Molecular epidemiology of anaplasmosis in small ruminants along a human-livestock-wildlife interface in Uganda
Background: Information as regards the epidemiology of the Anaplasmataceae in small ruminants in several lowand middle-income countries is scarce. Methods: In this study a total of 712 DNA samples collected from small ruminants were analyzed for Anaplasmataceae and Anaplasma ovis using the 16S rR...
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2021
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| Online Access: | http://hdl.handle.net/20.500.12493/520 |
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| author | Keneth Iceland, Kasozi Susan Christina, Welburn |
| author_facet | Keneth Iceland, Kasozi Susan Christina, Welburn |
| author_sort | Keneth Iceland, Kasozi |
| collection | KAB-DR |
| description | Background: Information as regards the epidemiology of the Anaplasmataceae in small ruminants in several lowand
middle-income countries is scarce.
Methods: In this study a total of 712 DNA samples collected from small ruminants were analyzed for Anaplasmataceae
and Anaplasma ovis using the 16S rRNA and MSP4 genes respectively. Infection risk was assessed by
location, sex and age of the animals and qGIS® was used to construct spatial maps.
Results: The prevalence of Anaplasmataceae spp was 89.1% (95% CI: 77.5–95.9) and 79.1% (95% CI: 75.9–82.1) in
ovines and caprines respectively (RR ¼ 1.1, 95% CI: 1.0–1.3); higher than those previously reported in other
eastern African countries. The prevalence of A. ovis was 26.1% and 25.4% for both ovines and caprines respectively
with ovines showing significantly higher levels of infection than caprines (P < 0.05). The risk of Anaplasma
ovis infections was not affected by age (OR ¼ 1.2, 95% CI: 0.9–1.7) or sex (OR ¼ 1.1, 95% CI: 0.6–2.0). Small
ruminants located at the forest edge (<0.3 km) showed higher A. ovis prevalence than those found inland with
infections present in the midland regions associated with increased agricultural activity.
Conclusion: Anaplasma ovis remains a major challenge for small ruminant husbandry in Uganda and infections are
under-reported. Policy efforts to prioritize management of Anaplasmataceae for small ruminant health would
promote livestock productivity in vulnerable communities, improving livelihoods and ecosystem health. |
| format | Article |
| id | oai:idr.kab.ac.ug:20.500.12493-520 |
| institution | KAB-DR |
| publishDate | 2021 |
| publisher | Heliyon |
| record_format | dspace |
| spelling | oai:idr.kab.ac.ug:20.500.12493-5202024-01-17T04:50:00Z Molecular epidemiology of anaplasmosis in small ruminants along a human-livestock-wildlife interface in Uganda Keneth Iceland, Kasozi Susan Christina, Welburn Tick-borne diseases Anaplasma ovis Parasites Small ruminants Goats Uganda Africa Ticks Tick resistance Tick vaccines Entomology Ecosystem services Protozoa Polymerase chain reaction Epidemiology Veterinary medicine Animal behavior Animal breeding Ruminant Agriculture Background: Information as regards the epidemiology of the Anaplasmataceae in small ruminants in several lowand middle-income countries is scarce. Methods: In this study a total of 712 DNA samples collected from small ruminants were analyzed for Anaplasmataceae and Anaplasma ovis using the 16S rRNA and MSP4 genes respectively. Infection risk was assessed by location, sex and age of the animals and qGIS® was used to construct spatial maps. Results: The prevalence of Anaplasmataceae spp was 89.1% (95% CI: 77.5–95.9) and 79.1% (95% CI: 75.9–82.1) in ovines and caprines respectively (RR ¼ 1.1, 95% CI: 1.0–1.3); higher than those previously reported in other eastern African countries. The prevalence of A. ovis was 26.1% and 25.4% for both ovines and caprines respectively with ovines showing significantly higher levels of infection than caprines (P < 0.05). The risk of Anaplasma ovis infections was not affected by age (OR ¼ 1.2, 95% CI: 0.9–1.7) or sex (OR ¼ 1.1, 95% CI: 0.6–2.0). Small ruminants located at the forest edge (<0.3 km) showed higher A. ovis prevalence than those found inland with infections present in the midland regions associated with increased agricultural activity. Conclusion: Anaplasma ovis remains a major challenge for small ruminant husbandry in Uganda and infections are under-reported. Policy efforts to prioritize management of Anaplasmataceae for small ruminant health would promote livestock productivity in vulnerable communities, improving livelihoods and ecosystem health. Kabale University 2021-07-30T18:50:00Z 2021-07-30T18:50:00Z 2020 Article http://hdl.handle.net/20.500.12493/520 application/pdf Heliyon |
| spellingShingle | Tick-borne diseases Anaplasma ovis Parasites Small ruminants Goats Uganda Africa Ticks Tick resistance Tick vaccines Entomology Ecosystem services Protozoa Polymerase chain reaction Epidemiology Veterinary medicine Animal behavior Animal breeding Ruminant Agriculture Keneth Iceland, Kasozi Susan Christina, Welburn Molecular epidemiology of anaplasmosis in small ruminants along a human-livestock-wildlife interface in Uganda |
| title | Molecular epidemiology of anaplasmosis in small ruminants along a human-livestock-wildlife interface in Uganda |
| title_full | Molecular epidemiology of anaplasmosis in small ruminants along a human-livestock-wildlife interface in Uganda |
| title_fullStr | Molecular epidemiology of anaplasmosis in small ruminants along a human-livestock-wildlife interface in Uganda |
| title_full_unstemmed | Molecular epidemiology of anaplasmosis in small ruminants along a human-livestock-wildlife interface in Uganda |
| title_short | Molecular epidemiology of anaplasmosis in small ruminants along a human-livestock-wildlife interface in Uganda |
| title_sort | molecular epidemiology of anaplasmosis in small ruminants along a human livestock wildlife interface in uganda |
| topic | Tick-borne diseases Anaplasma ovis Parasites Small ruminants Goats Uganda Africa Ticks Tick resistance Tick vaccines Entomology Ecosystem services Protozoa Polymerase chain reaction Epidemiology Veterinary medicine Animal behavior Animal breeding Ruminant Agriculture |
| url | http://hdl.handle.net/20.500.12493/520 |
| work_keys_str_mv | AT kenethicelandkasozi molecularepidemiologyofanaplasmosisinsmallruminantsalongahumanlivestockwildlifeinterfaceinuganda AT susanchristinawelburn molecularepidemiologyofanaplasmosisinsmallruminantsalongahumanlivestockwildlifeinterfaceinuganda |