Predictive effect of estimated glomerular filtrate rate by creatinine or cystatin C on mortality in patients with coronary artery disease by Shiqun Chen, Yang Zhou, Guoxiao Liang, Wanying Wu, Zhigang Huang, Lile Shi, Yuwei Gao, Xia Gu, Dongmei Wang

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Combined pyrotinib and fulvestrant for hormone receptor‐positive and HER2‐positive metastatic breast cancer: A multicenter, single‐arm, phase II trial by Jianli Zhao, Yunfang Yu, Wei Ren, Linxiaoxiao Ding, Yongjian Chen, Peng Yuan, Jian Yue, Yaping Yang, Guorong Zou, Tao Chen, Jie Chai, Li Zhang, Wenjing Wu, Yinduo Zeng, Xiujuan Gui, Yangyang Cai, Simin Luo, Zhongyu Yuan, Kang Zhang, Herui Yao, Ying Wang

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Efficacy and safety of the pulsed electromagnetic field in osteoarthritis: a meta-analysis by Ziying Wu, Xiang Ding, Guanghua Lei, Chao Zeng, Jie Wei, Jiatian Li, Hui Li, Tuo Yang, Yang Cui, Yilin Xiong, Yilun Wang, Dongxing Xie

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Design, synthesis, SAR and ADMET analyses of the novel class of synthetic 7-amino[1,2,5]oxadiazolo[3,4-b]pyridine-6-carboxylate derivatives with vasorelaxant activity by Anatolii Varenyk, Roman Vydzhak, Svitlana Panchishin, Irina Ivanova, Victor Zhirnov, Volodymyr Brovarets

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Machine learning based on blood test biomarkers predicts fast progression in advanced NSCLC patients treated with immunotherapy by Jie Yang, Jian-Guo Zhou, Benjamin Frey, Hu Ma, Haitao Wang, Markus Hecht, Rainer Fietkau, Udo Gaipl, Xiaofei Chen, Ada Hang-Heng Wong, Fangya Tan, Si-Si He, Gang Shen, Yun-Jia Wang, Wenzhao Zhong

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Resensitizing β‐Lactams by Reprogramming Purine Metabolism in Small Colony Variant for Osteomyelitis Treatment by Tingwang Shi, Qiong Wu, Zesong Ruan, Zhiyuan Luo, Wenbo Wang, Zhao Guo, Yihong Ma, Xin Wang, Guangyu Chu, Han Lin, Min Ge, Yunfeng Chen

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Preliminary study assessing the long-term surgical outcomes of TBX6-associated congenital scoliosis (TACS) patients using the propensity score matching method: exploring the clinic... by Guanfeng Lin, Yang Yang, Zefu Chen, Sen Zhao, Yuchen Niu, You Du, Yiwei Zhao, Shengru Wang, Nan Wu, Jianguo Zhang

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Association of Maternal Diabetes Mellitus and Polymorphisms of the NKX2.5 Gene in Children with Congenital Heart Disease: A Single Centre-Based Case-Control Study by Mingyi Zhao, Jingyi Diao, Peng Huang, Jinqi Li, Yihuan Li, Yang Yang, Liu Luo, Senmao Zhang, Letao Chen, Tingting Wang, Ping Zhu, Jiabi Qin

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Hei-Gu-Teng Zhuifenghuoluo Granule Modulates IL-12 Signal Pathway to Inhibit the Inflammatory Response in Rheumatoid Arthritis by Kang Zheng, Zexu Chen, Wen Sun, Bin Liu, Danping Fan, Qingqing Guo, Hui Luo, Jiawen Shen, Li Li, Xiaojuan He, Shuang Kou, Xiaoya Li, Guoming Pang, Hongchuan Zhao, Cheng Lu

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Diagnostic investigation, intervention, and outcome for post-subtotal gastrectomy patients who present with jaundice by Duan Wang, Duan Wang, Liang Zhu, Fanyi Kong, Fanyi Kong, Yingyu Pan, Yingyu Pan, Wei Liu, Xuan Wang, Weidong Pan, Jian Cao, Qiang Xu, Dong Wu, Dong Wu, Dong Wu

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Casual associations between frailty and nine mental disorders: bidirectional Mendelian randomisation study by Yong Zhou, Jiayue Duan, Jiayi Zhu, Yunying Huang, Tao Tu, Keke Wu, Qiuzhen Lin, Yingxu Ma, Qiming Liu

