Diagnosis and Classification of Tuberculosis Chest X-ray Images of Children Less Than 15 years at Mbarara Regional Referral Hospital Using Deep Learning.

Tuberculosis (TB) is an underestimated cause of death in children, with only 45% of cases correctly diagnosed and reported. It is estimated that 1.12 million TB cases occurred among newborns, children, and adolescents aged less or equal 14 years. In Uganda, TB prevalence is 8.5% in children and 16.7...

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Main Authors: Kawuma, Simon, Kumbakumba, Elias, Mabirizi, Vicent, Nanjebe, Deborah, Mworozi, Kenneth, Mukama, Adolf Oyesigye, Kyasimire, Lydia
Format: Article
Language:English
Published: Kabale University 2024
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Online Access:http://hdl.handle.net/20.500.12493/2318
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author Kawuma, Simon
Kumbakumba, Elias
Mabirizi, Vicent
Nanjebe, Deborah
Mworozi, Kenneth
Mukama, Adolf Oyesigye
Kyasimire, Lydia
author_facet Kawuma, Simon
Kumbakumba, Elias
Mabirizi, Vicent
Nanjebe, Deborah
Mworozi, Kenneth
Mukama, Adolf Oyesigye
Kyasimire, Lydia
author_sort Kawuma, Simon
collection KAB-DR
description Tuberculosis (TB) is an underestimated cause of death in children, with only 45% of cases correctly diagnosed and reported. It is estimated that 1.12 million TB cases occurred among newborns, children, and adolescents aged less or equal 14 years. In Uganda, TB prevalence is 8.5% in children and 16.7% in adolescents. Treatment and diagnosing TB is challenging and its high mortality rate is due to many lacks in the diagnosis of this illness especially among children. As a strategy to curb TB mortality rate in children, there exists a need to improve and expedite the screening for TB among children. Chest X-ray (CXR) is commonly used in TB burdened countries like Uganda to diagnose TB patients but interpretation of the patient’s radiograph needs skilled radiologists who are few. To this end, this research aims to close the TB mortality gap in children by applying AI, primarily deep learning techniques, to detect TB in children. The study created five models, one from scratch and four pre-trained Transfer Learning (TL) and were trained and verified using digital CXR radiograph images of children who visit the TB clinic at Mbarara Regional Referral Hospital. The model classifies clinical images of patients into normal or Tuberculosis. TL models; VGG16, VGG19, Inception V3, and ResNet50 outperformed scratch model with validation accuracy of 79.91%, 69.21%, 53.0%, 51.09% and 50.01% respectively. We hope that once the deep learning models are implemented and adopted by the radiologist, it will reduce the time spent by radiologist while analysing CXR images.
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spelling oai:idr.kab.ac.ug:20.500.12493-23182024-10-15T00:01:24Z Diagnosis and Classification of Tuberculosis Chest X-ray Images of Children Less Than 15 years at Mbarara Regional Referral Hospital Using Deep Learning. Kawuma, Simon Kumbakumba, Elias Mabirizi, Vicent Nanjebe, Deborah Mworozi, Kenneth Mukama, Adolf Oyesigye Kyasimire, Lydia Artificial Intelligence Models Deep Learning Tuberculosis Chest X-ray Convolution Neural Network Tuberculosis (TB) is an underestimated cause of death in children, with only 45% of cases correctly diagnosed and reported. It is estimated that 1.12 million TB cases occurred among newborns, children, and adolescents aged less or equal 14 years. In Uganda, TB prevalence is 8.5% in children and 16.7% in adolescents. Treatment and diagnosing TB is challenging and its high mortality rate is due to many lacks in the diagnosis of this illness especially among children. As a strategy to curb TB mortality rate in children, there exists a need to improve and expedite the screening for TB among children. Chest X-ray (CXR) is commonly used in TB burdened countries like Uganda to diagnose TB patients but interpretation of the patient’s radiograph needs skilled radiologists who are few. To this end, this research aims to close the TB mortality gap in children by applying AI, primarily deep learning techniques, to detect TB in children. The study created five models, one from scratch and four pre-trained Transfer Learning (TL) and were trained and verified using digital CXR radiograph images of children who visit the TB clinic at Mbarara Regional Referral Hospital. The model classifies clinical images of patients into normal or Tuberculosis. TL models; VGG16, VGG19, Inception V3, and ResNet50 outperformed scratch model with validation accuracy of 79.91%, 69.21%, 53.0%, 51.09% and 50.01% respectively. We hope that once the deep learning models are implemented and adopted by the radiologist, it will reduce the time spent by radiologist while analysing CXR images. 2024-10-14T09:52:09Z 2024-10-14T09:52:09Z 2024 Article Kawuma, Simon et al. (2024). Diagnosis and Classification of Tuberculosis Chest X-ray Images of Children Less Than 15 years at Mbarara Regional Referral Hospital Using Deep Learning. Kabale: Kabale University, http://hdl.handle.net/20.500.12493/2318 en Attribution-NonCommercial-NoDerivs 3.0 United States http://creativecommons.org/licenses/by-nc-nd/3.0/us/ application/pdf Kabale University
spellingShingle Artificial Intelligence
Models
Deep Learning
Tuberculosis
Chest X-ray
Convolution Neural Network
Kawuma, Simon
Kumbakumba, Elias
Mabirizi, Vicent
Nanjebe, Deborah
Mworozi, Kenneth
Mukama, Adolf Oyesigye
Kyasimire, Lydia
Diagnosis and Classification of Tuberculosis Chest X-ray Images of Children Less Than 15 years at Mbarara Regional Referral Hospital Using Deep Learning.
title Diagnosis and Classification of Tuberculosis Chest X-ray Images of Children Less Than 15 years at Mbarara Regional Referral Hospital Using Deep Learning.
title_full Diagnosis and Classification of Tuberculosis Chest X-ray Images of Children Less Than 15 years at Mbarara Regional Referral Hospital Using Deep Learning.
title_fullStr Diagnosis and Classification of Tuberculosis Chest X-ray Images of Children Less Than 15 years at Mbarara Regional Referral Hospital Using Deep Learning.
title_full_unstemmed Diagnosis and Classification of Tuberculosis Chest X-ray Images of Children Less Than 15 years at Mbarara Regional Referral Hospital Using Deep Learning.
title_short Diagnosis and Classification of Tuberculosis Chest X-ray Images of Children Less Than 15 years at Mbarara Regional Referral Hospital Using Deep Learning.
title_sort diagnosis and classification of tuberculosis chest x ray images of children less than 15 years at mbarara regional referral hospital using deep learning
topic Artificial Intelligence
Models
Deep Learning
Tuberculosis
Chest X-ray
Convolution Neural Network
url http://hdl.handle.net/20.500.12493/2318
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