The Role and Therapeutic Potential of Endothelial Progenitor Cells in Tumor Neovascularization by Branislava Janic, Ali S. Arbab

“…Numerous studies over the past decades demonstrated that neovascularization associated with tumor growth occurs via angiogenic and vasculogenic mechanisms that involve sprouting angiogenesis, intussusceptive angiogenesis, vessel co-option, vasculogenic mimicry, lymphangiogenesis, and the recruitment of endothelial progenitor cells (EPCs). …”
Get full text

Natural Killer Cells from Malignant Pleural Effusion Are Endowed with a Decidual-Like Proangiogenic Polarization by Annalisa Bosi, Silvia Zanellato, Barbara Bassani, Adriana Albini, Alessandra Musco, Maria Cattoni, Matteo Desio, Elisa Nardecchia, Davide Giuseppe D’Urso, Andrea Imperatori, Lorenzo Dominioni, Douglas M. Noonan, Lorenzo Mortara, Antonino Bruno

Get full text

MicroRNAs in Postischemic Vascular Repair by Andrea Caporali, Costanza Emanueli

“…The term angiogenesis describes the growth of endothelial sprouts from preexisting postcapillary venules. …”
Get full text

Diabetic Macular Edema Pathophysiology: Vasogenic versus Inflammatory by Pedro Romero-Aroca, Marc Baget-Bernaldiz, Alicia Pareja-Rios, Maribel Lopez-Galvez, Raul Navarro-Gil, Raquel Verges

“…This paper provides a review of the data currently available, focusing on VEGF, angiogenesis, and inflammation. Our analysis suggests that angiogenesis and inflammation act interdependently during the development of DME. …”
Get full text

An Evaluation of Cellulose Hydrogels Derived from <i>tequilana</i> Weber Bagasse for the Regeneration of Gingival Connective Tissue in Lagomorphs by Silvia López-Domínguez, Juan Carlos Cuevas-González, León Francisco Espinosa-Cristóbal, Judith Virginia Ríos-Arana, Rosa Alicia Saucedo Acuña, María Verónica Cuevas-González, Erasto Armando Zaragoza-Contreras, Karla Lizette Tovar Carrillo

“…Regarding angiogenesis, in the specimens where membranes were implanted, its presence predominated in all variants (50%), followed by diffuse angiogenesis (37.5%), and finally the absence of angiogenesis (12.5%).…”
Get full text

Gremlin, a Bone Morphogenetic Protein Antagonist, Is a Crucial Angiogenic Factor in Pituitary Adenoma by Kenta Koketsu, Daizo Yoshida, Kyongsong Kim, Yudo Ishii, Shigeyuki Tahara, Akira Teramoto, Akio Morita

“…Several recent reports have shown that Gremlin is also involved in angiogenesis of lung cancer and diabetic retinopathy. …”
Get full text

Communication between endothelial cells and osteoblasts in regulation of bone homeostasis: Notch players by Daria Perepletchikova, Anna Malashicheva

“…Understanding the interplay between angiogenesis and osteogenesis is currently a focus of research efforts in order to facilitate and improve osteogenesis when needed. …”
Get full text

Small Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Enhanced Proangiogenic Potential of Cardiac Fibroblasts via Angiopoietin-Like 4 by Jiejie Li, Xin Xu, Suyan Fei, Ren Wang, Hua Wang, Wei Zhu, Yuanyuan Zhao

“…The sEVs regulated CFs to promote angiogenesis via Angptl4 in an inflammatory environment. …”
Get full text

Vascular endothelial growth factor A: friend or foe in the pathogenesis of HIV and SARS-CoV-2 infections? by Mieke A. van der Mescht, Helen C. Steel, Ronald Anderson, Theresa M. Rossouw

“…The processes involved in vascular homeostasis and angiogenesis are reviewed briefly before exploring the interplay between hypoxia, VEGF-A, neuropilin-1 (NRP-1), and inflammatory pathways. …”
Get full text

Constructing Tissue-Engineered Dressing Membranes with Adipose-Derived Stem Cells and Acellular Dermal Matrix for Diabetic Wound Healing: A Comparative Study of Hypoxia- or Normoxi... by Wen Zhou, Xin Zhao, Xin Shi, Can Chen, Yanpeng Cao, Jun Liu

