Diisooctyl phthalate (DIOP) exposure leads to cell apoptosis to HUVEC cells and toxicity to Caenorhabditis elegans through increasing the oxidative stress by Siyuan Luo, Junnan Li, Yuqing Zhou, Zihang Zhai, Qiang Li, Zhenglin Huang, Wencan He, Kejun Zhong, Bo Kong, Zanxian Xia, Hang Fai Kwok, Lipeng Zhu

“…Our results demonstrate that DIOP markedly decreases the viability and colony-forming ability of HUVECs. Moreover, this cytotoxicity correlates with elevated levels of reactive oxygen species (ROS), causing cell cycle arrest at the G1 phase and the induction of cell apoptosis. …”
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Enhanced vehicle routing for medical waste management via hybrid deep reinforcement learning and optimization algorithms by Norhan Khallaf, Osama Abd-El Rouf, Abeer D. Algarni, Mohy Hadhoud, Ahmed Kafafy

“…Despite this trade-off, the algorithm’s ability to minimize fleet size while fully utilizing vehicle capacity makes it the optimal choice in scenarios where these factors are critical. …”
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Breeding for Heat Tolerant Aromatic Rice Varieties and Identification of Novel QTL Regions Associated with Heat Tolerance During Reproductive Phase by QTL-Seq by Surangkana Chimthai, Sulaiman Cheabu, Wanchana Aesomnuk, Siriphat Ruengphayak, Siwaret Arikit, Apichart Vanavichit, Chanate Malumpong

“…Therefore, our objective was to develop heat-tolerant aromatic rice varieties using the pedigree method, focusing on selecting for seed-setting ability under extremely high temperatures along with the use of single nucleotide polymorphism/insertion and deletion (SNP/InDel) markers to improve aromatic properties and grain quality. …”
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Guar gum-modified magnetic palladium nanocatalyst: C–N coupling reaction and STAT3-Mediated breast cancer therapy by Junrui Luan, Xin Dong, Shuwen Zhou

“…In addition, the new accelerator bears the ability to be recuperated and recycled 7 times. The MTT test was then used to investigate the extent to which Fe3O4@guar gum/Pd NP-treated cells suppressed human breast cancer. …”
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Own Experience in the Use of Artificial Intelligence Technologies in the Diagnosis of Esophageal Achalasia by O. A. Storonova, N. I. Kanevskii, A. S. Trukhmanov, V. T. Ivashkin

“…The model has been applied to the creation of a web application which has the ability to substantiate the manometry diagnosis of patients. …”
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Host-symbiont-gene phylogenetic reconciliation by Menet, Hugo, Trung, Alexia Nguyen, Daubin, Vincent, Tannier, Eric

“…We evaluate the capacity of our method on simulated data, notably its capacity to infer horizontal gene transfers, and its ability to detect hostsymbiont co-evolution by comparing host/symbiont/gene and symbiont/gene models based on their estimated likelihoods. …”
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Association between the triglyceride–glucose index and the risk of acute kidney injury in critically ill patients with acute pancreatitis: a retrospective study by Zheng Wang, Haoyu Zhang, Xiaozhou Xie, Jie Li, Yuchen Jia, Jiongdi Lu, Chongchong Gao, Feng Cao, Fei Li

“…Abstract Background The triglyceride–glucose (TyG) index is increasingly recognized for its ability to predict cardiovascular and metabolic risks. …”
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Moving beyond post hoc explainable artificial intelligence: a perspective paper on lessons learned from dynamical climate modeling by R. J. O'Loughlin, D. Li, R. Neale, T. A. O'Brien, T. A. O'Brien

“…We propose three types of understanding as a basis to evaluate trust in dynamical and AI models alike: (1) instrumental understanding, which is obtained when a model has passed a functional test; (2) statistical understanding, obtained when researchers can make sense of the modeling results using statistical techniques to identify input–output relationships; and (3) component-level understanding, which refers to modelers' ability to point to specific model components or parts in the model architecture as the culprit for erratic model behaviors or as the crucial reason why the model functions well. …”
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Risk prediction models for stress urinary incontinence after pelvic organ prolapse (POP) surgery: a systematic review and meta-analysis by Bi Jun Yu, Hao Chong He, Li Wang, Han Mei Shao, Ying Min Liu, Xiao Ying Yan, Jian Liu

“…The pooled AUC value of the validated models was 0.72 (95% CI: 0.65, 0.79), indicating moderate predictive ability. Conclusion The prediction models evaluated demonstrated moderate discrimination, but significant bias and methodological flaws. …”
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Incidence of methicillin, inducible clindamycin, and vancomycin resistance in Staphylococcus aureus clinical isolates in Gombe, Northeastern Nigeria by Haruna Adamu, Celestina T. Otegwu, Fatima B. Abdullahi, Babajide A. Tytler, Busayo O. Olayinka

