (individual labs) for pseudovirus production were used to perform neutralisation assays using the same serum panels. …”
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Genome concentration limits cell growth and modulates proteome composition in Escherichia coli by Jarno Mäkelä, Alexandros Papagiannakis, Wei-Hsiang Lin, Michael Charles Lanz, Skye Glenn, Matthew Swaffer, Georgi K Marinov, Jan M Skotheim, Christine Jacobs-Wagner

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Mapping the Simultaneously Accessible and ssDNA-Containing Genome With KAS-ATAC Sequencing by Georgi Marinov, William Greenleaf

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Physical inactivity exacerbates pathologic inflammatory signalling at the single cell level in patients with systemic lupusResearch in context by Sarah L. Patterson, Hoang Van Phan, Chun Jimmie Ye, Cristina Lanata, Sebastián Cruz González, Joonsuk Park, Lindsey A. Criswell, Kamil E. Barbour, Jinoos Yazdany, Maria Dall’Era, Marina Sirota, Patricia Katz, Charles R. Langelier

“…Funding: This work was supported by the US National Institutes of Health (NIH) (R01 AR069616, K23HL138461-01A1, K23AT011768) the US CDC (U01DP0670), and the CZ Biohub.…”
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Decoding bioactive signals of the RNA secretome: the cell-free messenger RNA catalogue by Rhys E. De Sota, Stephen R. Quake, John J. Sninsky, Shusuke Toden

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Correlating disordered activation domain ensembles with gene expression levels by Eduardo Flores, Aleah R. Camacho, Estefania Cuevas-Zepeda, Mary B. McCoy, Feng Yu, Max V. Staller, Shahar Sukenik

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Assessing global preparedness for the next pandemic: development and application of an Epidemic Preparedness Index by Ben Oppenheim, Mark Gallivan, Nita K Madhav, Naor Brown, Volodymyr Serhiyenko, Nathan D Wolfe, Patrick Ayscue

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Conformational ensembles for protein structure prediction by Jiaan Yang, Wen Xiang Cheng, Peng Zhang, Gang Wu, Si Tong Sheng, Junjie Yang, Suwen Zhao, Qiyue Hu, Wenxin Ji, Qiong Shi

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Targeted CRISPR screens reveal genes essential for Cryptosporidium survival in the host intestine by Lucy C. Watson, Katarzyna A. Sala, Netanya Bernitz, Lotta Baumgärtel, Mitchell A. Pallett, N. Bishara Marzook, Lorian Cobra Straker, Duo Peng, Lucy Collinson, Adam Sateriale

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Semaphorin7A patterns neural circuitry in the lateral line of the zebrafish by Agnik Dasgupta, Caleb C Reagor, Sang Peter Paik, Lauren M Snow, Adrian Jacobo, AJ Hudspeth

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Unified bursting strategies in ectopic and endogenous even-skipped expression patterns by Augusto Berrocal, Nicholas C Lammers, Hernan G Garcia, Michael B Eisen

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