Low Concentrations of Monosodium Glutamate (MSG) are Safe in Male Drosophila Melanogaster.

Objective: Monosodium glutamate (MSG) has been marred by a lot of controversy on its safety. In a majority of experimental studies, administration of the compound has been parenteral, and yet little is known about MSG safety consumed as a food supplement. In this study, we assessed the effects of lo...

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Main Authors: Keneth Iceland, Kasozi, Namubiru, Sarah, Kiconco, Oliver, Kinyi, Hellen Wambui, Ssempijja, Fred, Chukwujekwu Ezeonwumelu, Joseph Obiezu, Ninsiima, Herbert Izo, Okpanachi, Alfred Omachonu
Format: Article
Language:en_US
Published: Kabale University 2023
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Online Access:http://hdl.handle.net/20.500.12493/904
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author Keneth Iceland, Kasozi
Namubiru, Sarah
Kiconco, Oliver
Kinyi, Hellen Wambui
Ssempijja, Fred
Chukwujekwu Ezeonwumelu, Joseph Obiezu
Ninsiima, Herbert Izo
Okpanachi, Alfred Omachonu
author_facet Keneth Iceland, Kasozi
Namubiru, Sarah
Kiconco, Oliver
Kinyi, Hellen Wambui
Ssempijja, Fred
Chukwujekwu Ezeonwumelu, Joseph Obiezu
Ninsiima, Herbert Izo
Okpanachi, Alfred Omachonu
author_sort Keneth Iceland, Kasozi
collection KAB-DR
description Objective: Monosodium glutamate (MSG) has been marred by a lot of controversy on its safety. In a majority of experimental studies, administration of the compound has been parenteral, and yet little is known about MSG safety consumed as a food supplement. In this study, we assessed the effects of low concentrations of MSG on the activity of hydrogen scavenging, catalase activity and climbing as well as lifespan in male Drosophila melanogaster over a 30 days period since this has been sparsely studied. Results: No significant differences were associated with MSG at 5%, 1%, 0.2%, 0.04% on hydrogen peroxide scavenging,negative geotaxis and lifespan in W1118 male D. melanogaster. Significant differences were found in 5% MSG on catalase activity, showing that high MSG concentrations would affect tissue health in male D. melanogaster. MSG consumed as a food supplement would be safe at concentrations below 5% MSG. Keywords: Drosophila Melanogaster, MSG Safety, MSG Toxicity, Catalase Activity.
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publisher Kabale University
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spelling oai:idr.kab.ac.ug:20.500.12493-9042024-01-17T04:44:45Z Low Concentrations of Monosodium Glutamate (MSG) are Safe in Male Drosophila Melanogaster. Keneth Iceland, Kasozi Namubiru, Sarah Kiconco, Oliver Kinyi, Hellen Wambui Ssempijja, Fred Chukwujekwu Ezeonwumelu, Joseph Obiezu Ninsiima, Herbert Izo Okpanachi, Alfred Omachonu Drosophila Melanogaster MSG Safety MSG Toxicity Catalase Activity Objective: Monosodium glutamate (MSG) has been marred by a lot of controversy on its safety. In a majority of experimental studies, administration of the compound has been parenteral, and yet little is known about MSG safety consumed as a food supplement. In this study, we assessed the effects of low concentrations of MSG on the activity of hydrogen scavenging, catalase activity and climbing as well as lifespan in male Drosophila melanogaster over a 30 days period since this has been sparsely studied. Results: No significant differences were associated with MSG at 5%, 1%, 0.2%, 0.04% on hydrogen peroxide scavenging,negative geotaxis and lifespan in W1118 male D. melanogaster. Significant differences were found in 5% MSG on catalase activity, showing that high MSG concentrations would affect tissue health in male D. melanogaster. MSG consumed as a food supplement would be safe at concentrations below 5% MSG. Keywords: Drosophila Melanogaster, MSG Safety, MSG Toxicity, Catalase Activity. 2023-01-31T11:48:58Z 2023-01-31T11:48:58Z 2018 Article http://hdl.handle.net/20.500.12493/904 en_US application/pdf Kabale University
spellingShingle Drosophila Melanogaster
MSG Safety
MSG Toxicity
Catalase Activity
Keneth Iceland, Kasozi
Namubiru, Sarah
Kiconco, Oliver
Kinyi, Hellen Wambui
Ssempijja, Fred
Chukwujekwu Ezeonwumelu, Joseph Obiezu
Ninsiima, Herbert Izo
Okpanachi, Alfred Omachonu
Low Concentrations of Monosodium Glutamate (MSG) are Safe in Male Drosophila Melanogaster.
title Low Concentrations of Monosodium Glutamate (MSG) are Safe in Male Drosophila Melanogaster.
title_full Low Concentrations of Monosodium Glutamate (MSG) are Safe in Male Drosophila Melanogaster.
title_fullStr Low Concentrations of Monosodium Glutamate (MSG) are Safe in Male Drosophila Melanogaster.
title_full_unstemmed Low Concentrations of Monosodium Glutamate (MSG) are Safe in Male Drosophila Melanogaster.
title_short Low Concentrations of Monosodium Glutamate (MSG) are Safe in Male Drosophila Melanogaster.
title_sort low concentrations of monosodium glutamate msg are safe in male drosophila melanogaster
topic Drosophila Melanogaster
MSG Safety
MSG Toxicity
Catalase Activity
url http://hdl.handle.net/20.500.12493/904
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