Principles, barriers and enablers to agroecological animal production systems: a qualitative approach based on five case studies by B. Dumont, C. Barlagne, P. Cassart, J.E. Duval, A. Fanchone, J-L. Gourdine, O. Huguenin-Elie, Y. Kazakova, J. Klötzli, A. Lüscher, E. Oteros-Rozas, D. Pomies, M.G. Rivera Ferre, W.A.H. Rossing, V. Stefanova, A. Swartebroeckx, C. Zagaria

“…Inadequate infrastructure and lack of technology were frequently reported as barriers to agroecological transitions. Policy needs to go beyond the mere support of agroecological practices on livestock farms and adopt a systems approach looking downstream and upstream if it is to enable a large-scale agroecological transition with EU public policies. …”
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TC2N maintains stem cell-like characteristics to accelerate lung carcinogenesis by blockade of dual specificity protein phosphatase 3 by Jing Gu, Yang-fan Lv, Ji-ying Xia, Fu-hai Bai, Ji Gong, Guang-qiang Pan, Bo Liu, Lu Huang, Qiao-nan Guo, Xiang-lin Hao

“…In previous studies, we have uncovered the oncogenic role and mechanisms of TC2N in lung cancer: TC2N achieves this by inhibiting the p53 signaling pathway and activating the NF-kappaB signaling pathway. Beyond that, its precise function in tumorigenesis is not fully understood. …”
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Utilization of partograph and associated factors among obstetric caregivers in Ethiopia: a systematic review and meta-analysis by Mulat Ayele, Eyob Shitie Lake, Gizachew Yilak, Getinet Kumie, Biruk Beletew Abate, Alemu Birara Zemariam, Befkad Derese Tilahun

“…Although a previous systematic review and meta-analysis (SRMA) had been conducted, they were not representative on a national level as they included a limited number of studies and did not evaluate the current prevalence of partograph utilization beyond July 2019. Since then, there have been inconsistent studies assessing the proportion of partograph utilization and its associated factors. …”
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Supporting primary care clinicians in caring for patients with alcohol use disorder: study protocol for Records for Alcohol Care Enhancement (RACE), a factorial four-arm randomized... by Kara M. Magane, Richard Saitz, Sarah Fielman, Marc R. LaRochelle, Christopher W. Shanahan, Christine A. Pace, Michael LaValley, Kaley Penington, Skylar Karzhevsky, Emily Hurstak

“…This four-arm factorial design randomized trial will assess whether population health management (PHM) and clinical care management (CCM) support for primary care providers (PCPs) are associated with improved AUD treatment engagement among their patients, beyond electronic health record (EHR) prompting and decision support alone. …”
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Appearance of green tea compounds in plasma following acute green tea consumption is modulated by the gut microbiome in mice by John D. Sterrett, Kevin D. Quinn, Katrina A. Doenges, Nichole M. Nusbacher, Cassandra L. Levens, Mike L. Armstrong, Richard M. Reisdorph, Harry Smith, Laura M. Saba, Kristine A. Kuhn, Catherine A. Lozupone, Nichole A. Reisdorph

“…Overall, we describe a novel workflow for discovering relationships between individual food compounds and the composition of the gut microbiome.IMPORTANCEFoods contain thousands of unique and biologically important compounds beyond the macro- and micro-nutrients listed on nutrition facts labels. …”
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Symptoms of anxiety, depression, and post-traumatic stress disorder 6 weeks and 6 months after ICU: Six out of 10 survivors affected by E van der Merwe, L Stroud, G Sharp, N van Vuuren, M Mosola, T Fodo, F Paruk

“…A third of those affected developed these symptoms only beyond 6 weeks after hospital discharge. A potentially modifiable association with psychological symptoms was frightening memories of the ICU stay. …”
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Establishing a new human pneumococcal standard reference serum, MPRSS-01 by Joseph M. Antonello, Rocio D. Murphy, Chitrananda Abeygunawardana, Juliana C. Malinverni, Rajam Gowrisankar, Tina Green, Rebecca Greway, Jenna Schmauch, Adrienne Howlett, Cyrille J. Bonhomme, Katrina M. Nolan

