Flavonoids and Isoflavonoids of Millettia dura and Millettia ferruginea: Phytochemical review and chemotaxonomic values

The phytochemical information on Millettia dura Dunn, M. ferruginea (Hochst.) Baker and M. ferruginea subsp. darassana (Cufod.) J.B. Gillett was reviewed. All the three taxa elaborate mainly isoflavones (33 reported), occurring in the flowers, seeds/seed pods, stem bark and root bark. Out of the 33...

Full description

Saved in:
Bibliographic Details
Main Authors: Buyinza, Daniel, Chalo, Duncan Mutiso, Derese, Solomon, Ndakala, Albert, Yenesew, Abiy
Format: Article
Language:English
Published: Elsevier 2025
Subjects:
Online Access:http://hdl.handle.net/20.500.12493/2935
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1856816791273078784
author Buyinza, Daniel
Chalo, Duncan Mutiso
Derese, Solomon
Ndakala, Albert
Yenesew, Abiy
author_facet Buyinza, Daniel
Chalo, Duncan Mutiso
Derese, Solomon
Ndakala, Albert
Yenesew, Abiy
author_sort Buyinza, Daniel
collection KAB-DR
description The phytochemical information on Millettia dura Dunn, M. ferruginea (Hochst.) Baker and M. ferruginea subsp. darassana (Cufod.) J.B. Gillett was reviewed. All the three taxa elaborate mainly isoflavones (33 reported), occurring in the flowers, seeds/seed pods, stem bark and root bark. Out of the 33 isoflavones reported, some 19 (ca. 58%) contain prenyl at C-8 or its modification as 2,2-dimethylchromene ring at C-7/C-8, occurring in all the three taxa. Except for three isoflavones isolated from M. ferruginea subsp. darassana, all the isoflavones of these taxa are 5-deoxygenated. In these taxa, oxygenation at C-6 is a common feature, while isoflavones with C-8 oxygenation are rare, only three reported, and all of these from M. dura. There are 7 rotenoids reported from these taxa, and occur almost entirely in the seeds/seedpods of these plants. The major rotenoid with methyle nedioxy group at C-2/C-3, millettone and its 12a-hydroxy derivative, millettosine, occur only in M. dura, this appears to distinguish M. dura from M. ferruginea.
format Article
id oai:idr.kab.ac.ug:20.500.12493-2935
institution KAB-DR
language English
publishDate 2025
publisher Elsevier
record_format dspace
spelling oai:idr.kab.ac.ug:20.500.12493-29352025-09-03T00:00:33Z Flavonoids and Isoflavonoids of Millettia dura and Millettia ferruginea: Phytochemical review and chemotaxonomic values Buyinza, Daniel Chalo, Duncan Mutiso Derese, Solomon Ndakala, Albert Yenesew, Abiy Millettia dura Millettia ferruginea Leguminosae Isoflavone Rotenoid Chemotaxonomy The phytochemical information on Millettia dura Dunn, M. ferruginea (Hochst.) Baker and M. ferruginea subsp. darassana (Cufod.) J.B. Gillett was reviewed. All the three taxa elaborate mainly isoflavones (33 reported), occurring in the flowers, seeds/seed pods, stem bark and root bark. Out of the 33 isoflavones reported, some 19 (ca. 58%) contain prenyl at C-8 or its modification as 2,2-dimethylchromene ring at C-7/C-8, occurring in all the three taxa. Except for three isoflavones isolated from M. ferruginea subsp. darassana, all the isoflavones of these taxa are 5-deoxygenated. In these taxa, oxygenation at C-6 is a common feature, while isoflavones with C-8 oxygenation are rare, only three reported, and all of these from M. dura. There are 7 rotenoids reported from these taxa, and occur almost entirely in the seeds/seedpods of these plants. The major rotenoid with methyle nedioxy group at C-2/C-3, millettone and its 12a-hydroxy derivative, millettosine, occur only in M. dura, this appears to distinguish M. dura from M. ferruginea. 2025-09-02T16:45:50Z 2025-09-02T16:45:50Z 2020 Article Buyinza, D., Chalo, D. M., Derese, S., Ndakala, A., & Yenesew, A. (2020). Flavonoids and Isoflavonoids of Millettia dura and Millettia ferruginea: Phytochemical review and chemotaxonomic values. Biochemical Systematics and Ecology, 91, 104053. https://doi.org/10.1016/j.bse.2020.104053 http://hdl.handle.net/20.500.12493/2935 en Attribution-NonCommercial-NoDerivs 3.0 United States http://creativecommons.org/licenses/by-nc-nd/3.0/us/ application/pdf Elsevier
spellingShingle Millettia dura
Millettia ferruginea
Leguminosae
Isoflavone
Rotenoid
Chemotaxonomy
Buyinza, Daniel
Chalo, Duncan Mutiso
Derese, Solomon
Ndakala, Albert
Yenesew, Abiy
Flavonoids and Isoflavonoids of Millettia dura and Millettia ferruginea: Phytochemical review and chemotaxonomic values
title Flavonoids and Isoflavonoids of Millettia dura and Millettia ferruginea: Phytochemical review and chemotaxonomic values
title_full Flavonoids and Isoflavonoids of Millettia dura and Millettia ferruginea: Phytochemical review and chemotaxonomic values
title_fullStr Flavonoids and Isoflavonoids of Millettia dura and Millettia ferruginea: Phytochemical review and chemotaxonomic values
title_full_unstemmed Flavonoids and Isoflavonoids of Millettia dura and Millettia ferruginea: Phytochemical review and chemotaxonomic values
title_short Flavonoids and Isoflavonoids of Millettia dura and Millettia ferruginea: Phytochemical review and chemotaxonomic values
title_sort flavonoids and isoflavonoids of millettia dura and millettia ferruginea phytochemical review and chemotaxonomic values
topic Millettia dura
Millettia ferruginea
Leguminosae
Isoflavone
Rotenoid
Chemotaxonomy
url http://hdl.handle.net/20.500.12493/2935
work_keys_str_mv AT buyinzadaniel flavonoidsandisoflavonoidsofmillettiaduraandmillettiaferrugineaphytochemicalreviewandchemotaxonomicvalues
AT chaloduncanmutiso flavonoidsandisoflavonoidsofmillettiaduraandmillettiaferrugineaphytochemicalreviewandchemotaxonomicvalues
AT deresesolomon flavonoidsandisoflavonoidsofmillettiaduraandmillettiaferrugineaphytochemicalreviewandchemotaxonomicvalues
AT ndakalaalbert flavonoidsandisoflavonoidsofmillettiaduraandmillettiaferrugineaphytochemicalreviewandchemotaxonomicvalues
AT yenesewabiy flavonoidsandisoflavonoidsofmillettiaduraandmillettiaferrugineaphytochemicalreviewandchemotaxonomicvalues