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621
Comparative Analysis of Performance of Lemon Peel Powder and its Ash as Natural Coagulants in the Treatment of Surface Water.
Published 2025“…Additionally, studies have reported that some chemical coagulants (such as Aluminium salts) remain in the water after coagulation and may induce Alzheimer’s disease and similar health problems(S.Choubey, 2012). …”
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622
The Impact of Purinergic System Enzymes on Noncommunicable, Neurological, and Degenerative Diseases
Published 2018-01-01“…Among the best known of these diseases are atherosclerosis, hypertension, cancer, epilepsy, Alzheimer’s disease (AD), Parkinson’s disease (PD), and multiple sclerosis (MS). …”
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623
Sex-modulated association between thyroid stimulating hormone and informant-perceived anxiety in non-depressed older adults: Prediction models and relevant cutoff value
Published 2025-01-01“…Abstract The aim of this study was to assess the association between thyroid function and perceived anxiety in non-depressed older adults. Non-depressed Alzheimer’s Disease Neuroimaging Initiative (ADNI) participants with complete Thyroid Stimulating Hormone (TSH) and neuropsychiatric inventory (NPI/NPI-Q) were included. …”
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624
Acetylcholinesterase Inhibitory and Antioxidant Activity of the Compounds Isolated from Vanda roxburghii
Published 2021-01-01“…Vanda roxburghii has been used in traditional medicine to treat nervous system disorders including Alzheimer’s disease (AD). We reported earlier a high acetylcholinesterase inhibitory and antioxidant activity in the chloroform fraction of this plant. …”
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625
Wolfberry extracts inhibit Aβ1-42 aggregation and rescue memory loss of AD drosophila
Published 2020-03-01“…This study is to investigate the potential of wolfberry water extracts for the treatment of Alzheimer’s disease (AD) and the relationship between their anti-AD property and the geographic locations in China. …”
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626
Emerging targets of α-synuclein spreading in α-synucleinopathies: a review of mechanistic pathways and interventions
Published 2025-01-01“…Abstract α-Synucleinopathies constitute a spectrum of neurodegenerative disorders, including Parkinson’s disease (PD), Lewy body dementia (LBD), Multiple System Atrophy (MSA), and Alzheimer’s disease concurrent with LBD (AD-LBD). These disorders are unified by a pathological hallmark: aberrant misfolding and accumulation of α-synuclein (α-syn). …”
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627
Amyloid-Beta Induced Changes in Vesicular Transport of BDNF in Hippocampal Neurons
Published 2016-01-01“…Investigation of disease-related changes in BDNF transport might provide insights into the cellular mechanism underlying, for example, Alzheimer’s disease (AD). To analyze the role of BDNF transport in AD, live cell imaging of fluorescently labeled BDNF was performed in hippocampal neurons of different AD model systems. …”
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628
The Neuroprotective Effect of Cornus mas on Brain Tissue of Wistar Rats
Published 2014-01-01“…Flavonoid derivatives as nonenzymatic antioxidants are important in the pathophysiology of many diseases including neurological disorders (e.g., Alzheimer’s disease) or heart disease. In this study, we examined the effect of an addition of freeze-dried fruit of cornelian cherry on three types of diets: control diet, fructose diet, and diet enriched in fats (high-fat diet). …”
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629
Synthesis of Arginase Inhibitors: An Overview
Published 2025-01-01“…In recent decades, the abnormal expression of ARG-1 or ARG-2 has been reported to be increasingly linked to a variety of diseases, including cardiovascular disease, inflammatory bowel disease, Alzheimer’s disease, and cancer. Therefore, considering the current relevance of this topic and the need to address the growing demand for new and more potent ARG inhibitors in the context of various diseases, this review was conceived. …”
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630
Modular cone-and-plate device for mechanofluidic assays in Transwell inserts
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631
Exploring the Association Between Overactive Bladder (OAB) and Cognitive decline: mediation by depression in elderly adults, a NHANES weighted analysis
Published 2025-01-01“…Cognitive health was assessed using the Consortium to Establish a Registry for Alzheimer’s Disease-Word Learning (CERAD W-L), Animal Fluency Test (AFT), and Digit Symbol Substitution Test (DSST). …”
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632
Hyperhomocysteinemia-induced VCID results in visual deficits, reduced neuroinflammation and vascular alterations in the retina
Published 2025-01-01“…A number of studies have looked at the effect of Alzheimer’s disease (AD) pathology on the retina and the associations of AD with visual deficits. …”
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633
Mutations in human prion-like domains: pathogenic but not always amyloidogenic
Published 2024-12-01“…To date, over 60 mutations targeting the LCDs of hnRNPs have been identified and associated with a spectrum of neurodegenerative diseases including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and Alzheimer’s disease (AD). The cryo-EM structures of pathological and functional fibrils formed by different hnRNPs have been recently elucidated, including those of hnRNPA1, hnRNPA2, hnRNPDL-2, TDP-43, and FUS. …”
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634
Sex differences in the association between repetitive negative thinking and neurofilament light
Published 2024-11-01“…., worry and ruminative brooding) is associated with biomarkers of Alzheimer’s disease. Given that women have a greater risk of many neurodegenerative diseases, this study investigated whether worry and brooding are associated with general neurodegeneration and whether associations differ by sex. …”
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635
Dysregulation of Metabolic Peptides in the Gut–Brain Axis Promotes Hyperinsulinemia, Obesity, and Neurodegeneration
Published 2025-01-01“…Furthermore, we review the potential links between these conditions and neuroinflammation and the development of neurodegenerative diseases like dementia, specifically Parkinson’s disease and Alzheimer’s disease.…”
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636
Differential Fasting Plasma Glucose and Ketone Body Levels in GHRKO versus 3xTg-AD Mice: A Potential Contributor to Aging-Related Cognitive Status?
Published 2017-01-01“…Since the majority of brain nutrients come from the periphery, this study examined whether the capacity to regulate peripheral glucose levels and KB production differs in animals with successful cognitive aging (growth hormone receptor knockouts, GHRKOs) versus unsuccessful cognitive aging (the 3xTg-AD mouse model of Alzheimer’s disease). Animals were fasted for 5 hours with their plasma glucose and KB levels subsequently measured. …”
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637
APOE4 and sedentary lifestyle synergistically impair neurovascular function in the visual cortex of awake mice
Published 2025-01-01“…Abstract Reduced cerebral blood flow occurs early in the development of Alzheimer’s disease (AD), but the factors producing this reduction are unknown. …”
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638
A Comparison of Computational Approaches for Intron Retention Detection
Published 2022-03-01“…We also describe the use of differential analysis methods to identify disease-associated IRs and compare differential IRs along with their Gene Ontology enrichment, which is illustrated on an Alzheimer’s disease RNA-Seq dataset. We discuss key principles and features of existing approaches and outline their differences. …”
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639
XGBoost-enhanced ensemble model using discriminative hybrid features for the prediction of sumoylation sites
Published 2025-02-01“…Identifying sumoylation sites is particularly important due to their links to Parkinson’s and Alzheimer’s. This study introduces XGBoost-Sumo, a robust model to predict sumoylation sites by integrating protein structure and sequence data. …”
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640
Environmental Factors Promoting Neural Plasticity: Insights from Animal and Human Studies
Published 2017-01-01“…There are patients with advanced neurodegeneration, such as Alzheimer’s disease (AD), that, despite this, have mild cognitive impairment. …”
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