Rheological monitoring of tau protein polymerisation with acoustic waves sensor by P. Didier, F. Razan, E. Caplain, M. Michiel, C. Delamarche, C. Nogues, J.Y. Le Huerou, S. Serfaty, P. Larzabal

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Reducing neonatal Fc receptor binding enhances clearance and brain-to-blood ratio of TfR-delivered bispecific amyloid-β antibody by Eva Schlein, Ken G. Andersson, Tiffany Dallas, Stina Syvänen, Dag Sehlin

Subjects: “…Alzheimer’s disease (AD)…”
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RatDEGdb: a knowledge base of differentially expressed genes in the rat as a model object in biomedical research by I. V. Chadaeva, S. V. Filonov, K. A. Zolotareva, B. M. Khandaev, N. I. Ershov, N. L. Podkolodnyy, R. V. Kozhemyakina, D. A. Rasskazov, A. G. Bogomolov, E. Yu. Kondratyuk, N. V. Klimova, S. G. Shikhevich, M. A.  Ryazanova, L. A. Fedoseeva, О. Е. Redina, О. S. Kozhevnikova, N. A. Stefanova, N. G. Kolosova, A. L. Markel, M. P. Ponomarenko, Yu. D. Oshchepkov

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Calcium bridges built by mitochondria-associated endoplasmic reticulum membranes: potential targets for neural repair in neurological diseases by Yichen Peng, Li Zhou, Yaju Jin, Danli Wu, Na Chen, Chengcai Zhang, Hongpeng Liu, Chunlan Li, Rong Ning, Xichen Yang, Qiuyue Mao, Jiaxin Liu, Pengyue Zhang

Subjects: “…alzheimer’s disease…”
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Globular-shaped Aβ oligomers have diverse mechanisms for promoting Aβ aggregations with the facilitation of fibril elongation by Hiroto Nakano, Sadao Hikishima, Makoto Mori, Jota Minamikawa, Daiki Muramatsu, Yasuhiro Sakashita, Tokuhei Ikeda, Moeko Noguchi-Shinohara, David B. Teplow, Kenjiro Ono

Subjects: “…Alzheimer's disease…”
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Effectiveness and utilization of a cognitive screening program for primary geriatric care by David P. Salmon, Anna Malkina, Melanie L. Johnson, Christina Gigliotti, Emily A. Little, Douglas Galasko

“…Alzheimer’s Research & Therapy…”
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Timing of risk factors, prodromal features, and comorbidities of dementia from a large health claims case–control study by Stefan Teipel, Manas Akmatov, Bernhard Michalowsky, Steffi Riedel-Heller, Jens Bohlken, Jakob Holstiege

“…Alzheimer’s Research & Therapy…”
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Inflammatory biomarkers profiles and cognition among older adults by Aline Thomas, Jing Guo, Dolly Reyes-Dumeyer, Danurys Sanchez, Nikolaos Scarmeas, Jennifer J. Manly, Adam M. Brickman, Rafael A. Lantigua, Richard Mayeux, Yian Gu

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Female Sprague Dawley Rats Show Impaired Spatial Memory in the 8-Arm Radial Maze under Dim Blue and Red Light by Michael Pirchl, Georg Kemmler, Christian Humpel

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The regulatory role of cystatin C in autophagy and neurodegeneration by T. A. Korolenko, A. B. Shintyapina, A. B. Pupyshev, A. A. Akopyan, G. S. Russkikh, M. A. Dikovskaya, V. A. Vavilin, E. L Zavjalov, M. A. Tikhonova, T. G. Amstislavskaya

“…It has been suggested that cystatin C plays the primary role in amyloidogenesis and shows promise as a therapeutic agent for neurodegenerative diseases (Alzheimer’s and Parkinson’s diseases). Cystatin C colocalizes with the amyloid β-protein in the brain during Alzheimer’s disease. …”
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Decoding the molecular, cellular, and functional heterogeneity of zebrafish intracardiac nervous system by Andrea Pedroni, Elanur Yilmaz, Lisa Del Vecchio, Prabesh Bhattarai, Inés Talaya Vidal, Yu-Wen E. Dai, Konstantinos Koutsogiannis, Caghan Kizil, Konstantinos Ampatzis

