Assessment of Tumor Burden Score as a Feasible and Reliable Tool for Prognosis Prediction for Hepatocellular Carcinoma Undergoing Hepatectomy: A Multicenter, Retrospective Study by Guan R, Zheng Z, Deng M, Mei J, Lin Y

“…Tumor burden score (TBS) shows its distinguished ability to stratify patients with HCC undergoing transcatheter arterial chemoembolization (TACE). …”
Get full text

A Prospective Randomized Study for Comparison of Modified Proximal Femoral Plate with Dynamic Hip Screw System by Jitendra Wadhwani, Ramchander Siwach, Himanshu Bansal, Roop Singh, Pradeep Kamboj, Hemant More

“…It is an angular stable construct with the ability to achieve compression across the fracture site. …”
Get full text

Investigating the Feasibility of Behavioral Nudges to Reduce the Phenomenon of Escape from Responsibility in Public Sector by Seyed Kamal Vaezi, Mahboubeh Hosseini

“…This study showed that, according to Iranian experts, the motivational nudges, responsive nudges, and ethically based nudges have a greater and more effective ability to influence the handling of escape from responsibility in public sectors.…”
Get full text

PENGARUH PEMBELAJARAN MODEL PROBLEM SOLVING BERORIENTASI HIGHER ORDER THINKING SKILLS TERHADAP HASIL BELAJAR FISIKA DAN KEMAMPUAN PEMECAHAN MASALAH by Safri Daryanti, Indra Sakti, Dedy Hamdani

“…Based on results of research, it can be concluded that there is an influence of HOTS-oriented Problem Solving learning model on physics learning outcomes and improve students Problem Solving abilities.   Keywords: Problem Solving, Higher Order Thinking Skills (HOTS), Physics Learning Outcomes, Problem Solving Abilities …”
Get full text

The effect of molecular structure of chlorin photosensitizers on photo-bleaching of 1,3-diphenylisobenzofuran—the possible evidence of iodine reactive species formation by Kustov, Andrey, Morshnev, Philipp, Kukushkina, Natal’ya, Krestyaninov, Mikhail, Smirnova, Nataliya, Berezin, Dmitry, Kokurina, Galina, Belykh, Dmitry

“…In this short communication, we focus on the ability of chlorin e$_{6}$ photosensitizers (PSs) with one, two or three cationic groups to generate singlet oxygen species ($^{1}$O$_{2}$) in an apolar model medium, viz. 1-octanol (OctOH). …”
Get full text

Factors that influence the adoption of a school-based eHealth alcohol prevention program among Spanish personnel: a mixed methods study by Ester Alejandra Rosado-Pulido, Pablo Fernández-León, Marta Lima-Serrano, Hein de Vries

“…Intenders perceived a higher personal relevance and responsibility towards using the program, more self-efficacy (e.g., ability to understand, manage time and incorporate the program) and positive social influences from their colleagues, as well as greater willingness in preparing action plans, such as monitor students’ alcohol consumption and discussing the program with coworkers, than the non-intenders group. …”
Get full text

FoxA1 knockdown promotes BMSC osteogenesis in part by activating the ERK1/2 signaling pathway and preventing ovariectomy-induced bone loss by Lijun Li, Renjin Lin, Yang Xu, Lingdi Li, Zhijun Pan, Jian Huang

“…Furthermore, our approach can distinguish genes that exhibit osteogenic differentiation characteristics. This ability can aid in the identification of novel genes associated with osteogenic differentiation, which can be utilized in the treatment of osteoporosis. …”
Get full text

Translation, content validity and internal structure of the Brazilian version of the Adolescent Resilience Questionnaire (B-ARQ). by Genara Brum Gomes, Luisa Gatti-Reis, Matheus França Perazzo, Marisa Alves Araújo, Flávio Freitas Mattos, Deirdre Gartland, Saul Martins Paiva, Isabela Almeida Pordeus

“…Resilience refers to one's ability to face life's challenges and achieve positive outcomes, and has drawn increasing interest from researchers and policymakers. …”
Get full text

Shift from chronic to episodic migraine frequency in a long-term phase 3 study of galcanezumab by Hans-Christoph Diener, Kathleen A. Day, Sarah Lipsius, Sheena K. Aurora, Nada A. Hindiyeh, Holland C. Detke

“…Galcanezumab is a monoclonal antibody to calcitonin gene-related peptide which is approved for the preventive treatment of migraine. Ability to convert patients from chronic migraine frequency to episodic migraine (EM) frequency is a clinically relevant and desirable outcome when prescribing preventive treatments to patients with CM. …”
Get full text

Smart Pharmaceutical Monitoring System With Personalized Medication Schedules and Self-Management Programs for Patients With Diabetes: Development and Evaluation Study by Jian Xiao, Mengyao Li, Ruwen Cai, Hangxing Huang, Huimin Yu, Ling Huang, Jingyang Li, Ting Yu, Jiani Zhang, Shuqiao Cheng

“…Individualized medication schedules and self-management programs were generated based on patient-specific conditions and needs, using an app framework to build patient-side contact pathways. The system’s ability to provide medication guidance and health management was assessed by senior health care professionals using a 5-point Likert scale across 3 groups: outputs generated by the system (DUMS group), outputs refined by pharmacists (intervention group), and outputs generated by ChatGPT-4 (GPT-4 group). …”
Get full text

