Helicobacter  pylori Eradication Therapies in the Era of Increasing Antibiotic Resistance: A Paradigm Shift to Improved Efficacy by Sotirios D. Georgopoulos, Vasilios Papastergiou, Stylianos Karatapanis

“…With the rising prevalence of antimicrobial resistance, the eradication rates of Helicobacter pylori (H. pylori) with standard treatments are decreasing to unacceptable levels (i.e., ≤80%) in most countries. …”
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Summary of Canadian Guidelines for the Initial Management of Community-Acquired Pneumonia: An Evidence-Based Update by the Canadian Infectious Diseases Society and the Canadian Tho... by Lionel A Mandell, Thomas J Marrie, Ronald F Grossman, Anthony W Chow, Robert H Hyland, the Canadian CAP Working Group

“…Over the past several years, there have been significant advances in our knowledge and understanding of the etiology of the disease, and an appreciation of problems such as mixed infections and increasing antimicrobial resistance. The development of additional fluoroquinolone agents with enhanced activity against Streptococcus pneumoniae has been important as well. …”
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Lipopeptide adjuvants for antibiotics and vaccines: the future step in the fight against multidrug-resistant and extensively drug-resistant pathogens by Chloé O. Sebilleau, Steven J. Sucheck

“…Antibiotic adjuvants can allow for gram-positive bacteria (GPB) specific treatments to be used against gram-negative bacteria (GNB) infections, with minimal antimicrobial resistance (AMR). In the case of vaccines, they allow for modulation and increase of the immune response. …”
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Interaction between bacterial adhesins leads to coaggregation by the oral bacteria Veillonella parvula and Streptococcus gordonii by Jack C. Leo

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Canadian Guidelines for the Management of Acute Exacerbations of Chronic Bronchitis by Meyer S Balter, Jacques La Forge, Donald E Low, Lionel Mandell, Ronald F Grossman, the Chronic Bronchitis Working Group

“…The importance of emerging antimicrobial resistance to current antibiotics is reviewed and strategies to prevent future AECB episodes are suggested.…”
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Shared mechanisms of enhanced plasmid maintenance and antibiotic tolerance mediated by the VapBC toxin:antitoxin system by Sarah Hollingshead, Gareth McVicker, Maria R. Nielsen, YuGeng Zhang, Giulia Pilla, Rebekah A. Jones, Jonathan C. Thomas, Sarah E. H. Johansen, Rachel M. Exley, Ditlev E. Brodersen, Christoph M. Tang

“…Our findings highlight the links between plasmid maintenance and antibiotic tolerance, both of which can promote the development of antimicrobial resistance.IMPORTANCEOur work addresses two processes, the maintenance of plasmids and antibiotic tolerance; both contribute to the development of antimicrobial resistance in bacteria that cause human disease. …”
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Sharing of cmeRABC alleles between C. coli and C. jejuni associated with extensive drug resistance in Campylobacter isolates from infants and poultry in the Peruvian Amazon by Kerry K. Cooper, Evangelos Mourkas, Francesca Schiaffino, Craig T. Parker, Tackeshy N. Pinedo Vasquez, Paul F. Garcia Bardales, Pablo Peñataro Yori, Maribel Paredes Olortegui, Katia Manzanares Villanueva, Lucero Romaina Cachique, Hermann Silva Delgado, Matthew D. Hitchings, Steven Huynh, Samuel K. Sheppard, Ben Pascoe, Margaret N. Kosek

“…ABSTRACT Campylobacter is a serious health threat because of the rapid progressive evolution of antimicrobial resistance and efficient transmission from zoonotic as well as human sources. …”
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PGC-1α activation to enhance macrophage immune function in mycobacterial infections. by Joel R Frandsen, Zhihong Yuan, Brahmchetna Bedi, Zohra Prasla, Seoung-Ryoung Choi, Prabagaran Narayanasamy, Ruxana T Sadikot

“…Their incidence and prevalence are rising worldwide, due in part to elevated antimicrobial resistance which complicates treatment and potential successful outcomes. …”
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Prevalence and Antibiotic Resistance Pattern of Salmonella Isolated from Caecal Contents of Exotic Chicken in Debre Zeit and Modjo, Ethiopia by Destaw Asfaw Ali, Belege Tadesse, Aragaw Ebabu

