Fighting the next pandemic: A phytochemical Approach from African flora - An overview

Management of any pandemic requires a multidimensional approach with a hand from all players. At every break of a pandemic, there is always no immediate treatment and efforts are often devoted to social distancing, isolation/quarantine, diagnosis, and care with prospects to treat but with no clear m...

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Main Authors: Buyinza, Daniel, Gumula, Ivan
Format: Book chapter
Language:English
Published: Society for the Advancement of Scienvce in Africa 2025
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Online Access:http://hdl.handle.net/20.500.12493/2933
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author Buyinza, Daniel
Gumula, Ivan
author_facet Buyinza, Daniel
Gumula, Ivan
author_sort Buyinza, Daniel
collection KAB-DR
description Management of any pandemic requires a multidimensional approach with a hand from all players. At every break of a pandemic, there is always no immediate treatment and efforts are often devoted to social distancing, isolation/quarantine, diagnosis, and care with prospects to treat but with no clear medication. The approach has always been to permit the body to fight off the pandemic by boosting its immune system through selective diet and or food supplements as external immune boosters in addition to arresting symptoms. With the exception of COVID-19, the burden of HIV epidemic and seasonal flu pandemics, infectious disease outbreaks have mostly devastated developing societies. The use of herbal remedies to cure several kinds of human diseases has a long history in Africa. Various plant parts are used to prevent, dispel symptoms or regress deformities to normal. A portion of the pharmaceutical products currently being prescribed by physicians including opium, aspirin, digitalis, paclitaxel, docetaxel, vinblastine, vincristine, quinine, and artemisinin have a historic use as herbal remedies. African medicinal plants are rich in such natural bioactive metabolites with therapeutic values against several diseases including deadly fevers. The therapeutic properties of these metabolites are a factor of the type and amount of alkaloids, phenolics, flavonoids, quinones, saponins, and terpenes contained. Human ingestion of these bioactive trigger pharmacological effects like antiviral, anti-inflammatory, analgesic, antidiabetic, antimicrobial, anti-parasitic, and antioxidant effects, thereby arresting the causal or symptomatic effects manifested in the pandemics. Ethnomedical and phytochemical studies on the African medicinal plants have led to the isolation of promising antiviral, anti-inflammatory, anti-parasitic, analgesic, and antimicrobial metabolites. Our discussion in this chapter is premised on challenging Africans Scientists (ethnobotanists, phytochemists, microbiologists, and pharmacologists) to collaboratively intensify the search for phytochemicals as drug leads and explore options for developing these leads into functional medicines for the various diseases/pandemics devastating the continent.
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spelling oai:idr.kab.ac.ug:20.500.12493-29332025-09-03T00:00:20Z Fighting the next pandemic: A phytochemical Approach from African flora - An overview Buyinza, Daniel Gumula, Ivan Pandemic herbal remedies phytochemicals drugs. Management of any pandemic requires a multidimensional approach with a hand from all players. At every break of a pandemic, there is always no immediate treatment and efforts are often devoted to social distancing, isolation/quarantine, diagnosis, and care with prospects to treat but with no clear medication. The approach has always been to permit the body to fight off the pandemic by boosting its immune system through selective diet and or food supplements as external immune boosters in addition to arresting symptoms. With the exception of COVID-19, the burden of HIV epidemic and seasonal flu pandemics, infectious disease outbreaks have mostly devastated developing societies. The use of herbal remedies to cure several kinds of human diseases has a long history in Africa. Various plant parts are used to prevent, dispel symptoms or regress deformities to normal. A portion of the pharmaceutical products currently being prescribed by physicians including opium, aspirin, digitalis, paclitaxel, docetaxel, vinblastine, vincristine, quinine, and artemisinin have a historic use as herbal remedies. African medicinal plants are rich in such natural bioactive metabolites with therapeutic values against several diseases including deadly fevers. The therapeutic properties of these metabolites are a factor of the type and amount of alkaloids, phenolics, flavonoids, quinones, saponins, and terpenes contained. Human ingestion of these bioactive trigger pharmacological effects like antiviral, anti-inflammatory, analgesic, antidiabetic, antimicrobial, anti-parasitic, and antioxidant effects, thereby arresting the causal or symptomatic effects manifested in the pandemics. Ethnomedical and phytochemical studies on the African medicinal plants have led to the isolation of promising antiviral, anti-inflammatory, anti-parasitic, analgesic, and antimicrobial metabolites. Our discussion in this chapter is premised on challenging Africans Scientists (ethnobotanists, phytochemists, microbiologists, and pharmacologists) to collaboratively intensify the search for phytochemicals as drug leads and explore options for developing these leads into functional medicines for the various diseases/pandemics devastating the continent. 2025-09-02T16:16:45Z 2025-09-02T16:16:45Z 2022 Book chapter Buyinza, D., & Gumula, I. (2022). Fighting the next pandemic: A phytochemical approach from African flora – An overview. Society for the Advancement of Science in Africa. 978-0-2288-7440-9 http://hdl.handle.net/20.500.12493/2933 en application/pdf Society for the Advancement of Scienvce in Africa
spellingShingle Pandemic
herbal remedies
phytochemicals
drugs.
Buyinza, Daniel
Gumula, Ivan
Fighting the next pandemic: A phytochemical Approach from African flora - An overview
title Fighting the next pandemic: A phytochemical Approach from African flora - An overview
title_full Fighting the next pandemic: A phytochemical Approach from African flora - An overview
title_fullStr Fighting the next pandemic: A phytochemical Approach from African flora - An overview
title_full_unstemmed Fighting the next pandemic: A phytochemical Approach from African flora - An overview
title_short Fighting the next pandemic: A phytochemical Approach from African flora - An overview
title_sort fighting the next pandemic a phytochemical approach from african flora an overview
topic Pandemic
herbal remedies
phytochemicals
drugs.
url http://hdl.handle.net/20.500.12493/2933
work_keys_str_mv AT buyinzadaniel fightingthenextpandemicaphytochemicalapproachfromafricanfloraanoverview
AT gumulaivan fightingthenextpandemicaphytochemicalapproachfromafricanfloraanoverview