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Enhancing NMDA Receptor Function: Recent Progress on Allosteric Modulators by Lulu Yao, Qiang Zhou

“…In light of the discovery of NMDAR hypofunction in psychiatric disorders and perhaps Alzheimer’s disease, efforts in boosting NMDAR activity/functions have surged in recent years. …”
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Phosphodiesterase-5 Inhibitors: Action on the Signaling Pathways of Neuroinflammation, Neurodegeneration, and Cognition by Christina Alves Peixoto, Ana Karolina Santana Nunes, Ana Garcia-Osta

“…Mechanistically, PDE5-Is produce an anti-inflammatory and neuroprotection effect by increasing expression of nitric oxide synthases and accumulation of cGMP and activating protein kinase G (PKG), the signaling pathway of which is thought to play an important role in the development of several neurodiseases, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and multiple sclerosis (MS). …”
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Quercetin nanoparticles as a therapeutic approach: pharmacological actions and potential applications in therapy by Reham Farouk El-Sayed Baiomy

“…It also highlights their potential as therapeutic agents in treating a wide range of diseases, including Alzheimer’s disease, cancer, and neurodegenerative disorders.…”
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Genotoxicity Studies of Titanium Dioxide Nanoparticles (TiO2NPs) in the Brain of Mice by Hanan R. H. Mohamed, Nahed A. Hussien

“…Moreover, Comet assay revealed the apoptotic DNA fragmentation, while PCR-SSCP pattern and direct sequencing showed point mutation of Presenilin 1 gene at exon 5, gene linked to inherited forms of the Alzheimer’s disease. Therefore, from these findings, the present study concluded that TiO2NPs is genotoxic and mutagenic to brain tissue which in turn might lead to Alzheimer’s disease incidence.…”
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An overview of methods for the treatment and diagnosis of dementia with Lewy bodies. Clinical case analysis by M. Š. Markevičiūtė, M. Karnickas, A. Bagdonaitė

“…Although DLB is the third most common type of dementia in the elderly, after Alzheimer’s disease and vascular dementia, it is still too rarely diagnosed. …”
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Oxidative stress induced protein aggregation via GGCT produced pyroglutamic acid in drug resistant glioblastoma by Deanna Tiek, Xiao Song, Xiaozhou Yu, Runxin Wu, Rebeca Iglesia, Alicia Catezone, Katy McCortney, Jordain Walshon, Craig Horbinski, Pouya Jamshidi, Rudolph Castellani, Robert Vassar, Jason Miska, Bo Hu, Shi-Yuan Cheng

“…Finally, we found increased protein aggregation, GGCT expression, and pyroglutamic acid staining in recurrent GBM patient samples, adjacent non-tumor brain, and Alzheimer’s brains. These findings suggest a new pathway for protein aggregation within drug resistant brain cancer that should be further studied in other brain disorders.…”
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Loss of MEF2C function by enhancer mutation leads to neuronal mitochondria dysfunction and motor deficits in mice by Ali Yousefian-Jazi, Suhyun Kim, Jiyeon Chu, Seung-Hye Choi, Phuong Thi Thanh Nguyen, Uiyeol Park, Min-gyeong Kim, Hongik Hwang, Kyungeun Lee, Yeyun Kim, Seung Jae Hyeon, Hyewhon Rhim, Hannah L. Ryu, Grewo Lim, Thor D. Stein, Kayeong Lim, Hoon Ryu, Junghee Lee

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Assessing the Impact of Physical Activity on Dementia Progression Using Clustering and the MRI-Based Kullback–Leibler Divergence by Agnieszka Wosiak, Małgorzata Krzywicka, Katarzyna Żykwińska

“…Dementia, including Alzheimer’s disease, is a neurodegenerative illness characterized by the progressive impairment of cognitive functions, posing a significant global health threat. …”
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Chemical Profiles and In Vitro Cholinesterase Inhibitory Activities of the Flower Extracts of Cassia spectabilis by null Suciati, Erlinda R. Laili, Wiwied Ekasari, null Kuatman, Nitra Nuengchamnong, Nungruthai Suphrom

“…The water and ethanolic extracts of C. spectabilis flowers displayed potency for Alzheimer’s disease treatment. The presence of piperidine alkaloids in the extract may be responsible for the cholinesterase inhibitory activity. …”
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