“…The study demonstrated considerable prevalence and high antimicrobial resistant Salmonella in exotic chicken and indicates the potential importance of chickens as source of foodborne salmonellosis and multiple antimicrobial resistance of Salmonella. …”
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Analysis of Klebsiella Pneumonia and Resistance Genes Coding and Carbapenemase Production in National Referral Hospital Wastewater by Glory Gelarich Simanjuntak, Anis Karuniawati, Yulia Rosa Saharman, Windi Muziasari

“…This study aimed to determine Klebsiella pneumonia and resistance genes encoding ESBL and carbapenemase in hospital wastewater to obtain primary Antimicrobial Resistance (AMR) data in the environment, which was first conducted in Indonesia. …”
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Ode to Oseltamivir and Amantadine? by JM Conly, BL Johnston

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Plant-Derived Iron Nanoparticles for Removal of Heavy Metals by Deepika Thilakan, Jaie Patankar, Srushti Khadtare, Nilesh S. Wagh, Jaya Lakkakula, Khalid Mohamed El-Hady, Saiful Islam, Md. Rabiul Islam, Mohd Shahnawaz Khan, Nouf Omar Alafaleq, Mohammad Tarique

“…Irradiated nanoparticles have also exhibited antimicrobial resistance and adsorption. It is also observed that nanoparticles show a higher rate of efficacy at a lower pH. …”
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A systematised review and evidence synthesis on the broader societal impact of vaccines against Salmonella by Ezgi Dilek Demirtas, Rosanna Barnard, Jungseok Lee, Mark Jit

“…There were no studies measuring economic impact of antimicrobial resistance, changes in household behaviour or health inequalities.…”
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Central Venous Catheter-Associated Bloodstream Infections in Hemodialysis Patients: Another Patient Safety Bundle? by B Lynn Johnston, John M Conly

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A SYSTEMATIC REVIEW OF THE USE OF TULATHROMYCIN IN VETERINARY MEDICINE by Carmen (Pop) Moldovan, Alexandra Dreancă, Oana Rotar, Mihai Madru, Ioan Marcus

“…Data regarding antimicrobial resistance to tulathromycin is discrepant due to several sources that display negative results regarding the sole use of this macrolide and its off-label use. …”
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Role of SarA in Staphylococcus aureus: A Virulence Target For Therapeutic Strategies by Yi He Kuai, Jodi Woan-Fei Law, Yong Sze Ong, Vengadesh Letchumanan, Learn-Han Lee, Loh Teng-Hern Tan

“…In this review, we present an overview of the current understanding of the molecular mechanisms underlying the regulation of sarA gene expression, with a particular emphasis on its relevance in the development and sustenance of antimicrobial resistance, along with in the processes of biofilm formation and activation of virulence genes in MRSA. …”
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Antibiotic Resistance Profiling of Staphylococcus aureus Isolated from Clinical Specimens in a Tertiary Hospital from 2010 to 2012 by Alain C. Juayang, Gemma B. de los Reyes, April Joy G. de la Rama, Christine T. Gallega

“…Specifically, this study aimed to evaluate the antimicrobial resistance of S. aureus isolated from clinical specimens and to put emphasis on the prevalence of MRSA and Inducible Clindamycin Resistance. …”
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Rapid Identification of Drug-Resistant Tuberculosis Genes Using Direct PCR Amplification and Oxford Nanopore Technology Sequencing by Kaishun Zhao, Chunlin Tu, Wei Chen, Haiying Liang, Wenjing Zhang, Yilei Wang, Ye Jin, Jianrong Hu, Yameng Sun, Jun Xu, Yanfang Yu

“…Mycobacterium tuberculosis antimicrobial resistance has been continually reported and is a major public health issue worldwide. …”
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Predicting appropriateness of antibiotic treatment among ICU patients with hospital-acquired infection by Ella Goldschmidt, Ella Rannon, Daniel Bernstein, Asaf Wasserman, Michael Roimi, Anat Shrot, Dan Coster, Ron Shamir

“…Abstract Antimicrobial resistance is a rising global health threat, leading to ineffective treatments, increased mortality and rising healthcare costs. …”
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A novel broad-spectrum bacteriophage cocktail against methicillin-resistant Staphylococcus aureus: Isolation, characterization, and therapeutic potential in a mastitis mouse model. by Maryam Banar, Haniyeh Kamyab, Narges Torkashvand, Taghi Zahraei Salehi, Zargham Sepehrizadeh, Ahmad Reza Shahverdi, Mohammad Reza Pourmand, Mohammad Hossein Yazdi

“…In silico analyses have confirmed the absence of antimicrobial resistance or virulence factor-encoding genes within their genomes. …”
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