Low Infection Rate after Tumor Hip Arthroplasty for Metastatic Bone Disease in a Cohort Treated with Extended Antibiotic Prophylaxis by Werner H. Hettwer, Peter Frederik Horstmann, Thea Bechmann Hovgaard, Tomas Andreas Grum-Scwensen, Michael M. Petersen

“…The overall infection rate was 3.6% (4/111 implants), infection free survival was 96% at 2 years, and the risk of amputation associated with infection was 25% (1/4 patients). …”
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The Effect of Combination Foot Massage and Active Range of Motion (ROM) on Foot Sensitivity among Patients with Type 2 Diabetic Mellitus by I Made Cahyadi Agastiya, Ni Ketut Romani, I Made Artana

“…This increases the risk of diabetic foot ulcers, causing the patient to not feel any injuries to the legs, even to amputation. Therefore, handling the proper treatment to prevent these complications is necessary, one of which is using foot massage and active ROM. …”
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Suppurative Flexor Tenosynovitis: A Case Report by Pramono Ari Wibowo, M.D., Arham Adnani

“…Postoperative results were good, with no signs of complications such as spread of infection, tendon necrosis, osteomyelitis, or indications for amputation. Discussion: The treatment for suppurative flexor tenosynovitis involves a combination of antibiotics and surgery. …”
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Preventive interventions for diabetic foot ulcer adopted in different healthcare settings: A scoping review protocol. by Açucena Leal de Araújo, Francisca Diana da Silva Negreiros, Raquel Sampaio Florêncio, Thiago Dos Santos Garces, Virna Ribeiro Feitosa Cestari, Samuel Miranda Mattos, Samara Jesus Sena Marques, Francisca Eridan Fonteles Albuquerque, Wánderson Cássio Oliveira Araújo, Vanessa de Brito Poveda, Thereza Maria Magalhães Moreira

“…<h4>Background</h4>Diabetic foot ulcers are challenging to heal, increase the risk of lower extremity amputation, and place a significant burden on patients, families, and healthcare systems. …”
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Trends in diabetes mellitus and related costs among hospital admissions in Switzerland, 2012–2020 by Hassan Abu Obaid, Pedro Marques-Vidal

“…Compared to non-DM hospitalizations, all types of DM had a higher likelihood of lower limb amputation; hospitalizations for T1DM had a higher likelihood of ICU admission: odds ratio and 95% CI: 3.38 (3.19–3.59), while T2DM had higher LOS: 5.5 ± 1.0 vs. 5.1 ± 1.0 days, and all DM types had a lower odds of in-hospital mortality. …”
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Rituximab Efficacy during a Refractory Polyarteritis Nodosa Flare by Emmanuel Ribeiro, Thomas Cressend, Pierre Duffau, Marieke Grenouillet-Delacre, Marie Rouanet-Larivière, Anne Vital, Maïté Longy-Boursier, Patrick Mercié

“…Systemic vasculitis relapses are followed to accelerated atherosclerosis: severe ischemic lesions led to amputation of lower limbs. Remission of refractory PAN is obtained with rituximab. …”
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Autologous Stem Cell Therapy in Critical Limb Ischemia: A Meta-Analysis of Randomized Controlled Trials by Baocheng Xie, Houlong Luo, Yusheng Zhang, Qinghui Wang, Chenhui Zhou, Daohua Xu

“…Meta-analysis showed that cell therapy significantly increased the probability of ulcer healing (RR = 1.73, 95% CI = 1.45–2.06), angiogenesis (RR = 5.91, 95% CI = 2.49–14.02), and reduced the amputation rates (RR = 0.59, 95% CI = 0.46–0.76). Ankle-brachial index (ABI) (MD = 0.13, 95% CI = 0.11–0.15), TcO2 (MD = 12.22, 95% CI = 5.03–19.41), and pain-free walking distance (MD = 144.84, 95% CI = 53.03–236.66) were significantly better in the cell therapy group than in the control group (P<0.01). …”
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Outcome of Limb-sparing Surgery with Custom Mega Endoprosthesis Reconstruction for Bone Tumors in a Tertiary Care Center—10-year Study: Where Do We Stand? by Subbiah Shanmugam, Pravenkumar R Ramaswami

“…After re-surgery, either a second limb-sparing procedure or amputation, 49 patients (89.1%) retained their limb. …”
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Does Melanoma Begin in a Melanocyte Stem Cell? by James D. Hoerter, Patrick Bradley, Alexandria Casillas, Danielle Chambers, Brandon Weiswasser, Lauren Clements, Sarah Gilbert, Albert Jiao

“…Zebrafish have a robust regenerative capability, permitting the study of how MSCs are regulated and recruited at specific times and places to generate the pigment pattern following fin amputation or melanocyte ablation. They can be used to determine the effects of environmental radiation on the proliferation, survival, repair, and differentiation of MSCs. …”
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Distal Femur Allograft Prosthetic Composite Reconstruction for Short Proximal Femur Segments following Tumor Resection by Bryan S. Moon, Nathan F. Gilbert, Christopher P. Cannon, Patrick P. Lin, Valerae O. Lewis

