Afasia primaria progresiva: aproximación clínica a un complejo síndrome neurobiológico by Silvia Gil-Navarro

“…Su sustrato neuropatológico se asocia mayoritariamente a la degeneración lobar frontotemporal y a la enfermedad de Alzheimer. Conforme la enfermedad evoluciona, se aprecia diseminación de la patología (a nivel intrahemisférico y contralateral) y aparición de síntomas extralingu?…”
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Specificity of Cognitive Impairment in Neurological Disease: A Methodological Critique of Parkinson’s Disease by H. J. Sagar

“…Sometimes, a relationship has been established between certain cognitive deficits and particular neurochemical deficits which has led to the notion of specific drug treatment, e.g. cholinergic deficits and memory failure in Alzheimer's disease. However, these conclusions are often potentially flawed by methodological inadequacies. …”
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Hsp70 and Its Molecular Role in Nervous System Diseases by Giuseppina Turturici, Gabriella Sconzo, Fabiana Geraci

“…Hsp70 functions as a chaperone and protects neurons from protein aggregation and toxicity (Parkinson disease, Alzheimer disease, polyglutamine diseases, and amyotrophic lateral sclerosis), protects cells from apoptosis (Parkinson disease), is a stress marker (temporal lobe epilepsy), protects cells from inflammation (cerebral ischemic injury), has an adjuvant role in antigen presentation and is involved in the immune response in autoimmune disease (multiple sclerosis). …”
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HCNetlas: A reference database of human cell type-specific gene networks to aid disease genetic analyses. by Jiwon Yu, Junha Cha, Geon Koh, Insuk Lee

“…These methods find that systemic lupus erythematosus genes predominantly function in myeloid cells, and Alzheimer's disease genes mainly play roles in inhibitory and excitatory neurons. …”
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Chlamydophila pneumoniae Infection and Its Role in Neurological Disorders by Carlo Contini, Silva Seraceni, Rosario Cultrera, Massimiliano Castellazzi, Enrico Granieri, Enrico Fainardi

“…A growing body of evidence concerns the involvement of this pathogen in chronic neurological disorders and particularly in Alzheimer's disease (AD) and Multiple Sclerosis (MS). …”
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Dendrobium species regulate energy homeostasis in neurodegenerative diseases: a review by Feixuan Wang, Jingqiong Wan, Yangzhen Liao, Shangyu Liu, Yuan Wei, Zhen Ouyang

“…Furthermore, they reduce neurotoxicity, alleviate brain injury and neuropathy, and prevent neurodegenerative conditions including stroke, Alzheimer's disease, Parkinson's disease, and Huntington's disease in humans and/or rodents. …”
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Roles of Brain Angiotensin II in Cognitive Function and Dementia by Masaki Mogi, Jun Iwanami, Masatsugu Horiuchi

“…Particularly, in dementia, epidemiological studies indicate a preventive effect of RAS blockade on cognitive impairment in Alzheimer disease (AD). Moreover, basic experiments suggest a role of brain angiotensin II in neural injury, neuroinflammation, and cognitive function and that RAS blockade attenuates cognitive impairment in rodent dementia models of AD. …”
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Amyloid β Enhances Typical Rodent Behavior While It Impairs Contextual Memory Consolidation by Karla Salgado-Puga, Roberto A. Prado-Alcalá, Fernando Peña-Ortega

“…Alzheimer’s disease (AD) is associated with an early hippocampal dysfunction, which is likely induced by an increase in soluble amyloid beta peptide (Aβ). …”
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Proton Pump Inhibitors and Dementia: Physiopathological Mechanisms and Clinical Consequences by Gloria Ortiz-Guerrero, Diana Amador-Muñoz, Carlos Alberto Calderón-Ospina, Daniel López-Fuentes, Mauricio Orlando Nava Mesa

“…Alzheimer’s disease (AD) is the most common type of dementia, mainly encompassing cognitive decline in subjects aged ≥65 years. …”
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Neuroprotective effect of olive leaf extract in the mouse neuroblastoma cell line (NB2a): A good model to evaluate the neuroprotective effects of natural products by Ercument Olmez, Ertan Dariverenli, Kamil Vural, Tugce Fafal, Dilek Gulce Tatli, Bijen Kivcak

“…Chronic neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases, whose prevalence increases with aging, cause serious health problems with inadequate treatment options. …”
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The use of ecological momentary assessment for family caregivers of adults with chronic conditions: A systematic review by Areum Han, Laurie A. Malone, Hee Yun Lee, Jiaqi Gong, Ryan Henry, Xishi Zhu, Hon K. Yuen

