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    Elevated levels of neutrophils with a pro-inflammatory profile in Turner syndrome across karyotypes by Jesper Just, Lukas Ochsner Reynaud Ridder, Emma Bruun Johannsen, Jens Magnus Bernth Jensen, Mikkel Steen Petersen, Helene Viborg Christensen, Kenneth Kjærgaard, Jacob Redder, Simon Chang, Kirstine Stochholm, Anne Skakkebæk, Claus Højbjerg Gravholt

    Published 2025-02-01
    “…Abstract Turner syndrome (TS) presents with multiple karyotypes, including 45,X monosomy and variants such as isochromosomes and mosaicism, and is characterized by several co-morbidities, including metabolic conditions and autoimmunity. Here, we investigated the genomic landscapes across a range of karyotypes. …”
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    Roitt's essential immunology / by Delves, Peter J., Martin, Seamus J., 1966-, Burton, Dennis R., Roitt, Ivan M. (Ivan Maurice)

    Published 2017
    Table of Contents: “…Innate immunity -- Specific acquired immunity -- Antibodies -- Membrane receptors for antigen -- Antigen-specific recognition -- Immunological methods and applications [JS2] -- The anatomy of the immune response -- Lymphocyte activation -- The production of effectors -- The regulation of the immune response -- Development and evolution of the immune response -- Adversarial strategies during infection -- Vaccines -- Immunodeficiency -- Allergy and other hypersensitivities -- Transplantation -- Tumor immunology -- Autoimmune diseases.…”
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  18. 58

    Application of deep learning models on single-cell RNA sequencing analysis uncovers novel markers of double negative T cells by Tian Xu, Qin Xu, Ran Lu, David N. Oakland, Song Li, Liwu Li, Christopher M. Reilly, Xin M. Luo

    Published 2024-12-01
    “…They have increasingly gained recognition for their novel roles in the immune system, especially under autoimmune conditions. Conventional machine learning approaches such as principal component analysis have been employed in single-cell RNA sequencing (scRNA-seq) analysis to characterize DNT cells. …”
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    Targeted detection of endogenous LINE-1 proteins and ORF2p interactions by Mathias I. Nielsen, Justina C. Wolters, Omar G. Rosas Bringas, Hua Jiang, Luciano H. Di Stefano, Mehrnoosh Oghbaie, Samira Hozeifi, Mats J. Nitert, Alienke van Pijkeren, Marieke Smit, Lars ter Morsche, Apostolos Mourtzinos, Vikram Deshpande, Martin S. Taylor, Brian T. Chait, John LaCava

    Published 2025-02-01
    “…Abstract Background Both the expression and activities of LINE-1 (L1) retrotransposons are known to occur in numerous cell-types and are implicated in pathobiological contexts such as aging-related inflammation, autoimmunity, and in cancers. L1s encode two proteins that are translated from bicistronic transcripts. …”
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