“…With the development of next-generation PCVs, a new S. pneumoniae reference serum standard was needed to include serotypes beyond the existing 24 in 007sp. In this study, antibody concentrations to 33 pneumococcal serotypes were assigned in a new Merck Pneumococcal Reference Serum Standard (MPRSS-01) using the pneumococcal electrochemiluminescence assay, enabling V116 to maintain the link to the historical human pneumococcal standard reference serum while utilizing the new human pneumococcal reference serum.…”
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The appearance of scalp high‐frequency oscillations is associated with poor seizure control in pediatric epilepsy patients by Keisuke Maeda, Nami Hosoda, Himari Tsuboi, Honoka Naito, Chiaki Kudo, Junichi Fukumoto, Shiho Fujita, Naohiro Ichino, Keisuke Osakabe, Keiko Sugimoto, Shunta Yamaguchi, Naoko Ishihara

“…High‐frequency oscillations (HFOs), transient bursts of EEG activity with frequencies beyond 80 Hz, are a new and promising noninvasive epilepsy biomarker. …”
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'Which treatment do you believe you received?' A randomised blinding feasibility trial of spinal manual therapy by Javier Muñoz Laguna, Astrid Kurmann, Léonie Hofstetter, Emanuela Nyantakyi, Julia Braun, Lauren Clack, Heejung Bang, Mazda Farshad, Nadine E. Foster, Milo A. Puhan, Cesar A. Hincapié, the SALuBRITY Blinding Clinician Group

“…At study visit 1, 50% of participants in the active SMT arm (Bang BI: 0.50 [95% confidence interval (CI), 0.26 to 0.74]) and 37% in the placebo SMT arm (0.37 [95% CI, 0.10 to 0.63]) had a correct belief about their assigned intervention, beyond chance. At study visit 2, BIs were 0.36 (0.08 to 0.64) and 0.29 (0.01 to 0.57) for participants in the active and placebo SMT arms, respectively. …”
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Real-world experience with TTFields in glioma patients with emphasis on therapy usage by Claudius Jelgersma, Joan Alsolivany, Gülsüm Akkas, David Wasilewski, David Wasilewski, Bastian Gastl, Martin Misch, David Capper, David Capper, David Kaul, David Kaul, Lars Bullinger, Lars Bullinger, Peter Vajkoczy, Julia Onken, Julia Onken, Julia Onken

“…Linear regression found no predictors of usage, such as age, timing of therapy initiation, and duration or gender. 55% of patients continued TTFields beyond the first recurrence. Interestingly, no drop in usage rates was observed before tumor recurrence was communicated. …”
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Research involvement among undergraduate medical students in Bangladesh: a multicenter cross-sectional study by Mohammad Jahid Hasan, Salwa Islam, Hasnat Sujon, Fahmida Islam Chowdhury, Muna Islam, Mostak Ahmed, Mahbuba Shabnam, Mahbub Mayukh Rishad, Mohammad Nurunnabi, Md Marufur Rahman, Jannatul Fardous, Mir Susmita Zaman, Mir Paramita Zaman, Mir Ahsan Ali, Md Rabiual Awal, Taha Choudhury, Ahmed Ullah Shuvo, Sabrina Sultana, Tanjina Tabassum, Monjur Rahman, Anindita Das Barshan, Tamanna Tabassum, Md. Abdur Rafi, Sharmeen Yasmeen

“…Overall, 21.5% (n = 617) were actively participating in research beyond academic activities. Approximately 7% (n = 205) had undergone formal research training, and 6.5% (n = 187) had experience in publications in peer-reviewed journals as first authors or coauthors. …”
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Spatio-temporal dynamics of speleothem growth and glaciation in the British Isles by S. Panitz, S. Panitz, M. Rogerson, J. Longman, N. Scroxton, T. J. Lawson, T. C. Atkinson, V. Ersek, J. Baldini, L. Baldini, S. Umbo, M. A. Lone, G. M. Henderson, S. F. M. Breitenbach

“…In data-rich regions, such as northern England, ice dynamics are well replicated in the cave record, which provide additional evidence about the spatio-temporal distribution of permafrost dynamics. Beyond the Last Glacial Maximum, the distribution of speleothem dates across the British Isles offers the opportunity to improve chronological constraints on past ice sheet variability, with evidence for a highly dynamic Scottish ice sheet during the last glacial. …”
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Mapping Key Populations to Develop Improved HIV and AIDS Interventions: Multiphase Cross-Sectional Observational Mapping Study Using a District and City Approach by Pande Putu Januraga, Endang Lukitosari, Lanny Luhukay, Rizky Hasby, Aang Sutrisna