Immune profiling of human vestibular schwannoma secretions identifies TNF-α and TWEAK as cytokines with synergistic potential to impair hearing by Sasa Vasilijic, Richard Seist, Zhenzhen Yin, Lei Xu, Konstantina M. Stankovic

“…Methods To identify effector molecules involved in VS-induced SNHL, we analyzed 47 immune-related factors secreted by tumor tissue in over 50 patients with sporadic VS and studied their correlation with preoperative hearing ability and tumor size. The most promising effector molecules were validated in vivo in an anatomically accurate mouse model of VS, and in vitro with mouse fibroblasts (L929) and auditory cell lines representing pro-sensory precursors of hair cells (UB-OC1) and auditory neuroblasts (US-VOT-N33). …”
Get full text

Circular RNA encoded by PPARG in the peripheral blood and a lipopolysaccharide-induced cardiomyocyte inflammation model is identified as a marker of fulminant myocarditis by Shasha Huang, Shumin He, Fei Xiao, Yang Zhou, Su Lyu

“…ROC curve analysis showed that the level of circ_PPARG in peripheral blood had a good ability to distinguish patients with FM from healthy controls. …”
Get full text

Bioinformatics insights into mitochondrial and immune gene regulation in Alzheimer's disease by Tian Meng, Yazhou Zhang, Yuan Ye, Hui Li, Yongsheng He

“…Results Using machine learning algorithms, five biomarkers (TSPO, HIGD1A, NDUFAB1, NT5DC3, and MRPS30) were successfully identified, and a nomogram model with strong diagnostic ability and accuracy (AUC > 0.9) was constructed. …”
Get full text

The role of natural exosomes from SHED-MSC in immunoregulation of M0/M1 polarized macrophage cells by Ali Fallah, Abasalt Hosseinzadeh Colagar, Ayyoob Khosravi, Ayyoob Khosravi, Azadeh Mohammad-Hasani, Azadeh Mohammad-Hasani, Mohsen Saeidi, Mohsen Saeidi

“…These nanovesicles, with their distinct physical properties and ability to penetrate target cells, may prove beneficial in conditions involving the depletion of M2 macrophages and M1 macrophage-induced diseases, potentially aiding in the reduction of inflammation and tissue injury.…”
Get full text

Teknik Representasi Kebutuhan Pengguna Menggunakan User Persona (Studi Kasus: Relasi antara Presensi dengan Kemampuan Kompetensi) by Wahyu Andhika, Muhammad Iqbal, Munifah Nur, Rizkhi Dwi Nugroho

“…This method will help describe a persona in depth ranging from personality, ability to persona behavior towards a problem. The detailed persona document is then concluded in order to obtain a basic requirement to be implemented into a system. …”
Get full text

Effects of poultry by-product meal and complete replacement of fish oil with alternative oils on growth performance and gut health of rainbow trout (Oncorhynchus mykiss): a FEEDNET... by Imam Hasan, Simona Rimoldi, Biagina Chiofalo, Marianna Oteri, Micaela Antonini, Rosangela Armone, Violeta Kalemi, Laura Gasco, Genciana Terova

“…Conclusions The FEEDNETICS™ application enhances our ability to optimize feeding strategies and improve production efficiency in the aquaculture industry. …”
Get full text

Post-treatment of rat aflatoxicosis by camel milk and silymarin by Nahla H. Hassaneen, Shabaan A. Hemeda, Abeer F. El Nahas, Ghadeer M. Albadrani, Muath Q. Al-Ghadi, Zuhair M. Mohammedsaleh, Sabreen E. Fadl, Eman M. El-Diasty, Hader I. Sakr, Hader I. Sakr

“…Moreover, the histopathology of the liver and testes was done along with expression levels of specific genes in the liver and testes.ResultsThe outcomes showed that the post-treatment with silymarin and camel milk improved biochemical markers in serum and ability to reproduce.ConclusionIn conclusion, post-treatment with camel milk and silymarin could mitigate the negative effect of AFB1 on rats.…”
Get full text

HUBUNGAN ANTARA KEMAMPUAN BERPIKIR KRITIS DENGAN HASIL BELAJAR MELALUI MODEL INKUIRI TERBIMBING by Wahyu Youllanda, Rosane Medriati, Eko Swistoro

“…The results of the study, data analysis and hypothesis testing showed that there is a positive correlation between the ability to think critically with student learning outcomes through the guided inquiry model in class X MIPA SMA N 4 Bengkulu City that is 0.607 which is in the high category and the magnitude of the relationship obtained is 36.89 %.   …”
Get full text

Alternatives to Traditional Physical Science Laboratory Experiences: A Review by Mercy Ogunsola-bandele, Dietmar Kennepohl

“…This is evidenced by conflicting research reports on students’ ability to manipulate laboratory equipment after participating in online experimentation. …”
Get full text

Incorporating insulin into alginate-chitosan 3D-printed scaffolds: A comprehensive study on structure, mechanics, and biocompatibility for cartilage tissue engineering by Afsaneh Jahani, Mohammad Sadegh Nourbakhsh, Ali Moradi, Marzieh Mohammadi, Lobat Tayebi

“…Cartilage tissue engineering (CTE) integrates cells, scaffolds, and signaling molecules, with Insulin being utilized as a differentiation biomolecule due to cost-effectiveness, dose-dependent influence on chondrogenesis, suitable biological activity, and ability to activate relevant receptors. Yet, administering differentiation biomolecules through conventional scaffolds poses a persistent challenge. …”
Get full text