“…Introduction: Antimicrobial resistance (AMR) has become a significant public health concern, jeopardizing the ability to effectively prevent and treat a growing number of infections caused by microorganisms that no longer respond to standard treatments. …”
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A prospective, cross-sectional study to establish age-specific reference intervals for neonates and children in the setting of clinical biochemistry, immunology and haematology: th... by Susan M Donath, Monsurul Hoq, Vicky Karlaftis, Susan Mathews, Janet Burgess, John Carlin, Paul Monagle, Vera Ignjatovic

“…However, the accuracy of a reference interval is dependent on the selected reference population, and in paediatrics, the ability of the reference interval to reflect changes associated with growth and age, as well as sex and ethnicity. …”
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Cell-free osteoarthritis treatment with dual-engineered chondrocyte-targeted extracellular vesicles derived from mechanical loading primed mesenchymal stem cells by Peng Wang, Haiyue Zhao, Wei Chen, Yuhui Guo, Shuo Zhang, Xin Xing, Shuai Yang, Fengkun Wang, Juan Wang, Zengwu Shao, Yingze Zhang

“…CTP/miR OE -EVs exhibit excellent ability to specifically target cartilage and ameliorate OA pathology. …”
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Bubble connectivity in experimentally-sheared crystal-bearing silicic melts by Daffos, Camille, Martel, Caroline, Arbaret, Laurent, Champallier, Rémi

“…The explosivity of an eruption is mainly controlled by the ability of gases to escape the magma column. Indeed, magmas able to evacuate gases mostly erupt effusively whereas magmas that retain pressurised gases are likely to trigger explosive events. …”
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How far? Travel burdens for children admitted to hospitals in the Western Cape Province of South Africa by M Richards, D le Roux, D Pienaar

“… Background: The ability to access effective hospital care for children is a significant determinant of good health outcomes. …”
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Operation time as a prognostic indicator on postoperative complications following percutaneous nephrolithotomy by Alireza Pakdel, Abdolreza Mohammadi, Amirreza Shamshirgaran, Ehsan Zemanati Yar, Leila Zareian Baghdadabad, Farshid Alaeddini, Roghayeh Koohi Ortakand, Leonardo Oliveira Reis, Seyed Reza Hosseini, Seyed Mohammad Kazem Aghamir

“…Logistic regression models were fitted and the ability of the surgery time to predict complications, major complications, and systemic inflammatory response syndrome was evaluated using receiver-operating characteristic curves. …”
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Bioinspired activation strategies for Peano-HASEL artificial muscle. by Zhaozhen Liu, Harrison McAleese, Andrew Weightman, Glen Cooper

“…<h4>Background</h4>Human muscles perform many functions during activities of daily living producing a wide range of force outputs, displacements, and velocities. This versatile ability is believed to be associated with muscle activation strategies, such as the number and position of activated motor units within the muscle, as well as the frequency, magnitude and shape of the activation signal. …”
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Gut microbial subtypes and clinicopathological value for colorectal cancer by Shuwen Han, Jing Zhuang, Yifei Song, Xinyue Wu, Xiaojian Yu, Ye Tao, Jian Chu, Zhanbo Qu, Yinhang Wu, Shugao Han, Xi Yang

“…Finally, the predictive ability of CatBoost models for CRC identification was improved based on gut microbial subtypes. …”
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Increasing Safety of Vulnerable Road Users in Scenarios With Occlusion: A Collaborative Approach for Smart Infrastructures and Automated Vehicles by Thiago de Borba, Ondrej Vaculin, Hormoz Marzbani, Reza Nakhaie Jazar

“…The occlusion, caused by obstructing the sensors&#x2019; detection field, limits the vehicle&#x2019;s perception ability and inhibits the detection of other road users in the surroundings, especially Vulnerable Road Users (VRUs). …”
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Acute effect of technique modification training on 180° change of direction performance and kinematics in adolescent male soccer players by Hayato Nakamura, Daichi Yamashita, Daichi Nishiumi, Naoto Nakaichi, Norikazu Hirose

“…On the other hand, the COD group showed significant interactions and improvements in average deceleration from final foot (FF) contact to Stop (p = 0.012, g = 0.639), penultimate foot hip flexion angle at Stop (p = 0.042, g = 0.496), COM-FF horizontal distance at Stop (p = 0.008, g = 0.650), and FF ground contact time (p &lt; 0.001, g = 0.803).ConclusionA 15-min COD technique modification training led to partial, immediate improvements in kinematic parameters among adolescent soccer players but did not enhance overall COD performance or acceleration/deceleration ability.…”
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Association of urban green and blue space with accelerated ageing: A cohort Study in the UK Biobank by YiNi Wang, XinYu Shi, Fei Yang, ShengYuan Wang, TianShu Han, Kun Ma

“…Results: After controlling for random effects and various types of covariates, we found that 1) populations with higher levels of UGBS exposure are associated with accelerated ageing and slowing down; 2) UGBS has the greatest impact on accelerated ageing within a 1000-m street network buffer distance; 3) Participants living in heavily polluted areas should pay more attention to UGBS; 4) Intermediary analysis found that UGBS mainly accelerates aging by reducing harm, rather than affecting the population's ability to recover and build. Conclusions: UGBS with a composite weighted score showed a better correlation with accelerated ageing than green spaces. …”
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