Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster

Objective: The purpose of the study was to generate information on the safety of probiotics, thus the study objectives were to evaluate the effects of Yoba ® on basic physiochemical properties. The study assessed male w1118 Drosophila melanogaster which were provided food supplemented with Yoba ®...

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Main Authors: Keneth Iceland, Kasozi, Aisha, Bukenya, Ejike, Daniel Eze, Josephine, Kasolo, Dickson Stuart, Tayebwa, Fred, Ssempijja, Joy, Suubo, Andrew, Tamale, Isaac, Echoru, Ibrahim, Ntulume, Sarah Kemuma, Onkoba, Lisa Nkatha, Micheni, Emmanuel Tiyo, Ayikobua, Oscar Hilary, Asiimwe, Muhamudu, Kalange
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Language:en_US
Published: Research Note 2020
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Online Access:http://hdl.handle.net/20.500.12493/426
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author Keneth Iceland, Kasozi
Aisha, Bukenya
Ejike, Daniel Eze
Josephine, Kasolo
Dickson Stuart, Tayebwa
Fred, Ssempijja
Joy, Suubo
Andrew, Tamale
Isaac, Echoru
Ibrahim, Ntulume
Sarah Kemuma, Onkoba
Lisa Nkatha, Micheni
Emmanuel Tiyo, Ayikobua
Oscar Hilary, Asiimwe
Muhamudu, Kalange
author_facet Keneth Iceland, Kasozi
Aisha, Bukenya
Ejike, Daniel Eze
Josephine, Kasolo
Dickson Stuart, Tayebwa
Fred, Ssempijja
Joy, Suubo
Andrew, Tamale
Isaac, Echoru
Ibrahim, Ntulume
Sarah Kemuma, Onkoba
Lisa Nkatha, Micheni
Emmanuel Tiyo, Ayikobua
Oscar Hilary, Asiimwe
Muhamudu, Kalange
author_sort Keneth Iceland, Kasozi
collection KAB-DR
description Objective: The purpose of the study was to generate information on the safety of probiotics, thus the study objectives were to evaluate the effects of Yoba ® on basic physiochemical properties. The study assessed male w1118 Drosophila melanogaster which were provided food supplemented with Yoba ® at 1%, 3%, 6%, and 12% on motor function, total protein, catalase activity, and hydrogen peroxide scavenging activity and lifespan. Results: Yoba® at high concentration (≥ 6%) increased locomotor activity in Drosophila melanogaster, however, total protein, catalase, and hydrogen peroxide scavenging activity were significantly higher at 1% Yoba ® compared to 3%, 6%, and 12% Yoba ®. Yoba consumed at 1% was associated with greater physiological benefits in Drosophila melanogaster. Findings in the study offer a rationale for the consumption of Yoba ® at 1% in humans as is currently being promoted by the Yoba for Life consortium, however, high concentrations of Yoba ® would disrupt physiological function as shown by this study.
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spelling oai:idr.kab.ac.ug:20.500.12493-4262024-01-17T04:43:48Z Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster Keneth Iceland, Kasozi Aisha, Bukenya Ejike, Daniel Eze Josephine, Kasolo Dickson Stuart, Tayebwa Fred, Ssempijja Joy, Suubo Andrew, Tamale Isaac, Echoru Ibrahim, Ntulume Sarah Kemuma, Onkoba Lisa Nkatha, Micheni Emmanuel Tiyo, Ayikobua Oscar Hilary, Asiimwe Muhamudu, Kalange Probiotics, Yoba for life, Nutritional toxicology, Yoghurt, Food supplements, Catalase, Hydrogen peroxide scavenging, Aging Objective: The purpose of the study was to generate information on the safety of probiotics, thus the study objectives were to evaluate the effects of Yoba ® on basic physiochemical properties. The study assessed male w1118 Drosophila melanogaster which were provided food supplemented with Yoba ® at 1%, 3%, 6%, and 12% on motor function, total protein, catalase activity, and hydrogen peroxide scavenging activity and lifespan. Results: Yoba® at high concentration (≥ 6%) increased locomotor activity in Drosophila melanogaster, however, total protein, catalase, and hydrogen peroxide scavenging activity were significantly higher at 1% Yoba ® compared to 3%, 6%, and 12% Yoba ®. Yoba consumed at 1% was associated with greater physiological benefits in Drosophila melanogaster. Findings in the study offer a rationale for the consumption of Yoba ® at 1% in humans as is currently being promoted by the Yoba for Life consortium, however, high concentrations of Yoba ® would disrupt physiological function as shown by this study. Kabale University 2020-07-06T09:30:36Z 2020-07-06T09:30:36Z 2019 Article http://hdl.handle.net/20.500.12493/426 en_US application/pdf Research Note
spellingShingle Probiotics, Yoba for life, Nutritional toxicology, Yoghurt, Food supplements, Catalase, Hydrogen peroxide scavenging, Aging
Keneth Iceland, Kasozi
Aisha, Bukenya
Ejike, Daniel Eze
Josephine, Kasolo
Dickson Stuart, Tayebwa
Fred, Ssempijja
Joy, Suubo
Andrew, Tamale
Isaac, Echoru
Ibrahim, Ntulume
Sarah Kemuma, Onkoba
Lisa Nkatha, Micheni
Emmanuel Tiyo, Ayikobua
Oscar Hilary, Asiimwe
Muhamudu, Kalange
Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster
title Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster
title_full Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster
title_fullStr Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster
title_full_unstemmed Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster
title_short Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster
title_sort low concentrations of lactobacillus rhamnosus gg yoba r are safe in male drosophila melanogaster
topic Probiotics, Yoba for life, Nutritional toxicology, Yoghurt, Food supplements, Catalase, Hydrogen peroxide scavenging, Aging
url http://hdl.handle.net/20.500.12493/426
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