Impact of long-term cyanotoxin exposure on cattle: Biochemical, histological, and oxidative stress assessment by Mounira Bensalem, Amina Amrani, Hadjer Zaidi, Fateh Sedrati, Omar Laouar, Zhi Wang, Hichem Nasri

“…Antioxidant enzyme activities (GPx, CAT and SOD) were reduced, with notable depletion of GSH levels and increased lipid peroxidation. …”
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Echinococcal Cyst Blockade — the Rare Cause of Acute Pancreatitis and Obstructive Jaundice by S. A. Budzinskiy, S. G. Shapovaliants, R. V. Plakhov, M. V. Murashkina, E. A. Vorobyeva, D. R. Berdieva, P. V. Usyaky, E. D. Fedorov

“…After non-annulation endoscopic papillotomy, migration of the substrate (echinococcal cyst) into the duodenum was noted, active flow of bile and pancreatic secretions was restored. …”
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Characterizing the deformation, failure, and water-conducting fractures evolution of shallow weakly cemented overburden under coal mining by Zhenhua Li, Yandong Zhang, Xuefeng Gao, Xuefeng Gao, Dan Ma, Dan Ma, Limin Fan, Guodong Li, Xiaolei Li, Min He, Zheng Cheng

“…Hence, we conducted a meter-scale similar physical model experiment using high-resolution digital speckle technology to replicate the deformation and failure patterns of shallowly buried, weakly cemented overburden under mining activities, and to determine the initiation, development, and stability of water-conducting fractures. …”
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Refining δ15N isotopic fingerprints of local NOx for accurate source identification of nitrate in PM2.5 by Hao Xiao, Qinkai Li, Shiyuan Ding, Wenjing Dai, Gaoyang Cui, Xiaodong Li

“…Here, we systematically determined and refined δ15N values for six categories of NOx sources in Tianjin using an active sampling method. Moreover, the δ15N values of NO3– in PM2.5 were measured during pre-heating, mid-heating and late-heating periods, which are the most heavily polluted in Tianjin. …”
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Hemorrhagic syndrome at liver cirrhosis by I. A. Kurkina, O. S. Volkova, M. V. Mayevskaya, V. T. Ivashkin

“…Standard complex tests for hemostasis lose their diagnostic value in this group of patients. Active search of the laboratory methods is conducted, allowing to estimate the risk of bleeding in liver cirrhosis patients. …”
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Development of therapeutic supplement using roasted-cashew-nut to protect cerebral vasoconstriction injury triggered by mixture of petroleum hydrocarbons in the hypothalamus and hi... by J.K. Akintunde, V.O. Akomolafe, R.N. Ugbaja, A.M. Olude, A.D. Folayan

“…Petroleum-related activities have been a health global risk concern, particularly in the limbic disorders. …”
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An Evidence-Based Update on the Impact of Local Antimicrobials as Adjunct to Periodontal Therapy by Nabaz Yahya Hussein, Sadat Abdulla Aziz, Twana Mohammed M. Ways, Omed Amiri, Hisham Al-Obaidi, Dianne Ford

“…CHX demonstrated the greatest clinical improvement due to its broad-spectrum antimicrobial activity, strong substantivity, and its application in sustained-release formulations. …”
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Molecular mechanisms of cis-oxygen bridge neonicotinoids to Apis mellifera Linnaeus chemosensory protein: Surface plasmon resonance, multiple spectroscopy techniques, and molecular... by Xiangshuai Li, Shiyu Li, Yang Liu, Li Cui, Daibin Yang, Shuning Chen, Xusheng Shao, Huizhu Yuan, Xiaojing Yan

“…Molecular docking and dynamics simulations further illustrated the stability of these interactions within the active site of the protein. Of particular interest, cis-structured neonicotinoids demonstrated distinct binding characteristics compared to their trans-structured counterparts, including an inverse relationship between the binding constant and temperature. …”
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The Treatment Effect of Plantago Major on Lung Cancer Based on the Computed Tomography and Pathological Findings: A Case Report Study by Saade Abdalkareem Jasim, Bashar Mudhaffar Abdullah, Patricio Yánez-Moretta, Wesam R. Kadhum, Yasser Fakri Mustafa, Enas R. Alwaily, Munther Abosoda, Ali Alsalamy, Sada Ghalib Al-Musawi, Alaa A. Omran

“… Purpose: Plantago Major (PM) is widely used for the treatment of different diseases due to several active compounds. Previous studies demonstrated the treatment effect of this plant on lung cancer cell lines. …”
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Genomic insights and comparative analysis of Colletotrichum species associated with anthracnose fruit rot and crown rot of strawberry in North Carolina by Tika B. Adhikari, Norman Muzhinji, Ashley N. Philbrick, Frank J. Louws, Frank J. Louws

“…The predicted gene models included effectors (339 to 480), secondary metabolic gene clusters (67 to 90), and carbohydrate-active enzymes (800 to 1,060), with C. siamense isolates exhibiting the highest numbers in these categories. …”
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Anaerobic metabolism promotes breast cancer survival via Histone-3 Lysine-18 lactylation mediating PPARD axis by Ying Xu, Weiwei Meng, Yingqi Dai, Lin Xu, Ning Ding, Jinqing Zhang, Xuewei Zhuang

