Exploring the Genotype-Environment Interaction in Sugar Beet (Beta vulgaris L.) Genotypes for Optimal Selection by Mahdi Ramazi, Saeed Sadeghzadeh Hemayati, Heshmat Omidi, Amirmohammad Naji

“…Standard agricultural practices, including weed control, irrigation, fertilizer application, and other farm management activities, were implemented, throughout the cropping season. …”
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Longitudinal association between DNA methylation and type 2 diabetes: findings from the KORA F4/FF4 study by Liye Lai, Dave Laurence Juntilla, Monica Del, Monica Del C Gomez-Alonso, Harald Grallert, Barbara Thorand, Aiman Farzeen, Wolfgang Rathmann, Juliane Winkelmann, Holger Prokisch, Christian Gieger, Christian Herder, Annette Peters, Melanie Waldenberger

“…Abstract Background Type 2 diabetes (T2D) has been linked to changes in DNA methylation levels, which can, in turn, alter transcriptional activity. However, most studies for epigenome-wide associations between T2D and DNA methylation comes from cross-sectional design. …”
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Effects of <i>Enterococcus faecalis</i> Supplementation on Growth Performance, Hepatic Lipid Metabolism, and mRNA Expression of Lipid Metabolism Genes and Intestinal Flora in Geese by Siyu Sun, Yujie Zhao, Zhen Pang, Baoxia Wan, Jiaqi Wang, Zhenyu Wu, Qiuju Wang

“…Conversely, the mRNA expression levels of fatty acid synthase (FASN), farnesoid X receptor (FXR), sterol regulatory element-binding protein 1 (SREBP-1), and peroxisome proliferator-activated receptor-α (PPARα) were significantly elevated (<i>p</i> < 0.05). …”
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Development, implementation, and evaluation of an innovative clinical trial operations training program for Africa (ClinOps) by Dawit Asmamaw Ejigu, Abebaw Fekadu, Jeremy Whitty, Tsegahun Manyazewal, Pamela Nebeta, Almari Conradie, Brenda Okech, Alice Neequaye, Sinéad Whitty, Jennifer Lehrman, Renee Holt, Rahel Birhane, Mahnaz Vahedi, Helen Demarest, Eyasu Makonnen

“…Results In the initial cohort, 88 study coordinators from 19 countries participated, including 56 (64%) females, with 57 (65%) actively employed as study coordinators during the training, and 85 (97%) possessing prior experience in clinical trial roles. …”
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L’habituation des bonobos de la forêt de Manzano dans le Territoire de Bolobo (Province du Bandundu, RDC) : évolution du processus au regard du socio-écosystème by Victor Narat, Jean Christophe Bokika Ngawolo, Blanchard Bongwana, Sabrina Krief

“…L’habituation des bonobos de la forêt de Manzano a débuté en 2010 de manière active mais discontinue. Les bonobos sont recherchés sur une zone de 22 km2, et localisés à partir des vocalisations et des traces fraîches en parcourant des pistes. …”
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Annexin A8 deficiency delays atherosclerosis progression by Carmen Gutiérrez‐Muñoz, Rafael Blázquez‐Serra, Irene San Sebastian‐Jaraba, Sandra Sanz‐Andrea, Maria J. Fernández‐Gómez, Gonzalo Nuñez‐Moreno, Pablo Mínguez, Joan Carles Escolá‐Gil, Paula Nogales, Veronique Ollivier, Jose L. Martín‐Ventura, Benoit Ho‐Tin Noe, Ursula Rescher, Nerea Méndez‐Barbero, Luis M. Blanco‐Colio

“…Germline AnxA8 deficiency reduces platelet and leukocyte recruitment to activated endothelium as well as atherosclerotic burden, plaque size, and macrophage accumulation in mice. …”
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Assessment of Bowel Preparation Using Low-Volume Sulphate-Based Preparations in Comparison with Macrogols: A Multicenter, Randomized, Comparative Clinical Study of the 3rd Phase by E. D. Fedorov, V. V. Veselov, S. V. Kashin, E. V. Tikhomirova, A. V. Veselov, D. V. Zavyalov, A. Kornowski, T. E. Gorskaya, M. Volteau, T. Ponchon