“…Developing strategies beyond identified hotspots, integrating mapping data into planning, and adopting a longitudinal approach to understand KP behavior over time are critical for effective HIV and AIDS prevention and control.…”
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Association of preoperative blood biomarkers with postoperative major adverse cardiac events and mortality in major orthopaedic surgery: a systematic review and meta-analysis by Lin Lu, Yi Ren, Zhen Hua, Yanxia Sun, Zhenghao Wen, Suzhen Zhou

“…This study aimed to assess the association between preoperative blood biomarkers and postoperative MACEs as well as all-cause mortality in patients undergoing major orthopaedic surgery.Design A systematic review and meta-analysis.Data sources PubMed, EMBASE, the Cochrane Controlled Trials Register and Cochrane Database of Systematic Reviews from inception to 20 October 2024 were searched.Eligibility criteria Observational or experimental studies reporting the correlation between preoperative blood biomarkers and postoperative MACEs—categorised as short-term (within 3 months) or long-term (beyond 3 months)—and all-cause mortality in patients undergoing major orthopaedic surgery.Data extraction and synthesis Data from studies reporting OR or HR and its 95% CI were pooled for analysis using random-effects model.Results 21 preoperative blood-based biomarkers from 80 studies with 226 468 patients were analysed. …”
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Effectiveness of Mobile Health–Based Gamification Interventions for Improving Physical Activity in Individuals With Cardiovascular Diseases: Systematic Review and Meta-Analysis of... by Tianzhuo Yu, Monica Parry, Tianyue Yu, Linqi Xu, Yuejin Wu, Ting Zeng, Xin Leng, Qian Tong, Feng Li

“…ConclusionsThis meta-analysis demonstrates that gamification interventions effectively promote PA in individuals with CVD, with effects persisting beyond the intervention period, indicating they are not merely novel effects caused by the game nature of gamification. …”
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New dimension in vortex electro-magnetic wave transmission with orbital angular momentum by Chao ZHANG, Yuanhe WANG

“…The statistical OAM vortex beams based on extrinsic OAM cannot constitute new dimensions beyond MIMO transmission and just belongs to the special case of multi-antenna MIMO systems which can generate the beams with helical phase front.…”
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A Magnetic Photocatalytic Composite Derived from Waste Rice Noodle and Red Mud by Qing Liu, Wanying Ying, Hailing Gou, Minghui Li, Ke Huang, Renyuan Xu, Guanzhi Ding, Pengyu Wang, Shuoping Chen

“…Under optimized conditions (pH = 8, carbon loading: 10 wt%), the CQDs/γ-Fe₂O₃ composite exhibited good photocatalytic performance against methylene blue, achieving a 97.6% degradation rate within 480 min and a degradation rate constant of 5.99 × 10⁻³ min⁻¹, significantly outperforming RM and commercial γ-Fe₂O₃ powder. Beyond methylene blue, this composite also effectively degraded common organic dyes, including malachite green, methyl violet, basic fuchsin, and rhodamine B, with particularly high efficiency against malachite green, reaching a degradation rate constant of 5.465 × 10⁻² min⁻¹. …”
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Al-Takrar Fii Daw'i Al-Dirasat Al-Uslubiyah Al-Haditsah by Aiyub Berdan

“…Stylistic studies extend beyond the observation of phonological, lexical, and grammatical elements to various levels of analysis. …”
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Biological arrow of time: emergence of tangled information hierarchies and self-modelling dynamics by Mikhail Prokopenko, Paul C W Davies, Michael Harré, Marcus G Heisler, Zdenka Kuncic, Geraint F Lewis, Ori Livson, Joseph T Lizier, Fernando E Rosas

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Dispersion modelling of particulate matter concentrations of sand product plants in a mineral complex by Y. Zehtab Yazdi, N. Mansouri, F. Atabi, H. Aghamohammadi

“…The results of the presented model indicated that 24-hour average concentrations of PM2.5, PM10, and total suspended particulates produced by mining activities were about 36, 183, and 690 µg/m3 in the working zone and less than 30, 100, and 400 µg/m3 beyond the mineral complex boundary, respectively. …”
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