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  1. 4521

    A conceptual framework for the instructional design of a Moodle-based e-learning course for mainstreaming informal master’s education outcomes into ESP teaching in a formal non-lin... by Larisa M. Galchuk

    Published 2024-12-01
    “…The research highlights the transformation of students’ informal cognitive activities from incidental and accidental learning to conscious and purposeful self-directed learning as a precondition for the successful implementation of a course on integrative mastering of an academic discipline in a formal context and beyond. This involves further development of the master’s systemic competencies and their deliberate transfer from formal to informal educational contexts while working with the learning resources of the lecture and project clusters within the thematic units of the online course. …”
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  2. 4522

    Improving the Biostability of Extra Virgin Olive Oil with Olive Fruit Extract During Prolonged Deep Frying by Taha Mehany, José M. González-Sáiz, Consuelo Pizarro

    Published 2025-01-01
    “…Moreover, sensory analysis revealed that positive attributes in EVOOs—such as fruity, bitter, and pungent notes—decreased significantly with increasing temperature and frying duration (<i>p</i> < 0.05). Beyond 210 °C/6 h, these attributes were rated at zero. …”
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  3. 4523

    Association between nutritional inflammation index and diabetic foot ulcers: a population-based study by Zhou Lin, Wanli Zhuang, Lei Wang, Weifeng Lan

    Published 2025-01-01
    “…Left of the inflection point, the relationship was negatively correlated. Beyond this point, further increased in ANLR no longer decrease DFU risk.ConclusionThe study not only proposed a new comprehensive indicator for predicting DFU for the first time but also specified the impact of ANLR on DFU risk. …”
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  4. 4524

    Être étranger dans 'La Nouvelle Héloïse' by Nathalie Ferrand

    Published 2024-11-01
    “…Yet there are many ways to be foreign in La Nouvelle Héloïse, and this issue extends far beyond that of mere nationalities. This great novel is populated by a multitude of foreign figures who correspond closely to those encountered by the historian Simona Cerutti in the course of her research for her book Étrangers: étude d’une condition d’incertitude dans une société d’Ancien Régime. …”
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  5. 4525

    Exploring coastal climate adaptation through storylines: Insights from cyclone Idai in Beira, Mozambique by Henrique M.D. Goulart, Panagiotis Athanasiou, Kees van Ginkel, Karin van der Wiel, Gundula Winter, Izidine Pinto, Bart van den Hurk

    Published 2025-01-01
    “…Combining both conditions increases impacts beyond 37 times. An adaptation strategy combining flood protection and accommodation measures reduces impacts by maximum 83%, while a seawall strategy reduces these by 10%. …”
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  6. 4526

    Therapeutic potential of brentuximab vedotin in breast cancer and lymphoma via targeted apoptosis and gene regulation by Abeer Ezzat, Mohga Shafiek, Shimaa Shawki, Shaimaa Abdel-Ghany, Mahmoud Nazih, Hussein Sabit

    Published 2025-01-01
    “…Additionally, the study investigated the potential of repurposing this drug for new therapeutic reasons, beyond its original indications. The study evaluates the cytotoxic effects of Brentuximab vedotin across five cell lines: normal human skin fibroblasts (HSF), three breast cancer cell lines (MCF-7, MDA-MB-231, and T-47D), and histiocytic lymphoma (U-937). …”
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  7. 4527

    MATHEMATICAL RATIONALE FOR CREATING AN APPLICATION FOR CONDUCTING RANDOM MEETINGS «COFFEE BREAK» by Vadym Ziuziun, Daniil Osoka

    Published 2024-12-01
    “…Expanding this practice to a broader societal level, CoffeeBreak is intended to provide individuals with the opportunity to network beyond their immediate professional circles. This research has established a conceptual system model and developed the mathematical frameworks necessary to support this type of meeting arrangement. …”
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  8. 4528

    Efficiency and safety of HAIC combined with lenvatinib and tislelizumab for advanced hepatocellular carcinoma with high tumor burden: a multicenter propensity score matching analys... by Zhonghua Zhao, Xiongying Jiang, Shiping Wen, Yanzhang Hao

    Published 2025-01-01
    “…PurposeThe present work focused on assessing whether hepatic arterial infusion chemotherapy (HAIC) combined with lenvatinib and tislelizumab was safe and effective on advanced hepatocellular carcinoma (HCC) showing high tumor burden.MethodsIn the present multicenter retrospective study, treatment-naive advanced HCC patients (BCLC stage C) showing high tumor burden (maximum diameter of intrahepatic lesion beyond 7 cm) treated with lenvatinib and tislelizumab with or without HAIC were reviewed for eligibility from June 2020 to June 2023. …”
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  9. 4529

    Assessment of the Impact of Floods to the Local Community in Nyarusiza Sub-County Kisoro District. by Murengezi, Innocent

    Published 2024
    “…When this tired or collected water reaches beyond the storage capacity limit, it ends up in flood. …”
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  10. 4530

    Assessing the Effect of Large Class Size and Pupils Academic Performance in Public Primary School in Rukungiri Municipality. by Kashumbusha, Robert

    Published 2024
    “…These included quality teaching and assessment suffering in large, lack of funding was perceived to impinge well beyond the classroom to the workplace and ultimately to the state of the economy, lack of appropriate value associated with teaching, school administration creating an environment that affects academic standards either positively or negatively. …”
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  11. 4531