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Histone lysine crotonylation accelerates ACSL4-mediated ferroptosis of keratinocytes via modulating autophagy in diabetic wound healing by Fengjuan Li, Haowen Ye, Lanlan Li, Qingling Chen, Xianwu Lan, Liangxiu Wu, Bin Li, Lishan Li, Chuxian Guo, Milad Ashrafizadeh, Gautam Sethi, Jun Guo, Liangyan Wu

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Non-Luminal Disease Score for Everolimus in Patients with Hormone Receptor‑positive and Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: A Mult... by Tan Y, Jiang H, Tian X, Ma F, Wang J, Zhang P, Xu B, Fan Y, Zhao W

“…Yujing Tan,1,* Hanfang Jiang,2,* Xinzhu Tian,1,* Fei Ma,1 Jiayu Wang,1 Pin Zhang,1 Binghe Xu,1 Ying Fan,1 Weihong Zhao3 1Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100021, People’s Republic of China; 2Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Breast Oncology, Peking University Cancer Hospital & Institute, Beijing, 100142, People’s Republic of China; 3Department of Medical Oncology, Chinese PLA General Hospital, Beijing, 100853, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ying Fan; Weihong Zhao, Email fanying@cicams.ac.cn; zhaowh0818@163.comPurpose: This study aims to explore the role of the non-luminal disease score (NOLUS) for everolimus in patients with hormone receptor-positive and human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced breast cancer (ABC).Methods: NOLUS has previously been established as an algorithm: NOLUS (0– 100) = − 0.45 × ER(%) − 0.28 × PR(%) + 0.27 × Ki67(%) + 73. …”
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Identification of therapeutic target genes for age-related hearing loss through systematic genome-wide mendelian randomization of druggable genes by Kun Zhang, Bo Hou, Tao Yan, Ruru Qiao, Peng Qu, Xinbo Xu, Hanbing Zhang

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Upregulated astrocyte HDAC7 induces Alzheimer-like tau pathologies via deacetylating transcription factor-EB and inhibiting lysosome biogenesis by Jinwang Ye, Suyue Zhong, Huali Wan, Xing Guo, Xuanbao Yao, Qiong Liu, Liming Chen, Jian-Zhi Wang, Shifeng Xiao

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Linear association between high-sensitivity C-reactive protein and postoperative delirium after general anesthesia: a cross-sectional study by Xiao Qin, Junming Ren, Chunping Xing, Lijiao Chen, Renjie Wang, Shouyuan Tian

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Dietary Magnesium Intake and Leukocyte Telomere Attrition in Adults: The Regulatory Role of Serum Tumor Necrosis Factor α by Jie Yu, Haibin Liu, Shuli He, Pingping Li, Chunxiao Ma, Minglei Ma, Yiwen Liu, Lu Lv, Fan Ping, Huabing Zhang, Wei Li, Qi Sun, Lingling Xu, Yuxiu Li

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Multiparameter body composition analysis on chest CT predicts clinical outcomes in resectable non-small cell lung cancer by Yilong Huang, Hanxue Cun, Zhanglin Mou, Zhonghang Yu, Chunmei Du, Lan Luo, Yuanming Jiang, Yancui Zhu, Zhenguang Zhang, Xin Chen, Bo He, Zaiyi Liu

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Early-life famine exposure may modify the association between long-term temperature variability and cardio-cerebrovascular diseases: a nationwide study by Yao Wu, BinBin Su, Junqing Xie, Bo Wen, Xiaolan Wu, Mengfan Wang, Yanhui Dong, Yi Song, Jun Ma

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Clinical Characteristics and Optimization of Empirical Antimicrobial Therapy for Febrile Neutropenia in Patients With Hematologic Malignancies by Cui Y, Liu X, Feng S

“…Yuqing Cui,1,2 Xin Liu,1,2 Sizhou Feng1,2 1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, 300020, People’s Republic of China; 2Tianjin Institutes of Health Science, Tianjin, 300020, People’s Republic of ChinaCorrespondence: Sizhou Feng, Email doctor_szhfeng@163.comPurpose: Since the publication of the 2011 Infectious Diseases Society of America (IDSA) guidelines for empirical treatment of febrile neutropenia (FN), there have been significant shifts in pathogen profiles and emerging challenges in treatment. …”
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