“…The authors also express their appreciation to Olga Kapitonova, an employee of the Almedis company (Moscow, Russia) for her assistance in compiling medical texts, which activity was carried out under the financial support of the Ipsen company (Moscow, Russia) in accordance with the Good Publication Practice (GPP).…”
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Dynamics of HDL-Cholesterol Following a Post-Myocardial Infarction Cardiac Rehabilitation Program by Carlos Bertolín-Boronat, Héctor Merenciano-González, Víctor Marcos-Garcés, María Luz Martínez-Mas, Josefa Inés Climent Alberola, Nerea Pérez, Laura López-Bueno, María Concepción Esteban-Argente, María Valls Reig, Ana Arizón Benito, Alfonso Payá Rubio, César Ríos-Navarro, Elena de Dios, Jose Gavara, Juan Sanchis, Vicente Bodi

“…No significant correlations were found with Mediterranean diet adherence, weekly physical activity, training modalities, or physical fitness parameters. …”
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從「無感」到「五感」的環境意識啟蒙：特定場域劇場教學之批判教育學實踐 From “Indifference” to Environmental Conscientization Through Critical Sensory Pedagogy: A Critical Pedagogy Praxis in a University Site-Specifi... by 藍貝芝 Betsy Lan, 楊佳羚 Chia-Ling Yang

“…Students engaged with the lived realities of community residents and environmental movements through immersive activities such as press conferences and field trips. …”
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Influencing Mechanisms of Ecosystem Services on Net Carbon Sink Efficiency and Spatial Differentiation Thereof: A Case Study of the Shanghai Metropolitan Area by Haoyang SONG, Min WANG

“…As there are differences in the spillover effects of different ecosystem services, it is necessary to differentiate the optimization and enhancement strategies for each type of ecological space and its ecosystem services according to local conditions, and the conservation of important ecological spaces in the metropolitan area should be continuously strengthened, followed by joint protection and control of ecological red lines in neighboring areas, so as to promote territorial spatial carbon reduction and sink enhancement activities, thus contributing to the steady improvement of the net carbon sink efficiency of the Shanghai Metropolitan Area in general. …”
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Soluble and cell-based markers of immune checkpoint inhibitor-associated nephritis by Sandra M Herrmann, Riley Fadden, Ryan J Sullivan, Kerry L Reynolds, Harish Seethapathy, Meghan E Sise, Shruti Gupta, Alexandra-Chloe Villani, Qiyu Wang, Daiana Moreno, Destiny Harden, R Neal Smith, Ivy A Rosales, Robert B Colvin, Sarah Chute, Lynn D Cornell, Nancy J Yang, Sara Barmettler, Sophia Wells, Jocelyn Farmer

“…The downstream impact of T cell activation in the affected kidney was investigated using archived biopsy samples to evaluate the gene expression of IL2RA, IL-2 signaling, and T cell receptor signaling in patients with ICI-nephritis compared with other causes of drug-induced nephritis, acute tubular injury, and histologically normal controls.Results sIL-2R level in peripheral blood was significantly higher in patients with ICI-nephritis (N=24) (median 2.5-fold upper limit of normal (ULN), IQR 1.9–3.3), compared with ICI-treated controls (N=10) (median 0.8-fold ULN, IQR 0.5–0.9, p&lt;0.001) and hemodynamic AKI controls (N=6) (median 0.9-fold-ULN, IQR 0.7–1.1, p=0.008). …”
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Gut bacteria Prevotellaceae related lithocholic acid metabolism promotes colonic inflammation by Liping Chen, Zhenghao Ye, Junhua Li, Lijia Wang, Yu Chen, Meiping Yu, Jian Han, Jiangeng Huang, Dongyan Li, Yongling Lv, Kai Xiong, De’an Tian, Jiazhi Liao, Ursula Seidler, Fang Xiao

“…Subsequent experiments confirmed that LCA supplementation effectively mitigated the inhibitory effects of gut microbiota on colitis progression in mice, primarily through the activation of the sphingosine-1-phosphate receptor 2 (S1PR2)/NF-κB p65 signaling pathway. …”
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Effectiveness of hCMV, mEF1a and mAct promoters on driving of foreign gene expression in transgenic zebrafish by . Alimuddin, G. Yoshizaki, O. Carman, T. Takeuchi

