A conceptual framework for the instructional design of a Moodle-based e-learning course for mainstreaming informal master’s education outcomes into ESP teaching in a formal non-lin... by Larisa M. Galchuk

“…The research highlights the transformation of students’ informal cognitive activities from incidental and accidental learning to conscious and purposeful self-directed learning as a precondition for the successful implementation of a course on integrative mastering of an academic discipline in a formal context and beyond. This involves further development of the master’s systemic competencies and their deliberate transfer from formal to informal educational contexts while working with the learning resources of the lecture and project clusters within the thematic units of the online course. …”
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Improving the Biostability of Extra Virgin Olive Oil with Olive Fruit Extract During Prolonged Deep Frying by Taha Mehany, José M. González-Sáiz, Consuelo Pizarro

“…Moreover, sensory analysis revealed that positive attributes in EVOOs—such as fruity, bitter, and pungent notes—decreased significantly with increasing temperature and frying duration (<i>p</i> < 0.05). Beyond 210 °C/6 h, these attributes were rated at zero. …”
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Association between nutritional inflammation index and diabetic foot ulcers: a population-based study by Zhou Lin, Wanli Zhuang, Lei Wang, Weifeng Lan

“…Left of the inflection point, the relationship was negatively correlated. Beyond this point, further increased in ANLR no longer decrease DFU risk.ConclusionThe study not only proposed a new comprehensive indicator for predicting DFU for the first time but also specified the impact of ANLR on DFU risk. …”
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Exploring coastal climate adaptation through storylines: Insights from cyclone Idai in Beira, Mozambique by Henrique M.D. Goulart, Panagiotis Athanasiou, Kees van Ginkel, Karin van der Wiel, Gundula Winter, Izidine Pinto, Bart van den Hurk

“…Combining both conditions increases impacts beyond 37 times. An adaptation strategy combining flood protection and accommodation measures reduces impacts by maximum 83%, while a seawall strategy reduces these by 10%. …”
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Therapeutic potential of brentuximab vedotin in breast cancer and lymphoma via targeted apoptosis and gene regulation by Abeer Ezzat, Mohga Shafiek, Shimaa Shawki, Shaimaa Abdel-Ghany, Mahmoud Nazih, Hussein Sabit

“…Additionally, the study investigated the potential of repurposing this drug for new therapeutic reasons, beyond its original indications. The study evaluates the cytotoxic effects of Brentuximab vedotin across five cell lines: normal human skin fibroblasts (HSF), three breast cancer cell lines (MCF-7, MDA-MB-231, and T-47D), and histiocytic lymphoma (U-937). …”
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Assessment of the Impact of Floods to the Local Community in Nyarusiza Sub-County Kisoro District. by Murengezi, Innocent

“…When this tired or collected water reaches beyond the storage capacity limit, it ends up in flood. …”
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Assessing the Effect of Large Class Size and Pupils Academic Performance in Public Primary School in Rukungiri Municipality. by Kashumbusha, Robert

“…These included quality teaching and assessment suffering in large, lack of funding was perceived to impinge well beyond the classroom to the workplace and ultimately to the state of the economy, lack of appropriate value associated with teaching, school administration creating an environment that affects academic standards either positively or negatively. …”
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The Effect of Delegation of Responsibilities on Teachers’ Performance in Selected Secondary Schools in Kabale Municipality, Kabale District. by Seth, Ahumuza

“…They also develop the willingness to work beyond normal time, putting in more effort and have better attitudes towards their jobs. …”
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Severe primary graft failure: Are there lasting impacts? Analysis from the PHTS Database by Jennifer Conway, MD, Tara Pidborochynski, MSc, James K. Kirklin, MD, Ryan Cantor, PhD, Hong Zhao, PhD, Aryaz Sheybani, MD, Jacqueline Lamour, MD, Lakshmi Gokanapudy Hahn, MD, Leslie Collins, MD, Jessica Laks, MD, Darren H. Freed, MD, PhD