“…During the proteomics analysis, AKT-phosphorylation in the aerobic respiration inhibitor group exhibited an apparent disparity and activity. Our study demonstrated that changes in H3K18la in BC and its downstream transcription factor PPARD support cell survival under anaerobic glycolysis conditions. …”
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Single cell RNA sequencing reveals human tooth type identity and guides in vitro hiPSC derived odontoblast differentiation (iOB) by Sesha Hanson-Drury, Sesha Hanson-Drury, Sesha Hanson-Drury, Anjali P. Patni, Anjali P. Patni, Anjali P. Patni, Anjali P. Patni, Deborah L. Lee, Deborah L. Lee, Deborah L. Lee, Ammar Alghadeer, Ammar Alghadeer, Ammar Alghadeer, Ammar Alghadeer, Yan Ting Zhao, Yan Ting Zhao, Yan Ting Zhao, Devon Duron Ehnes, Devon Duron Ehnes, Devon Duron Ehnes, Vivian N. Vo, Vivian N. Vo, Vivian N. Vo, Sydney Y. Kim, Sydney Y. Kim, Druthi Jithendra, Druthi Jithendra, Ashish Phal, Ashish Phal, Ashish Phal, Natasha I. Edman, Natasha I. Edman, Natasha I. Edman, Natasha I. Edman, Thomas Schlichthaerle, Thomas Schlichthaerle, David Baker, David Baker, David Baker, Jessica E. Young, Jessica E. Young, Julie Mathieu, Julie Mathieu, Hannele Ruohola-Baker, Hannele Ruohola-Baker, Hannele Ruohola-Baker, Hannele Ruohola-Baker, Hannele Ruohola-Baker

“…During human odontoblast development, computational analysis predicts that early FGF and BMP activation followed by later HH signaling is crucial. …”
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MYH9 promotes malignant progression of glioma cells through regulating β-catenin stability via epithelial-mesenchymal transition signaling pathway by Zigui Chen, Chao Liu, Wei Zheng, Zhilong Li, Yuanhui Tang, Jun Peng, Changfeng Miao, Dandan Zheng, Ying Xia

“…Abstract Epithelial‒mesenchymal transition (EMT) is a process in which polar epithelial cells transform into active mesenchymal cells and acquire invasion and migration capabilities (Cano CE, Motoo Y, Iovanna JL in Sci World J 10, 2010). …”
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Anti-allergic potentials of Ceriops decandra leaves in TDI-induced allergic mice: Comprehensive in-vivo and in-silico studies by Aishwarja Dey, Subarna Rani, Rabindra Nath Acharyya, Apurba Kumar Barman, Khondoker Shahin Ahmed, Nripendra Nath Biswas, Shrabanti Dev, Asish Kumar Das

“…Method: The toxicity was screened by mortality rate, and behavioral changes in mice. Anti-allergic activity test was conducted on TDI induced allergy model mice by assessing the common allergic symptoms such as sneezing, scratching, nasal score as well as total and differential WBC counts. …”
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Effects of different fertilization treatments on ground-dwelling arthropods and their functional groups in agricultural landscapes by Ziqi Bian, Ziqi Bian, Lyuyi Liu, Lyuyi Liu, Yan Li, Yan Li, Yanli Li, Yanli Li, Shengyan Ding, Shengyan Ding

“…Studying arthropod diversity, community structure, and soil physico-chemical properties under various fertilization treatments is crucial to understanding the impact of agricultural activities. We used pitfall traps to catch ground-dwelling arthropods four times a year, and analyzed arthropod abundance and biodiversity indices under different fertilization treatments The study revealed that Lycosidae and Araneidae were the dominant family in the study area. …”
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Genetic and pharmacological targeting of HINT2 promotes OXPHOS to alleviate inflammatory responses and cell necrosis in acute pancreatitis by Jiaqi Yao, Yuhong Jiang, Pengcheng Zhang, Yifan Miao, Xiajia Wu, Hang Lei, Zhijun Xie, Yong Tian, Xianlin Zhao, Juan Li, Lv Zhu, Meihua Wan, Wenfu Tang

“…Mechanistically, HINT2 interacted with cytochrome C oxidase II (MTCO2) to promote mitochondrial OXPHOS, thereby reducing ROS accumulation and inhibiting the activation of inflammatory signaling pathway. Besides, HINT2 act as a direct pharmacological target of Emo to elicit protective effects on AP. …”
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Heterogeneous graph convolutional neural network for protein-ligand scoring by Kevin Crampon, Alexis Giorkallos, Xavier Vigouroux, Stephanie Baud, Luiz Angelo Steffenel

“…Aim: Drug discovery is a long process, often taking decades of research endeavors. It is still an active area of research in both academic and industrial sectors with efforts on reducing time and cost. …”
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PTOV1 exerts pro-oncogenic role in colorectal cancer by modulating SQSTM1-mediated autophagic degradation of p53 by Yongli Fan, Yuqin Li, Xia Luo, Shiqi Xiang, Jia Hu, Jingchun Zhan, Weilong Chang, Rui Deng, Xianwen Ran, Yize Zhang, Yudie Cai, Weiwei Zhu, Huifen Wang, Zhibo Liu, Di Wang

“…At the molecular level, PTOV1 destabilized p53 by activating autophagy and recruiting p53 for the cargo receptor SQSTM1 directed autophagic degradation. …”
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Impact of interventions on mpox transmission during the 2022 outbreak in Canada: a mathematical modeling study of three different cities by Fanyu Xiu, Carla M. Doyle, Jorge Luis Flores Anato, Jesse Knight, Linwei Wang, Joseph Cox, Daniel Grace, Trevor A. Hart, Terri Zhang, Shayna Skakoon-Sparling, Milada Dvorakova, Rita Shahin, Herveen Sachdeva, Nathan Lachowsky, Hind Sbihi, Darrell H.S. Tan, Michael A. Irvine, Sharmistha Mishra, Mathieu Maheu-Giroux

“…Conclusions: Reduction in sexual activity, contact tracing/isolation, and vaccination all contributed to accelerating epidemic control. …”
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