Lycopene improves on basic hematological and immunological parameters in diabetes mellitus
Objective: Diabetes is associated with an upset of hematological and immunological parameters in humans, however information on the effects of Lycopene is scarce. The aim of the study was to gain information on basic changes in hematological parameters as markers for safety since anemia as a compl...
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| Format: | Article |
| Language: | en_US |
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BMC
2020
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| Online Access: | http://hdl.handle.net/20.500.12493/437 |
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| _version_ | 1800403075432710144 |
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| author | Ejike, Daniel Eze Adam Moyosore, Afodun Josephine, Kasolo Keneth Iceland, Kasozi |
| author_facet | Ejike, Daniel Eze Adam Moyosore, Afodun Josephine, Kasolo Keneth Iceland, Kasozi |
| author_sort | Ejike, Daniel Eze |
| collection | KAB-DR |
| description | Objective: Diabetes is associated with an upset of hematological and immunological parameters in humans, however
information on the effects of Lycopene is scarce. The aim of the study was to gain information on basic changes
in hematological parameters as markers for safety since anemia as a complication in diabetic chemotherapy has been
reported.
Results: Lycopene had anti-anemic effects and improved on the immune status of diabetic rats and these observations
were dose independent. There was a decrease in neutrophil, low neutrophil–lymphocyte ratio and platelet
counts and stable albumin, globulin levels. Lycopene could exert its protective effects through a balance of basic
hematological physiological variables. |
| format | Article |
| id | oai:idr.kab.ac.ug:20.500.12493-437 |
| institution | KAB-DR |
| language | en_US |
| publishDate | 2020 |
| publisher | BMC |
| record_format | dspace |
| spelling | oai:idr.kab.ac.ug:20.500.12493-4372024-01-17T04:46:33Z Lycopene improves on basic hematological and immunological parameters in diabetes mellitus Ejike, Daniel Eze Adam Moyosore, Afodun Josephine, Kasolo Keneth Iceland, Kasozi Antioxidants, Diabetes, Anemia, Carotenoids, Blood Objective: Diabetes is associated with an upset of hematological and immunological parameters in humans, however information on the effects of Lycopene is scarce. The aim of the study was to gain information on basic changes in hematological parameters as markers for safety since anemia as a complication in diabetic chemotherapy has been reported. Results: Lycopene had anti-anemic effects and improved on the immune status of diabetic rats and these observations were dose independent. There was a decrease in neutrophil, low neutrophil–lymphocyte ratio and platelet counts and stable albumin, globulin levels. Lycopene could exert its protective effects through a balance of basic hematological physiological variables. Kabale University 2020-07-09T07:52:49Z 2020-07-09T07:52:49Z 2019 Article https://doi.org/10.1186/s13104-019-4841-8 http://hdl.handle.net/20.500.12493/437 en_US application/pdf BMC |
| spellingShingle | Antioxidants, Diabetes, Anemia, Carotenoids, Blood Ejike, Daniel Eze Adam Moyosore, Afodun Josephine, Kasolo Keneth Iceland, Kasozi Lycopene improves on basic hematological and immunological parameters in diabetes mellitus |
| title | Lycopene improves on basic hematological and immunological parameters in diabetes mellitus |
| title_full | Lycopene improves on basic hematological and immunological parameters in diabetes mellitus |
| title_fullStr | Lycopene improves on basic hematological and immunological parameters in diabetes mellitus |
| title_full_unstemmed | Lycopene improves on basic hematological and immunological parameters in diabetes mellitus |
| title_short | Lycopene improves on basic hematological and immunological parameters in diabetes mellitus |
| title_sort | lycopene improves on basic hematological and immunological parameters in diabetes mellitus |
| topic | Antioxidants, Diabetes, Anemia, Carotenoids, Blood |
| url | http://hdl.handle.net/20.500.12493/437 |
| work_keys_str_mv | AT ejikedanieleze lycopeneimprovesonbasichematologicalandimmunologicalparametersindiabetesmellitus AT adammoyosoreafodun lycopeneimprovesonbasichematologicalandimmunologicalparametersindiabetesmellitus AT josephinekasolo lycopeneimprovesonbasichematologicalandimmunologicalparametersindiabetesmellitus AT kenethicelandkasozi lycopeneimprovesonbasichematologicalandimmunologicalparametersindiabetesmellitus |