Status of the GRANIT Facility by Damien Roulier, Francis Vezzu, Stefan Baeßler, Benoît Clément, Daniel Morton, Valery V. Nesvizhevsky, Guillaume Pignol, Dominique Rebreyend

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Generation of Inducible CRISPRi and CRISPRa Human Stromal/Stem Cell Lines for Controlled Target Gene Transcription during Lineage Differentiation by Li Chen, Kaikai Shi, Weimin Qiu, Lars Aagaard, Moustapha Kassem

“…In the presence of Dox, the expression of ALP showed 60-90% inhibition in hMSC-CRISPRi while ALP showed more than 20-fold increased expression in hMSC-CRISPRa. …”
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How fast is the frequency of precipitation extremes doubling in global land regions? by Guillaume Chagnaud, Juliette Blanchet, Guillaume Evin, Benoit Hingray, Thierry Lebel, Geremy Panthou, Théo Vischel

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Subekoregije in bioregije celinskih voda Slovenije by Gorazd Urbanič

“…Ustreznost členitev smo preverjali s statistično metodo nemetričnega multidimenzionalnega skaliranja. Hidroekoregijo Alpe smo členili na dve subhidroekoregiji: Alpe-donavsko porečje in Alpe-jadransko povodje. …”
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A new framework for shallow approximations of incompressible flows by Shourick, Nathan, Cheddadi, Ibrahim, Saramito, Pierre

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Early Osteogenic Differentiation Stimulation of Dental Pulp Stem Cells by Calcitriol and Curcumin by Mohammad Samiei, Atefeh Abedi, Simin Sharifi, Solmaz Maleki Dizaj

“…Early osteogenic differentiation was evaluated and confirmed by the gene expression level of ALP and its activity. Curcumin individually and in combination with calcitriol increased ALP activity and osteoblast-specific mRNA expression of ALP when DPSCs were cultured in an osteogenic medium. …”
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Zona incerta: from Parkinson's disease to addiction by Mylène Wilt, Robin Magnard, Sebastien Carnicella, Yvan M. Vachez

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A genomic duplication spanning multiple P450s contributes to insecticide resistance in the dengue mosquito Aedes aegypti by Bacot, Tiphaine, Haberkorn, Chloe, Guilliet, Joseph, Cattel, Julien, Kefi, Mary, Nadalin, Louis, Filee, Jonathan, Boyer, Frederic, Gaude, Thierry, Laporte, Frederic, Tutagata, Jordan, Vontas, John, Dusfour, Isabelle, Bonneville, Jean-Marc, David, Jean-Philippe

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Effect of diet containing alfalfa (Medicago sativa) powder and leaf extract on hemolymph factors of western whiteleg shrimp (Litopenaeus vannamei) under low salinity stress by Kobra Babanejad Abkenar, Arash Akbarzadeh, Ahmad Noori, Mohammad Niroomand

“…Materials and methods: Shrimp were fed in seven treatments with three replications, including control (without ALP and ALE), ALP (60, 120, and 180 g/kg), and ALE (6, 12, and 18 g/kg) for nine weeks. …”
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Top 10 palliative care research priorities in France: a 3-step, mixed-methods protocol (AXEPRO study) by Stéphane Sanchez, Guillaume Economos, Fiona Ecarnot, Cecile Barbaret, Raphaëlle Habert-Dantigny, Héloïse Rouze, Doan Huynh, Roseline Huynh, Caroline Tête, Martin Julier-Costes, Valérie Amouroux-Gorsse, Isabelle Lavault, Justine Bret

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Response to Statin Therapy in Obstructive Sleep Apnea Syndrome: A Multicenter Randomized Controlled Trial by Marie Joyeux-Faure, Renaud Tamisier, Jean-Philippe Baguet, Sonia Dias-Domingos, Stephen Perrig, Georges Leftheriotis, Jean-Paul Janssens, Wojciech Trzepizur, Sandrine H. Launois, Françoise Stanke-Labesque, Patrick A. Lévy, Frédéric Gagnadoux, Jean-Louis Pepin

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Liver Function-Related Indicators and Risk of Gallstone Diseases—A Multicenter Study and a Systematic Review and Meta-Analysis by Shiyi Li, Pei Zhu, Fangyuan Chen, Wenqian Yu, Linjun Xie, Jing Xia, Peng Jiao, Ping Cui, Chi Zhang, Ye Bai, Guoheng Jiang, Hongyu Li, Yanmei Lou, Guangcan Li, Xuefeng Shan, Xin Wang

“…Only the association between ALP and GSD risk was validated in the UKB cohort. …”
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Antioxidant, Antibacterial, and Cytoprotective Activity of Agathi Leaf Protein by A. S. Zarena, Shubha Gopal, R. Vineeth

“…In the present study a protein termed agathi leaf protein (ALP) from Sesbania grandiflora Linn. (agathi) leaves was isolated after successive precipitation with 65% ammonium sulphate followed by purification on Sephadex G 75. …”
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Co-designing conversational agents with older people: A scoping review of methods, challenges, and a way forward by Sidonie Salomé, Lydie Du Bousquet, Emmanuel Monfort

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The contrasted impacts of grasshoppers on soil microbial activities in function of primary production and herbivore diet by Ibanez, Sébastien, Foulquier, Arnaud, Brun, Charles, Colace, Marie-Pascale, Piton, Gabin, Bernard, Lionel, Gallet, Christiane, Clément, Jean-Christophe

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Comparative effects of different dietary pectin types on growth performance and intestinal health in pearl gentian grouper (Epinephelus fuscoguttatus♀ × E. lanceolatus♂) by Lulu Zhu, Xiaoxue Meng, Xuehan Wang, Jiongting Fan, Beiping Tan, Junming Deng

“…Four experimental diets were formulated, including an 8 % common low-ester pectin (CLP) diet, 8 % amidated low-ester pectin (ALP) diet, 8 % high-ester pectin (HP) diet, and a control diet in which 8 % pectin was replaced by 8 % dextrin. …”
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Assessing Contact Graph Routing Performance and Reliability in Distributed Satellite Constellations by J. A. Fraire, P. Madoery, S. Burleigh, M. Feldmann, J. Finochietto, A. Charif, N. Zergainoh, R. Velazco

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Axon regeneration: an issue of translation by Schaeffer, Julia, Belin, Stephane

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Cytokines TNF-α, IL-6, IL-17F, and IL-4 Differentially Affect Osteogenic Differentiation of Human Adipose Stem Cells by Angela P. Bastidas-Coral, Astrid D. Bakker, Behrouz Zandieh-Doulabi, Cornelis J. Kleverlaan, Nathalie Bravenboer, Tim Forouzanfar, Jenneke Klein-Nulend

“…TNF-α reduced collagen type I gene expression but increased hASC proliferation and ALP activity. IL-6 also strongly enhanced ALP activity (18-fold), as well as bone nodule formation by hASCs. …”
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Histological diagnosis of primary biliary cholangitis in one patient without cholestasis alterations: a case report that escaped guidelines by Matteo Biagi, Elisa Bernasconi, Carmela Cursaro, Enrico Ronconi, Filippo Zanni, Pamela Sighinolfi, Pietro Andreone

“…In contrast, this is the case of a patient with autoantibody positivity and both ALP and GGT within the range, diagnosed for PBC by histology. …”
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