“… # Results A total of 12 studies involving EMA completed by family caregivers of adults with chronic conditions were identified, with almost all studies focused on caregivers of persons with Alzheimer's or dementia-related conditions. The average compliance rate across the included studies was 75%, below the recommended rate. …”
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Susceptibility to Aneuploidy in Young Mothers of Down Syndrome Children by Lucia Migliore, Francesca Migheli, Fabio Coppedè

“…We also discuss the increased risk of developing Alzheimer's disease (AD) later in life that was observed in women who had a DS child at a young age. …”
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Weighted Mortality Method According to Multiple Causes of Death by Lisbeth Fernández González, Armando Humberto Seuc Jo, Carlos Antonio Rodríguez García

“…<strong><br />Results:</strong> diseases such as heart disease, dementia and Alzheimer's, malignant tumors and asthma did not show differences between the rates calculated by both methods; diseases such as primary essential hypertension, diabetes mellitus and pneumonia, showed important differences. …”
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BACE1 Is Necessary for Experience-Dependent Homeostatic Synaptic Plasticity in Visual Cortex by Emily Petrus, Hey-Kyoung Lee

“…Alzheimer’s disease (AD) is the most common form of age-related dementia, which is thought to result from overproduction and/or reduced clearance of amyloid-beta (Aβ) peptides. …”
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Stephania japonica Ameliorates Scopolamine-Induced Memory Impairment in Mice through Inhibition of Acetylcholinesterase and Oxidative Stress by Md. Yusuf Al-Amin, Amitav Lahiry, Rafia Ferdous, Md. Kamrul Hasan, Md. Abdul Kader, AHM Khurshid Alam, Zahangir Alam Saud, Md. Golam Sadik

“…Alzheimer’s disease (AD) is a progressive neurological disorder characterized by loss of memory and cognition. …”
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More than just a number: the gut microbiota and brain function across the extremes of life by Nathan D. Nuzum, Clara Deady, Sarah Kittel-Schneider, John F. Cryan, Siobhain M. O'Mahony, Gerard Clarke

“…In neurodegeneration research, strong causal evidence now links the gut microbiome to Alzheimer's (AD), and Parkinson's Disease (PD), as supported by human-to-animal transplantation studies. …”
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Posterior AD-Type Pathology: Cognitive Subtypes Emerging from a Cluster Analysis by Antonella Cappa, Nicoletta Ciccarelli, Eleonora Baldonero, Marialuisa Martelli, Maria Caterina Silveri

“…“Posterior shift” of the neuropathological changes of Alzheimer's disease (AD) produces a syndrome (posterior cortical atrophy) (PCA) dominated by high-level visual deficits. …”
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Classifying Dementia Using Local Binary Patterns from Different Regions in Magnetic Resonance Images by Ketil Oppedal, Trygve Eftestøl, Kjersti Engan, Mona K. Beyer, Dag Aarsland

“…We explored the use of 2D local binary pattern (LBP) extracted from FLAIR and T1 MR images of the brain combined with a Random Forest classifier in an attempt to discern patients with Alzheimer's disease (AD), Lewy body dementia (LBD), and normal controls (NC). …”
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Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM. by Frances M Bashore, Vittorio L Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J Bradshaw, Karolina A Rygiel, Tina M Leisner, Rod Chalk, Swati Mishra, C Andrew Williams, Opher Gileadi, Paul E Brennan, Jesse C Wiley, Jake Gockley, Gregory A Cary, Gregory W Carter, Jessica E Young, Kenneth H Pearce, Haian Fu, Emory-Sage-SGC TREAT-AD Center, Alison D Axtman

“…RNA sequencing and genetic data support spleen tyrosine kinase (SYK) and high affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) as putative targets to be modulated for Alzheimer's disease (AD) therapy. FCER1G is a component of Fc receptor complexes that contain an immunoreceptor tyrosine-based activation motif (ITAM). …”
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Metabolic enzyme inhibitory abilities, in vivo hypoglycemic ability of palmleaf raspberry fruits extracts and identification of hypoglycemic compounds by Jun Tan, Danshu Wang, Yu Lu, Yehan Wang, Zongcai Tu, Tao Yuan, Lu Zhang

“…This study aims to evaluate the potential of FPZ extracts prepared with different approaches in attenuating hyperglycemia, gout, Alzheimer's disease, and pigmentation, to obtain the enriching fraction and to identify the major active compounds. …”
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