Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster
Objective: The purpose of the study was to generate information on the safety of probiotics, thus the study objectives were to evaluate the effects of Yoba ® on basic physiochemical properties. The study assessed male w1118 Drosophila melanogaster which were provided food supplemented with Yoba ®...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | en_US |
| Published: |
Research Note
2020
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.12493/426 |
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| Summary: | Objective: The purpose of the study was to generate information on the safety of probiotics, thus the study objectives
were to evaluate the effects of Yoba ® on basic physiochemical properties. The study assessed male w1118 Drosophila
melanogaster which were provided food supplemented with Yoba ® at 1%, 3%, 6%, and 12% on motor function,
total protein, catalase activity, and hydrogen peroxide scavenging activity and lifespan.
Results: Yoba® at high concentration (≥ 6%) increased locomotor activity in Drosophila melanogaster, however, total
protein, catalase, and hydrogen peroxide scavenging activity were significantly higher at 1% Yoba
® compared to 3%, 6%, and 12% Yoba ®. Yoba consumed at 1% was associated with greater physiological benefits in Drosophila melanogaster.
Findings in the study offer a rationale for the consumption of Yoba ® at 1% in humans as is currently being
promoted by the Yoba for Life consortium, however, high concentrations of Yoba ® would disrupt physiological function
as shown by this study. |
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