“…One pt (8%) had an amputation and one pt (8%) died prior to union. Average time to union was 19 months. …”
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&#039;I cut toenails with scissors and trim it with sand paper&#039;. Patients&rsquo; perspectives on diabetic foot complications by Suliana Saverio, Masoud Mohammadnezhad, Filimone Raikanikoda

“…This will help guide patients to make life-altering decisions that can help reduce the rate of diabetes related lower limb amputations, which are easily preventable. …”
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Patients Undergoing Subacute Physical Rehabilitation following an Acute Hospital Admission Demonstrated Improvement in Cognitive Functional Task Independence by Steven M. McPhail, Paul N. Varghese, Suzanne S. Kuys

“…Consecutive rehabilitation admissions (n=814) following acute hospitalization (study criteria excluded orthopaedic, neurological, or amputation admissions). Intervention. Usual rehabilitation care. …”
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Domestic Horse Bite: An Unusual Etiology of Crush Injury of the Fourth Finger—How to Manage? by Naoufal Elghoul, Youssef Jalal, Ayoub Bouya, Ali Zine, Abdeloihab Jaafar

“…An excisional debridement of devitalized tissue with copious irrigation was performed, and the finger regularized at the level of traumatic amputation with tendon striping followed by coverage of the bone by the radial digital flap with careful clinical and biological monitoring after the surgery. …”
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Stromal-Cell-Derived Factor-1 (SDF-1)/CXCL12 as Potential Target of Therapeutic Angiogenesis in Critical Leg Ischaemia by Teik K. Ho, X. Shiwen, D. Abraham, J. Tsui, D. Baker

“…In a large percentage of these patients, lower limb amputation is still required. Studies of ischaemic skeletal muscle disclosed evidence of endogenous angiogenesis and adaptive skeletal muscle metabolic changes in response to hypoxia. …”
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Pengembangan Deep Learning untuk Sistem Deteksi Dini Komplikasi Kaki Diabetik Menggunakan Citra Termogram by Medycha Emhandyksa, Indah Soesanti, Rina Susilowati

“…Abstract The prevalence of diabetic foot complications globally reaches 66% with a 20 times higher risk of amputation in patients with diabetes mellitus. Preventive measures through early detection of diabetic foot complications are necessary to minimize the risk of amputation. …”
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Association between clinical and sonographic patterns of major peripheral arterial occlusion among patients presenting with lower limb dry gangrene at a single center in Western Ug... by Alfred Omo, Emmanuel Barasa, Edson Tayebwa, Moses Acan, Emile Ndanga, Aturinde Mercy

“…It is among the leading indications for lower limb amputation; however, in situations where timely access of accurate diagnostic and revascularization services are limited, irrational amputations are performed based on mere physical assessment of a specific occluded major arterial segment, consequently preceded with gangrene recurrence on the same limb stump due to physical examination inaccuracies. …”
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Fibrinogen: A Marker in Predicting Diabetic Foot Ulcer Severity by X. H. Li, L. Y. Guan, H. Y. Lin, S. H. Wang, Y. Q. Cao, X. Y. Jiang, Y. B. Wang

“…Using ROC statistic, a cut-off value of 5.13 g/L indicated the possible amputation with a sensitivity of 81.8% and a specificity of 78.9% (positive predictive value [PPV] 78.6%, negative predictive value [89.0%]). …”
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A one-two punch of inflammation and oxidative stress promotes revascularization for diabetic foot ulcers by Li Chen, Yunrong Li, Xuanxuan Zhang, Lixin Ma, Cheng Zhang, Huanhuan Chen

“…Patients with diabetic foot ulcers (DFU) suffering from severe lower limb ischemia face the risk of amputation. Concomitant oxidative stress and hyperinflammation commonly manifest within the tissue affected by DFU, exacerbating the deterioration of DFU wounds. …”
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Digital Gangrene: An Unusual Manifestation of Non-Hodgkin Lymphoma by Muhammad Shoaib Momen Majumder, Shamim Ahmed, Tajkia Haque, Syed Atiqul Haq, Saumitra Chakravarty, Md. Abu Shahin, Din-E-Mujahid Mohammad Faruque Osmany, Johannes J. Rasker

“…The digital ischemia worsened despite cessation of cannabis and methamphetamine and starting CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisolone) treatment, making amputation necessary. Conclusion. We present, to our knowledge, the first report of peripheral T cell lymphoma, NOS presenting with gangrene in all digits complicated by methamphetamine and cannabis abuse. …”
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OSTEOSARCOMA HAS NOT BECOME ATTENTION TO SOCIETY PROFILE OF OSTEOSARCOMA PATIENTS AT DR. SOETOMO GENERAL HOSPITAL SURABAYA "A RETROSPECTIVE STUDY” by Ferdiansyah Mahyudin, Mouli Edward, Muhammad Hardian Basuki, Yunus Abdul Bari, Yesa Suwandani

“…Osteosarcoma treated mostly by amputation, either with or without chemotherapy. The survival rate in the first, second, or the fifth year was found lower than other references. …”
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