“…PGF was an independent predictor of overall graft loss (hazard ratios [HR] 4.7, p < 0.0001) and conditional survival to 30 days (HR 2.47, p < 0.0001) and 90 days (HR 1.6, p = 0.012) but not beyond 1 year. Conclusions: Severe PGF is an independent predictor of early mortality post-HTx but subsequently does not further impact long-term survival, overall risk of rejection, or CAV. …”
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Support Needs of Patients with Cushing’s Disease and Cushing’s Syndrome: Results of a Survey Conducted in Germany and the USA by Ilonka Kreitschmann-Andermahr, Sonja Siegel, Christa Gammel, Karen Campbell, Leslie Edwin, Agnieszka Grzywotz, Victoria Kuhna, Maria Koltowska-Häggström, Oliver Müller, Michael Buchfelder, Bernadette Kleist

“…In view of the high disease burden of CD/CS patients and long-term impaired quality of life, the present survey was conducted to gain information about subjective illness distress and patients’ specific needs in terms of supportive measures beyond medical interventions. Patients and Methods. …”
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Understanding social behaviours across neurodiverse young people: roles of social cognition and self-regulation by Iciar Iturmendi-Sabater, Evdokia Anagnostou, Marc A. Fournier, Jennifer Crosbie, Russell Schachar, Robert Nicolson, Stelios Georgiadis, Elizabeth Kelley, Jessica Jones, Jessica Brian, Hsiang-Yuan Lin, Meng-Chuan Lai

“…Conclusions Self-regulation, beyond social cognition, substantially explains social behaviours across neurodiverse young people. …”
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J-shaped association between dietary thiamine intake and the risk of cognitive decline in cognitively healthy, older Chinese individuals by Yuanyuan Zhang, Xianhui Qin, Chengzhang Liu, Chun Zhou, Mengyi Liu, Panpan He, Ziliang Ye, Qiguo Meng, Yuanxiu Wei, Xinyue Su

“…Before the inflection point, thiamine intake was not significantly associated with cognitive decline. Beyond the inflection point, each unit increase in thiamine intake (mg/day) was associated with a significant decrease of 4.24 (95% CI: 2.22 to 6.27) points in the global score and 0.49 (95% CI: 0.23 to 0.76) standard units in the composite score within 5 years. …”
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Real-world evaluation of physiotherapist-led exercise prehabilitation and rehabilitation during autologous stem cell transplantation in myeloma: a single-centre experience by Orla McCourt, Joanne Land, Neil Rabin, Kwee Yong, Abi Fisher, Jonathan Sive, Charalampia Kyriakou, Michael K Luong, Alasdair Longden

“…Changes in 6 min walk test and timed sit-to-stand were significant and beyond thresholds of clinical importance. Improvements were also seen in the domains of QoL.Conclusions Implementation of physiotherapist-led assessments in the myeloma clinic and group exercise delivery under remote supervision are acceptable to patients undergoing ASCT and indicate benefit in improving function and QoL.…”
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The accumulation of harmful genes within the ROH hotspot regions of the Tibetan sheep genome does not lead to genetic load by Lixia Sun, Chao Yuan, Tingting Guo, Yaqin Bai, Zengkui Lu, Jianbin Liu

“…Current research on ROH predominantly focuses on inbreeding and the signals of selection; however, there is a paucity of investigation into the genetic load and selective pressures associated with ROH, both within these regions and beyond. On one hand, genes located situated ROH hotspot regions exhibit a degree of conservation in their genomic segments; on the other hand, these regions may also serve as critical loci for identifying signals of selection. …”
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The Interactive Effects of Fruit Intake Frequency and Serum miR-484 Levels as Biomarkers for Incident Type 2 Diabetes in a Prospective Cohort of the Spanish Adult Population: The D... by Ana Lago-Sampedro, Wasima Oualla-Bachiri, Cristina Maldonado-Araque, Sergio Valdés, Inmaculada González-Molero, Viyey Doulatram-Gamgaram, Elias Delgado, Felipe J. Chaves, Luis Castaño, Alfonso Calle-Pascual, Josep Franch-Nadal, Gemma Rojo-Martínez, Sara García-Serrano, Eva García-Escobar

