Amyloid-Beta Induced Changes in Vesicular Transport of BDNF in Hippocampal Neurons by Bianca Seifert, Robert Eckenstaler, Raik Rönicke, Julia Leschik, Beat Lutz, Klaus Reymann, Volkmar Lessmann, Tanja Brigadski

“…Transport of BDNF was altered at a very early time point after onset of human APP expression or after acute amyloid-beta(1-42) treatment, while the activity-dependent release of BDNF remained unaffected. …”
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Intraneuronal binding of amyloid beta with reelin-Implications for the onset of Alzheimer's disease. by Asgeir Kobro-Flatmoen, Stig W Omholt

“…Numerous studies of the human brain supported by experimental results from rodent and cell models point to a central role for intracellular amyloid beta (Aβ) in the onset of Alzheimer's disease (AD). …”
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An approach to predict and inhibit Amyloid Beta dimerization pattern in Alzheimer’s disease by Sreekanya Roy, Sima Biswas, Anirban Nandy, Dipanjan Guha, Rakhi Dasgupta, Angshuman Bagchi, Parames Chandra Sil

“…Amyloid plaques are rich in Amyloid Beta (Aβ) proteins, which are found in the brains of Alzheimer’s patients. …”
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Retinal Levels of Amyloid Beta Correlate with Cerebral Levels of Amyloid Beta in Young APPswe/PS1dE9 Transgenic Mice before Onset of Alzheimer’s Disease by Xi Mei, Mengxiang Yang, Lina Zhu, Qi Zhou, Xingxing Li, Zhongming Chen, Chenjun Zou

“…Retina abnormalities are related to cognitive disorders in patients with Alzheimer’s disease (AD). Retinal amyloid beta (Aβ) can be labeled by curcumin. We measured Aβ content in the cerebrum and retina of APPswe/PS1dE9 (APP) transgenic mice with early age to investigate the correlation between cerebrum and retina. …”
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Misfolded amyloid-beta conformational variants (strains) as drivers of Alzheimer’s disease neuropathology by Salvatore Saieva, Rodrigo Morales

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Zinc Metalloproteinases and Amyloid Beta-Peptide Metabolism: The Positive Side of Proteolysis in Alzheimer's Disease by Mallory Gough, Catherine Parr-Sturgess, Edward Parkin

“…Alzheimer's disease is a neurodegenerative condition characterized by an accumulation of toxic amyloid beta- (A𝛽-)peptides in the brain causing progressive neuronal death. …”
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Anti-Amyloid Imaging Abnormality in the Era of Anti-Amyloid Beta Monoclonal Antibodies: Recent Updates for the Radiologist by So Yeong Jeong, Chong Hyun Suh, Jae-Sung Lim, Yangsean Choi, Ho Sung Kim, Sang Joon Kim, Jae-Hong Lee

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Inhibitory Effect of Curcumin-Cu(II) and Curcumin-Zn(II) Complexes on Amyloid-Beta Peptide Fibrillation by Rona Banerjee

“…Mononuclear complexes of Curcumin with Cu(II) and Zn(II) have been synthesized and, characterized and their effects on the fibrillization and aggregation of amyloid-beta (Aβ) peptide have been studied. FTIR spectroscopy and atomic force microscopy (AFM) observations demonstrate that the complexes can inhibit the transition from less structured oligomers to β-sheet rich protofibrils which act as seeding factors for further fibrillization. …”
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Inhibitory potential against oral squamous cancer cells demonstrated by amyloid beta peptide (s)/doxorubicin (DOX) conjugates by Rethinam Senthil

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Systematic review of amyloid-beta clearance proteins from the brain to the periphery: implications for Alzheimer’s disease diagnosis and therapeutic targets by Letian Huang, Mingyue Liu, Ze Li, Bing Li, Jiahe Wang, Ke Zhang