    The Effect of Delegation of Responsibilities on Teachers’ Performance in Selected Secondary Schools in Kabale Municipality, Kabale District. by Seth, Ahumuza

    Published 2020
    “…They also develop the willingness to work beyond normal time, putting in more effort and have better attitudes towards their jobs. …”
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  12. 4532

    Severe primary graft failure: Are there lasting impacts? Analysis from the PHTS Database by Jennifer Conway, MD, Tara Pidborochynski, MSc, James K. Kirklin, MD, Ryan Cantor, PhD, Hong Zhao, PhD, Aryaz Sheybani, MD, Jacqueline Lamour, MD, Lakshmi Gokanapudy Hahn, MD, Leslie Collins, MD, Jessica Laks, MD, Darren H. Freed, MD, PhD

    Published 2025-02-01
    “…PGF was an independent predictor of overall graft loss (hazard ratios [HR] 4.7, p < 0.0001) and conditional survival to 30 days (HR 2.47, p < 0.0001) and 90 days (HR 1.6, p = 0.012) but not beyond 1 year. Conclusions: Severe PGF is an independent predictor of early mortality post-HTx but subsequently does not further impact long-term survival, overall risk of rejection, or CAV. …”
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  13. 4533

    Support Needs of Patients with Cushing’s Disease and Cushing’s Syndrome: Results of a Survey Conducted in Germany and the USA by Ilonka Kreitschmann-Andermahr, Sonja Siegel, Christa Gammel, Karen Campbell, Leslie Edwin, Agnieszka Grzywotz, Victoria Kuhna, Maria Koltowska-Häggström, Oliver Müller, Michael Buchfelder, Bernadette Kleist

    Published 2018-01-01
    “…In view of the high disease burden of CD/CS patients and long-term impaired quality of life, the present survey was conducted to gain information about subjective illness distress and patients’ specific needs in terms of supportive measures beyond medical interventions. Patients and Methods. …”
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  14. 4534
  15. 4535

    J-shaped association between dietary thiamine intake and the risk of cognitive decline in cognitively healthy, older Chinese individuals by Yuanyuan Zhang, Xianhui Qin, Chengzhang Liu, Chun Zhou, Mengyi Liu, Panpan He, Ziliang Ye, Qiguo Meng, Yuanxiu Wei, Xinyue Su

    Published 2024-02-01
    “…Before the inflection point, thiamine intake was not significantly associated with cognitive decline. Beyond the inflection point, each unit increase in thiamine intake (mg/day) was associated with a significant decrease of 4.24 (95% CI: 2.22 to 6.27) points in the global score and 0.49 (95% CI: 0.23 to 0.76) standard units in the composite score within 5 years. …”
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  16. 4536

    Real-world evaluation of physiotherapist-led exercise prehabilitation and rehabilitation during autologous stem cell transplantation in myeloma: a single-centre experience by Orla McCourt, Joanne Land, Neil Rabin, Kwee Yong, Abi Fisher, Jonathan Sive, Charalampia Kyriakou, Michael K Luong, Alasdair Longden

    Published 2025-01-01
    “…Changes in 6 min walk test and timed sit-to-stand were significant and beyond thresholds of clinical importance. Improvements were also seen in the domains of QoL.Conclusions Implementation of physiotherapist-led assessments in the myeloma clinic and group exercise delivery under remote supervision are acceptable to patients undergoing ASCT and indicate benefit in improving function and QoL.…”
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  17. 4537

    The accumulation of harmful genes within the ROH hotspot regions of the Tibetan sheep genome does not lead to genetic load by Lixia Sun, Chao Yuan, Tingting Guo, Yaqin Bai, Zengkui Lu, Jianbin Liu

    Published 2025-01-01
    “…Current research on ROH predominantly focuses on inbreeding and the signals of selection; however, there is a paucity of investigation into the genetic load and selective pressures associated with ROH, both within these regions and beyond. On one hand, genes located situated ROH hotspot regions exhibit a degree of conservation in their genomic segments; on the other hand, these regions may also serve as critical loci for identifying signals of selection. …”
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  18. 4538
  19. 4539

    The Relationship of Tumor-infiltrating Lymphocyte Ratio with Histopathological Parameters and Effect on Survival in Colorectal Cancers by İsra Serda Oğuz, Sinan Koca, Seval Ay Ersoy, Özgecan Dülgar, Ayşenur Toksöz, Mahmut Gümüş

    Published 2024-12-01
    “…The TIL ratio was identified as a prognostic factor beyond the effects of stage, grade, lymphovascular invasion, CEA level, and MSI status. …”
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  20. 4540

    HDL proteome and apolipoproteins concentrations in severe ICU COVID-19 patients by Floran Begue, Bryan Veeren, Philippe Rondeau, Aline-Marie Florence, Simon Jamard, Philippe Montravers, Sébastien Tanaka, Olivier Meilhac, on behalf of French COVID Study Group

    Published 2025-01-01
    “…Despite the crucial role that these nanoparticles play in SARS-CoV-2 infection, few studies have examined their structure during COVID-19 beyond HDL quantity. The study aimed to assess apolipoprotein levels in COVID-19 patients who either survived or died following ICU admission. …”
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