“…This study also suggests that the combined effect of low miR-484 levels and occasional fruit intake may increase the risk of T2DM beyond their independent effects.…”
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HDL proteome and apolipoproteins concentrations in severe ICU COVID-19 patients by Floran Begue, Bryan Veeren, Philippe Rondeau, Aline-Marie Florence, Simon Jamard, Philippe Montravers, Sébastien Tanaka, Olivier Meilhac, on behalf of French COVID Study Group

“…Despite the crucial role that these nanoparticles play in SARS-CoV-2 infection, few studies have examined their structure during COVID-19 beyond HDL quantity. The study aimed to assess apolipoprotein levels in COVID-19 patients who either survived or died following ICU admission. …”
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Reproductive modes in populations of late-acting self-incompatible and self-compatible polyploid Ludwigia grandiflora subsp. hexapetala in western Europe by Stoeckel, Solenn, Becheler, Ronan, Portillo-Lemus, Luis, Harang, Marilyne, Besnard, Anne-Laure, Lassalle, Gilles, Causse-Védrines, Romain, Michon-Coudouel, Sophie, Park, Daniel J., Pope, Bernard J., Petit, Eric J., Barloy, Dominique

“…The overall maintenance of higher genetic diversity with the possibility of maintaining populations clonally in the absence of compatible partners may explain why long-styled individuals seem to be more prevalent in all newly expanding populations worldwide. Beyond Lgh, our methodological approach may inspire future studies to assess the reproductive modes in other autopolyploid populations.…”
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Synaptotagmin-1 attenuates myocardial programmed necrosis and ischemia/reperfusion injury through the mitochondrial pathway by Teng Sun, Jialei Li, Shuang Wang, Yu Han, Xiangyu Tao, Min Yuan, Zhijie Jing, Ting Liu, Yuehong Qi, Siqi Liu, Yanlin Feng, Jiasong Chang, Lan Zhou, Lijuan Gao, Jianyun Shi, Ruihong Ning, Jimin Cao

“…The later findings of Syt1 expressions in many non-neuronal tissues including muscles suggest that Syt1 may exert important functions beyond regulation of neurotransmitter release. Syt1 is highly expressed in cardiomyocytes and has been used as an extracellular molecular probe for SPECT imaging of cardiac cell death in acute myocardial infarction. …”
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How drinking motives mediate associations between sexual orientation and indicators of alcohol use – a study among young Swiss men by Matthias Wicki, Matthias Wicki, Simon Marmet, Joseph Studer, Joseph Studer, Kim Bloomfield, Kim Bloomfield, Kim Bloomfield, Gerhard Gmel, Gerhard Gmel, Gerhard Gmel, Gerhard Gmel

“…No significant results or discernible patterns emerged for bisexual or mostly-homosexual men.DiscussionThese findings highlight the importance of considering the full spectrum of sexual orientations in healthcare and of broadening the focus on drinking motives beyond coping. Understanding the varied motives for alcohol use across the spectrum of sexual orientations facilitates tailored prevention strategies.…”
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Targeting enolase 1 reverses bortezomib resistance in multiple myeloma through YWHAZ/Parkin axis by Xuejie Gao, Qilin Feng, Qikai Zhang, Yifei Zhang, Chaolu Hu, Li Zhang, Hui Zhang, Guanli Wang, Ke Hu, Mengmeng Ma, Zhuning Wang, Yujie Liu, Dong An, Hongfei Yi, Yu Peng, Xiaosong Wu, Gege Chen, Xinyan Jia, Haiyan Cai, Jumei Shi

“…Abstract Background Enolase 1 (ENO1) is a conserved glycolytic enzyme that regulates glycolysis metabolism. However, its role beyond glycolysis in the pathophysiology of multiple myeloma (MM) remains largely elusive. …”
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