Chitooligosaccharides promote diabetic wound healing by mediating fibroblast proliferation and migration by Zihan Li, Chuwei Zhang, Lei Wang, Qingrong Zhang, Yipeng Dong, Xinyu Sha, Bolin Wang, Zhihan Zhu, Wenmiao Wang, Yongjun Wang, Youlang Zhou, Yi Zhang

“…Additionally, COS increased collagen III deposition and angiogenesis at the wound sites. The COS also mitigated inflammatory responses by controlling leukocyte infiltration and bacterial infection. …”
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The Notch Pathway in Breast Cancer Progression by Emmanuel N. Kontomanolis, Sofia Kalagasidou, Stamatia Pouliliou, Xanthoula Anthoulaki, Nikolaos Georgiou, Valentinos Papamanolis, Zacharias N. Fasoulakis

“…The available literature in MEDLINE, PubMed, and Scopus, regarding the role of the Notch pathway in breast cancer progression was searched for related articles from about 1973 to 2017 including terms such as “Notch,” “Breast Cancer,” and “Angiogenesis.” Results. Notch signaling controls the differentiation of breast epithelial cells during normal development. …”
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Functional omics of ORP7 in primary endothelial cells by Juuso H. Taskinen, Minna Holopainen, Hanna Ruhanen, Miesje van der Stoel, Reijo Käkelä, Elina Ikonen, Salla Keskitalo, Markku Varjosalo, Vesa M. Olkkonen

“…Moreover, assays on angiogenesis, cholesterol efflux, and lipid droplet quantification were conducted. …”
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Systematic multiomics analysis and in vitro experiments suggest that ITGA5 could serve as a promising therapeutic target for ccRCC by Xiangxian Che, Xi Tian, Zhenda Wang, Shuxuan Zhu, Shiqi Ye, Yue Wang, Yihan Chen, Yiyun Huang, Aihetaimujiang Anwaier, Peifeng Yao, Yijia Chen, Keting Wu, Yifei Liu, Wenhao Xu, Hailiang Zhang, Dingwei Ye

“…Through overexpressing, silencing, and blocking ITGA5, we verified the role of ITGA5 in promoting ccRCC adverse biological activities; and the potential functions of ITGA5 in ccRCC were bioinformatically demonstrated, summarizing as cell proliferation, migration, and angiogenesis. The localization of ITGA5 primarily in endothelia and macrophages further verified its magnitude in angiogenesis and aroused our excavation in ITGA5 regulation of immune infiltration landscape. …”
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A new era considering inorganic trace elements and biological activity of dental biomaterials (angiogenic activity) by Mohammad Ali Saghiri, Armen Asatourian, Franklin Garcia-Godoy, Nader Sheibani

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Editorial for the Special Issue “Angiogenic Growth Factors in Tumor Development: Beyond New Blood Vessels Formation” by Camilla Palumbo, Loredana Albonici

“…A myriad of growth factors and receptors, whose effects are intertwined in complex interactions, do not only orchestrate tumor angiogenesis [...]…”
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Inhibition of microRNA-660-5p decreases breast cancer progression through direct targeting of TMEM41B by Valeria Villarreal-García, José Roberto Estupiñan-Jiménez, Vianey Gonzalez-Villasana, Pablo E. Vivas-Mejía, Marienid Flores-Colón, Irma Estefanía Ancira-Moreno, Patricio Adrián Zapata-Morín, Claudia Altamirano-Torres, José Manuel Vázquez-Guillen, Cristina Rodríguez-Padilla, Recep Bayraktar, Mohamed H. Rashed, Cristina Ivan, Gabriel Lopez-Berestein, Diana Reséndez-Pérez

“…Furthermore, inhibiting miR-660-5p led to notable decreases in the proliferation, migration, and invasion of breast cancer cells, as well as angiogenesis, in HUVEC cells. Through bioinformatics analysis, we identified 15 potential targets of miR-660-5p. …”
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Endothelial progenitor cell-derived conditioned medium mitigates chronic cerebral ischemic injury through macrophage migration inhibitory factor-activated AKT pathway by Ya-Wen Cheng, Ling-Yu Yang, Yi-Tzu Chen, Sheng-Che Chou, Kuo-Wei Chen, Yi-Hsing Chen, Chuan-Rou Deng, I-Chin Chen, Wan-Ju Chou, Chen-Chih Chang, Yong-Ren Chen, Hsiao-Lin Hwa, Kuo-Chuan Wang, Meng-Fai Kuo

“…Recombinant MIF protein promoted angiogenesis and prevented senescence in the injured EPCs and ECs. …”
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Engineered biomimetic nanovesicles-laden multifunctional hydrogel enhances targeted therapy of diabetic wound by Shuoyuan Liu, Gui Wan, Tao Jiang, Chengqi Yan, Guoyong Jiang, Maojie Zhang, Kaituo Xiang, Chi Zhang, Xuejiao Xiang, Huayuan Zhao, Chengcheng Li, Zhichao Ruan, Yangyang Chen, Yanhua Chen, Xiaofan Yang, Zhenbing Chen

