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Immunological Links to Nonspecific Effects of DTwP and BCG Vaccines on Infant Mortality
Published 2011-01-01“…In contrast, similar studies suggest that many African females and males may have their lives saved each year by the nonspecific immunological benefits of Bacillus Calmette-Guerin (BCG) vaccination. From an immunological point of view, we hypothesise that the adverse effects of DTwP vaccine may occur because of the Th2-polarising effect of the aluminium phosphate adjuvant in the vaccine and because intramuscular administration of the vaccine may cause chronic inflammation at the site of injection. …”
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The Impact of Transcriptomics on the Fight against Tuberculosis: Focus on Biomarkers, BCG Vaccination, and Immunotherapy
Published 2011-01-01“…This paper analyzes how transcriptomics are supporting the translation of basic research into therapies by resolving three key issues in the fight against TB: (a) the discovery of biomarkers, (b) the explanation of the variability of protection conferred by BCG vaccination, and (c) the development of new immunotherapeutic strategies to treat TB.…”
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Neonatal BCG vaccination and child survival in TB-exposed and TB-unexposed children: a prospective cohort study
Published 2020-02-01“…Interventions to increase timely BCG vaccination are urgently warranted.…”
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Comparative performance of tuberculin and defined-antigen cocktails for detecting bovine tuberculosis in BCG-vaccinated cattle in natural settings
Published 2025-02-01Subjects: “…BCG vaccination…”
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Therapeutic Effects of BCG Vaccination on Type 1 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Published 2020-01-01“…The Bacillus Calmette–Guerin (BCG) vaccine can modulate the immune response and decelerate disease progression. …”
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Infantile BCG osteomyelitis ultimately diagnosed as a result of trauma
Published 2025-03-01Subjects: Get full text
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Interferon (IFN)-gamma (γ) inducible protein 10 (IP-10) in the diagnosis of latent and active tuberculosis in Bacille Calmette Guerin (BCG)-vaccinated pediatric population.
Published 2025-01-01“…<h4>Conclusions</h4>IP-10 might be a viable alternative biomarker to IFN-γ for identifying M.tb infection in BCG-vaccinated children, although it cannot distinguish between latent and active TB cases. …”
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Effect of Bacille Calmette–Guérin vaccination on immune responses to SARS‐CoV‐2 and COVID‐19 vaccination
Published 2025-01-01Subjects: “…Bacille Calmette–Guérin (BCG) vaccine…”
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Immunogenicity and protective efficacy of a multi-antigenic adenovirus-based vaccine candidate against Mycobacterium tuberculosis
Published 2025-01-01Subjects: Get full text
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Mycobacterium spp. exposure, childhood vaccinations, and early childhood brain and CNS cancers
Published 2025-01-01Subjects: Get full text
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Hubungan antara Pembentukan Scar Vaksin BCG dan Kejadian Infeksi Tuberkulosis
Published 2016-08-01“…One of the way to prevent tuberculosis is immunization of BCG vaccine which given since infant. The Scar of BCG vaccine can formed after injection or not. …”
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Perbedaan Kadar Interferon Gamma dan Interleukin-10 pada Orang Dewasa Terinfeksi Ascaris Lumbricoides dengan Tidak Terinfeksi yang Diinduksi Vaksin Bacille Calmette-Guerin
Published 2015-09-01“…It can be concluded that Ascaris lumbricoides infection can pressure IFN-y production on given BCG vaccine. </p><p>Keywords: ascaris lumbricoides, BCG vaccine, interferon gamma (IFN-γ), Interleukin 10 (IL-10)<br /><br /><br /><br /></p>…”
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Perbedaan Kadar Interferon Gamma dan Interleukin-10 pada Orang Dewasa Terinfeksi Ascaris Lumbricoides dengan Tidak Terinfeksi yang Diinduksi Vaksin Bacille Calmette-Guerin
Published 2016-01-01“…It can be concluded that infect Ascaris lumbricoides can pressure IFN-y production on given BCG vaccine. </em></p><p><strong><em>Keywords:</em></strong><em> Ascaris lumbricoides, BCG vaccine, Interfereon gamma (IFN-γ), Interleukin 10 (IL-10)</em></p>…”
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Applied Comparison of Meta-analysis Techniques
Published 2013-02-01“…**Methods:** Three different meta-analysis techniques were applied to a dataset looking at the effects of the bacille Calmette-Guerin (BCG) vaccine on tuberculosis (TB). First, a fixed-effects model was applied; then a random-effects model; and third meta-regression with study-level covariates were added to the model. …”
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Investigation of Functional Activity of Cells in Granulomatous Inflammatory Lesions from Mice with Latent Tuberculous Infection in the New Ex Vivo Model
Published 2013-01-01“…Monolayer cultures of cells that migrated from individual granulomas were established in the proposed culture settings for mouse spleen and lung granulomas induced by in vivo exposure to BCG vaccine. The cellular composition of individual granulomas was analyzed. …”
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An HPLC-based Assay to Study the Activity of Cyclic Diadenosine Monophosphate (C-di-AMP) Synthase DisA from Mycobacterium smegmatis
Published 2024-12-01“…Additionally, c-di-AMP demonstrates potent adjuvant properties, particularly when administered alongside the Bacillus Calmette–Guérin (BCG) vaccine through mucosal routes. Because of its pivotal role in bacterial signaling and host immune response, this molecule has garnered significant interest from the pharmaceutical industry. …”
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Successful Handling of Disseminated BCG Disease in a Child with Severe Combined Immunodeficiency
Published 2011-01-01“…In high-burden countries, Mycobacterium bovis Bacillus Calmette-Guérin (BCG) vaccine is administered in newborn to prevent severe Mycobacterium tuberculosis infection. …”
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Predictive Biomarkers of Bacillus Calmette-Guérin Immunotherapy Response in Bladder Cancer: Where Are We Now?
Published 2012-01-01“…The most effective therapeutic option for managing nonmuscle invasive bladder cancer (NMIBC), over the last 30 years, consists of intravesical instillations with the attenuated strain Bacillus Calmette-Guérin (the BCG vaccine). This has been performed as an adjuvant therapeutic to transurethral resection of bladder tumour (TURBT) and mostly directed towards patients with high-grade tumours, T1 tumours, and in situ carcinomas. …”
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