Sociodemographic factors associated with acceptance of COVID-19 vaccine and clinical trials in Uganda: a cross-sectional study in western Uganda

Background: Health experts agree that widespread use of safe and effective vaccines will rapidly contain the COVID-19 pandemic. The big question is whether these vaccines can easily be accepted by their end-users. Our study aimed at determining sociodemographic factors associated with acceptance o...

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Main Authors: Isaac, Echoru, Patricia, Decanar Ajambo, Emmanuel, Keirania, Edmund E. M, Bukenya
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Published: BMC Public Health 2021
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Online Access:http://hdl.handle.net/20.500.12493/517
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author Isaac, Echoru
Patricia, Decanar Ajambo
Emmanuel, Keirania
Edmund E. M, Bukenya
author_facet Isaac, Echoru
Patricia, Decanar Ajambo
Emmanuel, Keirania
Edmund E. M, Bukenya
author_sort Isaac, Echoru
collection KAB-DR
description Background: Health experts agree that widespread use of safe and effective vaccines will rapidly contain the COVID-19 pandemic. The big question is whether these vaccines can easily be accepted by their end-users. Our study aimed at determining sociodemographic factors associated with acceptance of vaccines and clinical trials of COVID-19 in western Uganda. Method: A simplified snowball sampling technique was used to select 1067 respondents of 18–70 years in western Uganda using an online questionnaire from July to September 2020. Vaccine acceptability and risk perception were assessed using odds ratio at 95% confidence interval in R software version 3.6.3. Results: There were 1067 participants in the study. The majority were males (73.2%) and age group 31– 40 years (32.6%). The acceptance rate for COVID-19 vaccination was (53.6%; 572/1067) with those aged 18–20 years, males, elites at tertiary level of education (degree or diploma), students, Muslims, married, non-salary earners and rural dwellers having better odds and likeliness to accept vaccination. Only 44.6% (476/1067) showed interest in clinical trials among which; males, primary school leavers, students, Christians, un-married, respondents who didn’t earn any salary and rural dwellers had better odds and likelihood to participate in clinical trials. Conclusion: There was a low level of vaccine acceptance and clinical trial interest in western Uganda. Minority groups in the study i.e., Muslims, students, primary school leavers, un-married rural dwellers among others showed more interest in vaccination and clinical trials. We anticipated fears in the larger part of this community that health experts need to address through reassurance of the community that vaccines are tested and that they are safe and important if we are to rapidly contain the COVID-19 pandemic.
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spelling oai:idr.kab.ac.ug:20.500.12493-5172024-01-17T04:45:27Z Sociodemographic factors associated with acceptance of COVID-19 vaccine and clinical trials in Uganda: a cross-sectional study in western Uganda Isaac, Echoru Patricia, Decanar Ajambo Emmanuel, Keirania Edmund E. M, Bukenya COVID-19, vaccine, Acceptance, Clinical trials, Western Uganda Background: Health experts agree that widespread use of safe and effective vaccines will rapidly contain the COVID-19 pandemic. The big question is whether these vaccines can easily be accepted by their end-users. Our study aimed at determining sociodemographic factors associated with acceptance of vaccines and clinical trials of COVID-19 in western Uganda. Method: A simplified snowball sampling technique was used to select 1067 respondents of 18–70 years in western Uganda using an online questionnaire from July to September 2020. Vaccine acceptability and risk perception were assessed using odds ratio at 95% confidence interval in R software version 3.6.3. Results: There were 1067 participants in the study. The majority were males (73.2%) and age group 31– 40 years (32.6%). The acceptance rate for COVID-19 vaccination was (53.6%; 572/1067) with those aged 18–20 years, males, elites at tertiary level of education (degree or diploma), students, Muslims, married, non-salary earners and rural dwellers having better odds and likeliness to accept vaccination. Only 44.6% (476/1067) showed interest in clinical trials among which; males, primary school leavers, students, Christians, un-married, respondents who didn’t earn any salary and rural dwellers had better odds and likelihood to participate in clinical trials. Conclusion: There was a low level of vaccine acceptance and clinical trial interest in western Uganda. Minority groups in the study i.e., Muslims, students, primary school leavers, un-married rural dwellers among others showed more interest in vaccination and clinical trials. We anticipated fears in the larger part of this community that health experts need to address through reassurance of the community that vaccines are tested and that they are safe and important if we are to rapidly contain the COVID-19 pandemic. Kabale University 2021-07-30T18:26:13Z 2021-07-30T18:26:13Z 2021 Article https://doi.org/10.1186/s12889-021-11197-7 http://hdl.handle.net/20.500.12493/517 application/pdf BMC Public Health
spellingShingle COVID-19, vaccine, Acceptance, Clinical trials, Western Uganda
Isaac, Echoru
Patricia, Decanar Ajambo
Emmanuel, Keirania
Edmund E. M, Bukenya
Sociodemographic factors associated with acceptance of COVID-19 vaccine and clinical trials in Uganda: a cross-sectional study in western Uganda
title Sociodemographic factors associated with acceptance of COVID-19 vaccine and clinical trials in Uganda: a cross-sectional study in western Uganda
title_full Sociodemographic factors associated with acceptance of COVID-19 vaccine and clinical trials in Uganda: a cross-sectional study in western Uganda
title_fullStr Sociodemographic factors associated with acceptance of COVID-19 vaccine and clinical trials in Uganda: a cross-sectional study in western Uganda
title_full_unstemmed Sociodemographic factors associated with acceptance of COVID-19 vaccine and clinical trials in Uganda: a cross-sectional study in western Uganda
title_short Sociodemographic factors associated with acceptance of COVID-19 vaccine and clinical trials in Uganda: a cross-sectional study in western Uganda
title_sort sociodemographic factors associated with acceptance of covid 19 vaccine and clinical trials in uganda a cross sectional study in western uganda
topic COVID-19, vaccine, Acceptance, Clinical trials, Western Uganda
url http://hdl.handle.net/20.500.12493/517
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AT emmanuelkeirania sociodemographicfactorsassociatedwithacceptanceofcovid19vaccineandclinicaltrialsinugandaacrosssectionalstudyinwesternuganda
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