“…Diabetes foot ulcer (DFU) is a serious complication of diabetes, characterized by impaired vascular function, limited angiogenesis, and chronic inflammation. Direct stem cell injection on treating DFU is far from satisfactory in clinical practice, as this therapy neither protects nor localizes the injected cell suspension at the chronic ulcer site. …”
Get full text

The effect of Klotho protein complexed with nanomaterials on bone mesenchymal stem cell performance in the treatment of diabetic ischaemic ulcer by Rui Tang, Gang Zhao, Yuqiao Wang, Ruixue Zhang

“…Abstract A lack of angiogenesis is the key problem in the healing of diabetic foot ulcers. …”
Get full text

Dental Pulp Mesenchymal Stem Cells Attenuate Limb Ischemia via Promoting Capillary Proliferation and Collateral Development in a Preclinical Model by Youfeng Li, Yuning Zhang, Hua Wang, Chengfeng Sun, Dongmei Liu, Hongying Liu, Jia He, Furong Chen, Weiting Wang, Xi Jiang, Chu-tse Wu, Yuefeng Yang

“…We speculated that DP-MSCs might stimulate angiogenesis and promote tissue repair via expressing and secreting angiogenic factors, growth factors, and chemokines, especially HGF and HIF-1α. …”
Get full text

Remote Continuous Microinjury-Triggered Cytokines Facilitate Severe Diabetic Foot Ulcer Healing via the Ras/Raf/MEK/ERK Pathway by Huang X, Liu J, Wu X, Mo Y, Luo X, Yang Y, Yang C, Liang X, Liang R, Chen Y, Fan Z, Lu W, Chen Y, Hua Q

“…Bone transport consists of continuous microinjuries/microfracture and induces bone formation and angiogenesis. Tibial cortex transverse transport (TTT) was found to promote angiogenesis at the foot and the healing of diabetic foot ulcers (DFUs). …”
Get full text

Matrix Metalloproteinases: Inflammatory Regulators of Cell Behaviors in Vascular Formation and Remodeling by Qishan Chen, Min Jin, Feng Yang, Jianhua Zhu, Qingzhong Xiao, Li Zhang

“…Abnormal angiogenesis and vascular remodeling contribute to pathogenesis of a number of disorders such as tumor, arthritis, atherosclerosis, restenosis, hypertension, and neurodegeneration. …”
Get full text

Cathepsin K Deficiency Impaired Ischemia-Induced Neovascularization in Aged Mice by Xueling Yue, Haiying Jiang, Ying Xu, Manli Xia, Xian-Wu Cheng

“…Cysteine protease cathepsin K (CatK) has been implicated in the process of angiogenesis, but the exact roles of individual CatK in vessel formation during aging are poorly understood. …”
Get full text

The Role of Connexin in Ophthalmic Neovascularization and the Interaction between Connexin and Proangiogenic Factors by Chuyang Xu, Hong Zhang, Wei Zhong, Hongyan Zhou

“…Numerous studies have demonstrated that connexin in vascular endothelial cells plays an important role in angiogenesis and vascular leakage. The purpose of this study was to investigate the effect between the angiogenesis-associated factor and the connexin. …”
Get full text

Thrombospondin-1: Multiple Paths to Inflammation by Zenaida Lopez-Dee, Kenneth Pidcock, Linda S. Gutierrez

“…If the underlying event inducing inflammation is not addressed and homeostasis is not restored, this process can become chronic and lead to angiogenesis and carcinogenesis. Thrombospondin-1 (TSP-1) is a matricellular protein involved in angiogenesis, cancer, and inflammation. …”
Get full text

The Role of PPARs in the Endothelium: Implications for Cancer Therapy by David Bishop-Bailey, Karen E. Swales

“…This review will discuss the roles of PPARs in endothelial cells in relation to angiogenesis, inflammation, coagulation, and platelet control pathways. …”
Get full text

Galangin-Loaded Gold Nanoparticles: Molecular Mechanisms of Antiangiogenesis Properties in Breast Cancer by Malik H. Qaddoori, Hanady S. Al-Shmgani

“…Angiogenesis is important for tissue during normal physiological processes as well as in a number of diseases, including cancer. …”
Get full text

Programmed Cell Death of Endothelial Cells in Myocardial Infarction and Its Potential Therapeutic Strategy by Mingyue Wu, Zixia Huang, Lijin Zeng, Chunfei Wang, Deming Wang

“…Cardiovascular disease research has historically focused on promoting angiogenesis following myocardial damage. Myocardial vascular repair is crucial for improving myocardial infarction prognosis. …”
Get full text