“…Here, as the first step of study, we conducted experiment to select an appropriate construct that allows higher expression levels of masu salmon (Oncorhynchus masou) D6-desaturase gene in zebrafish (Danio rerio) in order to increase its activity for synthesizing EPA/DHA.  Salmon D6-desaturase cDNA (sD6) was separately ligated with human cytomegalovirus (hCMV), medaka elongation factor 1a (mEF1a) and medaka b-actin (mAct) promoters.  …”
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Association of depression in multiple sclerosis with fatigue, sleep disturbances, disability, and health-related quality of life: Outcomes of a cross-sectional study by E. Aparicio-Castro, A. Candeliere-Merlicco, C.M. Santa, R. Villaverde-González

“…Conclusion: This study underscores the prevalence and impact of depression in MS, emphasizing the importance of routine screening and active management of psychiatric comorbidities in individuals with MS. …”
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Multispecies probiotics applications through feed addition on cultured tilapia to prevent streptococcosis by Nurin Dalilah Ayu Destianingrum, Munti Yuhana, Angela Mariana Lusiastuti

“…The highest increased immune value shown by K3 were wich phagocytic index value 64.00±2.65% and respiratory burst activity value 0.07±0.00 OD.   Keywords: multispecies probiotics, Oreochormis niloticus, streptococcosis     ABSTRAK   Streptococcosis merupakan salah satu penyakit yang seringkali muncul dan dapat menyebabkan kematian hingga 100% pada budidaya ikan nila. …”
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Indoor, outdoor, and personal exposure to PM2.5 and associated health risk in community-dwelling elderly residents in Fuzhou city, 2021: a cross-sectional study by Shuling KANG, Xin LIN, Kan LIN, Baoying LIU, Chuancheng WU, Jianjun XIANG, Jingwen CHEN, Quan ZHOU

“…All participants were interviewed with a questionnaire on demographics, living conditions, health status, lifestyle behaviors, and activities during the PM2.5 sampling period. PM2.5 concentration was measured with the weighing method; polycyclic aromatic hydrocarbons (PAHs) and metal elemental components in collected PM2.5 were determined by ultra-high performance liquid chromatography and inductively coupled plasma mass spectrometry. …”
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Diagnostics and treatment of gastroesophageal reflux disease: clinical guidelines of the Russian gastroenterological association by V. T. Ivashkin, I. V. Mayev, I. . A.s. Trukhmanov, Ye. K. Baranskaya, O. B. Dronova, O. V. Zayratyants, R. G. Sayfutdinov, A. A. Sheptulin, T. L. Lapina, S. S. Pirogov, Yu. A. Kucheryavy, O. A. Storonova, D. N. Andreyev

“…Implementation of clinical guidelines can promote improvement of healthcare quality for GERD patients and prevent complications, in particular if terms of treatment will be observed, at active outpatient follow­up for certain groups of patients.…”
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Impact of Ketogenic and Mediterranean Diets on Gut Microbiota Profile and Clinical Outcomes in Drug-Naïve Patients with Diabesity: A 12-Month Pilot Study by Vanessa Palmas, Andrea Deledda, Vitor Heidrich, Giuseppina Sanna, Giulia Cambarau, Michele Fosci, Lorenzo Puglia, Enrico Antonio Cappai, Alessio Lai, Andrea Loviselli, Aldo Manzin, Fernanda Velluzzi

“…<b><b>Background/Objectives</b></b>: Managing type 2 diabetes mellitus (T2DM) and obesity requires a multidimensional, patient-centered approach including nutritional interventions (NIs) and physical activity. Changes in the gut microbiota (GM) have been linked to obesity and the metabolic alterations typical of T2DM and obesity, and they are strongly influenced by diet. …”
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Conocimientos, práctica y actitudes hacia la salud oral entre matronas de España by Yolanda Martínez-Beneyto, Andrea Poza Pascual, Cristina Carazo, Clara Serna-Muñoz, Amparo Pérez-Silva, Antonio José Ortiz-Ruiz

“…Methodology: A descriptive, observational, and cross-sectional study was conducted with active midwives in the Community of Murcia and Vizcaya. …”
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Sex determination and acclimation response of dwarf snakehead fish Channa limbata from West Java by Dinar Tri Soelistyowati, Agus Oman Sudrajat, Harton Arfah, Alimuddin Alimuddin, Riva Hafidah, Yudha Hanggara, Thomas Edison

“…Natural snakehead fishing activities have threatened its sustainability. Breeding C. limbata fish through cultivation can increase its potential for sustainable use. …”
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