“…Amyloid-beta clearance plays a key role in the pathogenesis of Alzheimer’s disease. …”
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Thioflavin-T: application as a neuronal body and nucleolar stain and the blue light photo enhancement effect by Jin-Hong Min, Heela Sarlus, Sho Oasa, Robert A. Harris

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Lipidopathy disrupts peripheral and central amyloid clearance in Alzheimer's disease: Where are our knowledge by Shahram Darabi, Enam Alhagh Charkhat Gorgich, Fatemeh Moradi, Auob Rustamzadeh

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Xixin Decoction’s novel mechanism for alleviating Alzheimer’s disease cognitive dysfunction by modulating amyloid-β transport across the blood–brain barrier to reduce neuroinflamma... by Chaokai Yang, Enlong Zhao, Hu Zhang, Liqi Duan, Xinyue Han, Hongli Ding, Yan Cheng, Dengkun Wang, Dengkun Wang, Dengkun Wang, Xiaojing Lei, Xiaojing Lei, Xiaojing Lei, Yongchang Diwu, Yongchang Diwu, Yongchang Diwu

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Molecular Mechanisms of Alzheimer’s Disease Induced by Amyloid-β and Tau Phosphorylation Along with RhoA Activity: Perspective of RhoA/Rho-Associated Protein Kinase Inhibitors for... by Eun Hee Ahn, Jae-Bong Park

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Screening of Aβ and phosphorylated tau status in the cerebrospinal fluid through machine learning analysis of portable electroencephalography data by Masahiro Hata, Yuki Miyazaki, Kohji Mori, Kenji Yoshiyama, Shoshin Akamine, Hideki Kanemoto, Shiho Gotoh, Hisaki Omori, Atsuya Hirashima, Yuto Satake, Takashi Suehiro, Shun Takahashi, Manabu Ikeda

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Blood-based biomarkers and plasma Aβ assays in the differential diagnosis of Alzheimer’s disease and behavioral-variant frontotemporal dementia by Pablo Mohaupt, Jana Kindermans, Jérôme Vialaret, Sarah Anderl-Straub, Leonie Werner, Sylvain Lehmann, Christophe Hirtz, Markus Otto, Patrick Oeckl

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SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer’s disease by Mridula Bhalla, Jinhyeong Joo, Daeun Kim, Jeong Im Shin, Yongmin Mason Park, Yeon Ha Ju, Uiyeol Park, Seonguk Yoo, Seung Jae Hyeon, Hyunbeom Lee, Junghee Lee, Hoon Ryu, C. Justin Lee

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Sex differences in the relationships between 24-h rest-activity patterns and plasma markers of Alzheimer’s disease pathology by Maxime Van Egroo, Elise Beckers, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Heidi I. L. Jacobs

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Association of a BACE1 Gene Polymorphism with Parkinson’s Disease in a Norwegian Population by Johannes Lange, Kristin Aaser Lunde, Camilla Sletten, Simon Geir Møller, Ole-Bjørn Tysnes, Guido Alves, Jan Petter Larsen, Jodi Maple-Grødem

“…Parkinson’s disease (PD) and Alzheimer’s disease (AD) share pathological features, including amyloid-beta pathology. Amyloid-beta peptide is generated by sequential proteolysis of amyloid precursor protein (APP), and genetic variations in the processing pathway genes have been found to increase the risk of AD; however, the contribution in PD is unknown. …”
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Pharmacological Modulation of Three Modalities of CA1 Hippocampal Long-Term Potentiation in the Ts65Dn Mouse Model of Down Syndrome by Jonah J. Scott-McKean, Adriano L. Roque, Krystyna Surewicz, Mark W. Johnson, Witold K. Surewicz, Alberto C. S. Costa

“…Whereas ≥10 μM picrotoxin increased LTP to control levels, it also caused seizure-like oscillations. Neither amyloid beta oligomers nor rPrP had any effect on 4xHFS-induced LTP in Ts65Dn-derived slices.…”
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