“…Angiogenesis is essential for diabetic wound healing. …”
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Overexpression of Notch3 and pS6 Is Associated with Poor Prognosis in Human Ovarian Epithelial Cancer by Zhaoxia Liu, Rongna Yun, Xiaolin Yu, Hui Hu, Genhua Huang, Buzhen Tan, Tingtao Chen

“…In conclusion, Notch3 and pS6 are significantly related to ovarian epithelial cancer development and prognosis, and their combination represents a potential biomarker and therapeutic target in ovarian tumor angiogenesis.…”
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The Role of Matrix Metalloproteinases in the Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma by Cristian Scheau, Ioana Anca Badarau, Raluca Costache, Constantin Caruntu, Gratiela Livia Mihai, Andreea Cristiana Didilescu, Carolina Constantin, Monica Neagu

“…Matrix metalloproteinases (MMPs) play significant roles in cellular regeneration, programmed death, angiogenesis, and many other essential tissular functions, involved in the normal development and also in pathological processes, such as the EMT. …”
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Comparison of two graft procedures in a bilateral sinus lift by MRI and histomorphometric analysis: a case report by Maglione Michele, Michelon Filippo, Bevilacqua Lorenzo, Bertolotto Michele, Rothweiler René

“…CE-MRI was performed to evaluate angiogenesis before surgery and at 11, 25, 53, and 104 days after surgery. …”
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Circ_0008035 Promotes Gastric Cancer Development via the miR-429/SMAD2 Cascade by Yan Chen, Weigang Bian, Surong Chen

“…Cell cycle progression, apoptosis, angiogenesis, migration, and invasion were analyzed using flow cytometry, Tube formation, and Transwell assays respectively. …”
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Hepatocyte Growth Factor Effects on Mesenchymal Stem Cells Derived from Human Arteries: A Novel Strategy to Accelerate Vascular Ulcer Wound Healing by Sabrina Valente, Carmen Ciavarella, Emanuela Pasanisi, Francesca Ricci, Andrea Stella, Gianandrea Pasquinelli

“…This study was aimed at verifying whether HGF/SF influences proliferation, migration, and angiogenesis on mesenchymal stem cells isolated from human arteries (hVW-MSCs). hVW-MSCs were exposed to NIBSC HGF/SF (2.5, 5, 10, and 70 ng/mL) from 6 hrs to 7 days. …”
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Molecular Targeted Enhanced Ultrasound Imaging of Flk1 Reveals Diagnosis and Prognosis Potential in a Genetically Engineered Mouse Prostate Cancer Model by Jim W. Xuan, Michael Bygrave, Fatma Valiyeva, Madeleine Moussa, Jonathan I. Izawa, Glenn S. Bauman, Alexander Klibanov, Fen Wang, Norman M. Greenberg, Aaron Fenster

“…This report aimed at testing the possibility that Flk1 + (vascular endothelial growth factor receptor 2), a crucial angiogenesis factor of most tumor cells, could be a molecular targeted imaging marker for the diagnosis and prognosis of cancer. …”
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Stachydrine targeting tumor-associated macrophages inhibit colorectal cancer liver metastasis by regulating the JAK2/STAT3 pathway by Yang Gui, Gengchen Xue, Yuyi Yuan, Jingbo Wang, Shuangjiao Deng, Fei Gao, Yushi Tian, Zhiqiang Zhao, Heng Fan

“…In vitro, STA has been found to impede tumor cell migration, invasion, and angiogenesis by preventing TAMs from polarizing to the M2 phenotype via the JAK2/STAT3 signaling pathway. …”
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The Formation of Human Arteriovenous Malformation Organoids and Their Characteristics by Eun Jung Oh, Hyun Mi Kim, Suin Kwak, Chanhoe Huh, Ho Yun Chung

“…Genes such as FSTL1, associated with angiogenesis, showed significantly higher expression in the AVM organoids than in the normal organoids. …”
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miR-126 and miR-126*: New Players in Cancer by Jeannette Meister, Mirko H. H. Schmidt

“…Cancer progression is characterized by autarky in growth signals, insensitivity to growth-restrictive signals, evasion of apoptosis, a limitless potential to replicate, sustained angiogenesis, and tissue invasion, including metastasis. …”
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Metabolomic, transcriptomic and genetic integrative analysis reveals important roles of adenosine diphosphate in haemostasis and platelet activation in non‐small‐cell lung cancer... by Long T. Hoang, Clara Domingo‐Sabugo, Elizabeth S. Starren, Saffron A.G. Willis‐Owen, Deborah J. Morris‐Rosendahl, Andrew G. Nicholson, William O. C. M. Cookson, Miriam F. Moffatt

“…The important roles of adenosine diphosphate in promoting cancer metastasis through platelet activation and angiogenesis suggest this metabolite could be a potential therapeutic target.…”
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Quercetin-encapsulated GelMa hydrogel microneedle reduces oxidative stress and facilitates wound healing by Yi Yi, Zihui Yang, Chuchao Zhou, Yanqing Yang, Yiping Wu, Qi Zhang

“…In vitro, the physical properties, cell safety, cell migration, angiogenesis, collagen formation, and oxidative stress levels, were performed to characterize Q-MNs. …”
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