Chronic obstructive pulmonary disease and the risk of stroke: a systematic review protocol by Jennifer K Quint, Ann D Morgan, Chetna Sharma, Kieran J Rothnie

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Protocol for a systematic review of economic evaluations considering costs and health outcomes of weather and climate-related extreme events in humans by Collins Iwuji, Saeideh Babashahi, Kingsley Orievulu, Ekeminiabasi Eyita-Okon, Dominic Kniveton

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Phantom motor execution as a treatment for phantom limb pain: protocol of an international, double-blind, randomised controlled clinical trial by Brian E McGuire, Lina Bunketorp-Käll, Eva Lendaro, Liselotte Hermansson, Helena Burger, Corry K Van der Sluis, Monika Pilch, Katarzyna Kulbacka-Ortiz, Ingrid Rignér, Anita Stockselius, Lena Gudmundson, Cathrine Widehammar, Wendy Hill, Sybille Geers, Max Ortiz-Catalan

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Study protocol of a pilot randomised controlled trial assessing the feasibility and acceptability of RecoverEsupport: a digital health intervention to enhance recovery in women und... by Christopher Oldmeadow, Mitch J Duncan, Penny Reeves, Priscilla Viana da Silva, Rebecca Wyse, Helen Moore, Alison Zucca, Sancha Robinson, Stephen Ridley Smith, Emma Sansalone, Owen Morris, Rebecca Chenery, Lara Riley, Anna Palazzi-Parsons

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Defining polypharmacy in the elderly: a systematic review protocol by Seyede Salehe Mortazavi, Mohsen Shati, Seyed Kazem Malakouti, Abasali Keshtkar, Mohsen Bazargan, Shervin Assari

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Older, vulnerable patient view: a pilot and feasibility study of the patient measure of safety (PMOS) with patients in Australia by Jeffrey Braithwaite, Natalie Taylor, Rebecca Lawton, Robyn Clay-Williams, Emily Hogden, Zhicheng Li

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Total glucosides of paeony for rheumatoid arthritis: a protocol for a systematic review by Jing Luo, Guo-Yan Yang, Di-Er Jin, Ying-Ze Zhang, Jian-Ming Wang, Wei-Ping Kong, Qing-Wen Tao

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Development and validation of the Multimorbidity Treatment Burden Questionnaire (MTBQ) by Daisy Gaunt, Chris Salisbury, Mei-See Man, Katherine Chaplin, Polly Duncan, Mairead Murphy

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Barriers and enablers to implementing clinical practice guidelines in primary care: an overview of systematic reviews by Tao Wang, Xian-Liang Liu, Jing-Yu (Benjamin) Tan, Isabella Zhao

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Efficacy of phototherapy to treat facial ageing when using a red versus an amber LED: a protocol for a randomised controlled trial by Lidiane Rocha Mota, Christiane Pavani, Lara Jansiski Motta, Anna Carolina Ratto Tempestini Horliana, Ivone da Silva Duarte, Daniela de Fátima Teixeira da Silva

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European Working Time Directive and doctors’ health: a systematic review of the available epidemiological evidence by Consol Serra, Evangelia Demou, Ewan B Macdonald, Sergio Vargas-Prada, Maria Cruz Rodriguez-Jareño, Kaveh A Sanati, Alenka Škerjanc, Pedro G Reis, Ritva Helimäki-Aro

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Emergency Medicine Palliative Care Access (EMPallA): protocol for a multicentre randomised controlled trial comparing the effectiveness of specialty outpatient versus nurse-led tel... by Jeanne Cho, Michael Hill, Corita R Grudzen, Deborah J Shim, Abigail M Schmucker, Keith S Goldfeld, Lauren Southerland, Jeffrey M Caterino, Marie-Carmelle Elie, Robert Swor, Susan E Cohen, Arum Kim, Joseph Lowy, Jennifer S Scherer, Nancy E Bael, Ellin Gafford, Joshua Lakin, Paige Barker, Angela Chmielewski, Jennifer Kapo, Audrey Tan, Rebecca Yamarik, Susan Salz, Stephen Ryan, Anne Kim, Isabel Castro, Amelia Hargrove, Laura Stuecher, Nora Daut, Juanita Booker-Vaughns, Garrett K Chan, J Nicholas Dionne-odom, Patrick Dunn, Robert Galvin, Ernest A Hopkins III, Margaret M Maguire, Neha Reddy Pidatala, Dawn Rosini, Sally Welsh, Karen Jubanyik, Ada L Rubin, Kei Ouchi, Rebecca Murray, Nicole Tang, Marie Bakitas, Abraham Brody, Caroline Blaum, Mara Flannery, Richard Tamirian, Pamela Marsack, Jennifer Bonito, Romilla Batra, Donna C Sadasivan, Eric David Isaacs, Constance L Kizzie-Gillett, William K Vaughan, Pluscedia G Williams, Angela Young-Brinn

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Energy management education for persons living with long COVID-related fatigue (EMERGE): protocol of a two-parallel arms target trial emulation study in a multicentre outpatient in... by Emilia Riggi, Marco Barbero, Gian Luca Di Tanna, Ruth Hersche, Andrea Weise

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Protocol for a randomised phase 3 trial evaluating the role of Finasteride in Active Surveillance for men with low and intermediate-risk prostate cancer: the FINESSE Study by Samuel Smith, Peter Sasieni, William Cross, Richard Bryant, Steven Kennish, James Catto, Rachel Hubbard, Simon Faulkner, Rohit Chahal, Mohantha Dooldeniya, Marcus Cumberbatch, Bernard North, Alastair D Lamb, Roseann Kealy, Selina Bhattrai

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Protocol of an open-label safety and feasibility pilot study of ketamine-assisted psychotherapy for methamphetamine use disorder (the KAPPA trial) by Jonathan Brett, Celia Morgan, Nadine Ezard, Brendan Clifford, Krista J Siefried, Robert May, Liam Acheson, Kathryn Fletcher, Harriet MacDonald, Gillinder Bedi, Alexandre Guerin, Elizabeth Knock, Michael Millard, Jess Doumany

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Systematic comparison of Mendelian randomisation studies and randomised controlled trials using electronic databases by Jie Zheng, George Davey Smith, Tom R Gaunt, Maria K Sobczyk

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Beneficial and harmful effects of duloxetine versus placebo, ‘active placebo’ or no intervention for adults with major depressive disorder: a systematic review with meta-analysis a... by Christian Gluud, Marija Barbateskovic, Joanna Moncrieff, Faiza Siddiqui, Janus C Jakobsen, Mathias Maagaard, Sophie Juul, Johanne Juul Petersen, Caroline Barkholt Kamp, Mark Abie Horowitz, Kiran Kumar Katakam

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BIOSKIN: A Protocol for the Copenhagen Translational Skin Immunology Biobank and Research Programme by Lone Skov, Jeanne Duus Johansen, Marianne Bengtson Løvendorf

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Understanding the causes of intravenous medication administration errors in hospitals: a qualitative critical incident study by Darren M Ashcroft, Richard N Keers, Jonathan Cooke, Steven D Williams

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Role of private providers in the implementation of the national health insurance scheme in Zambia: a qualitative study of perceptions and experiences by Jesper Sundewall, Warren Mukelabai Simangolwa

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