Effect of Vigorous-Intensity Physical Activity on Incident Cognitive Impairment in High-Risk Hypertension.
Introduction: We investigated the effect of vigorous physical activity (VPA) on the risk of incident mild cognitive impairment (MCI) and probable dementia among individuals with high-risk hypertension. Methods: Baseline self-reported frequency of VPA was categorized into low VPA (<1 session/week)...
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| Language: | en_US |
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Kabale University
2024
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| Online Access: | http://hdl.handle.net/20.500.12493/2059 |
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| author | Kazibwe, Richard Schaich, Christopher L. Muhammad, Ahmad Imtiaz Epiu, Isabella Namutebi, Juliana H. Chevli, Parag A. Kazibwe, Joseph Hughes, Timothy Rikhi, Rishi R. Shapiro, Michael D. Yeboah, Joseph |
| author_facet | Kazibwe, Richard Schaich, Christopher L. Muhammad, Ahmad Imtiaz Epiu, Isabella Namutebi, Juliana H. Chevli, Parag A. Kazibwe, Joseph Hughes, Timothy Rikhi, Rishi R. Shapiro, Michael D. Yeboah, Joseph |
| author_sort | Kazibwe, Richard |
| collection | KAB-DR |
| description | Introduction: We investigated the effect of vigorous physical activity (VPA) on the risk of incident mild cognitive impairment (MCI) and probable dementia among individuals with high-risk hypertension.
Methods: Baseline self-reported frequency of VPA was categorized into low VPA (<1 session/week), and high VPA (≥1 session/week). We used multivariate Cox regression analysis to examine the association of VPA categories with incident MCI and probable dementia events.
Results: Participants in the high VPA category, compared with low VPA, experienced lower events rates (per 1000 person-years) of MCI (13.9 vs 19.7), probable dementia (6.3 vs 9.0), and MCI/probable dementia (18.5 vs 25.8). In the multivariate Cox regression model, high VPA, compared with low VPA, was associated with lower risk of MCI, probable dementia, and MCI/probable dementia (HR [95% CI]: 0.81 [0.68–0.97], 0.80 [0.63–1.03], and 0.82 [0.70–0.96]), respectively.
DISCUSSION: This study provides evidence that VPA may preserve cognitive function
in high-risk patients with hypertension. |
| format | Article |
| id | oai:idr.kab.ac.ug:20.500.12493-2059 |
| institution | KAB-DR |
| language | en_US |
| publishDate | 2024 |
| publisher | Kabale University |
| record_format | dspace |
| spelling | oai:idr.kab.ac.ug:20.500.12493-20592024-08-01T00:03:02Z Effect of Vigorous-Intensity Physical Activity on Incident Cognitive Impairment in High-Risk Hypertension. Kazibwe, Richard Schaich, Christopher L. Muhammad, Ahmad Imtiaz Epiu, Isabella Namutebi, Juliana H. Chevli, Parag A. Kazibwe, Joseph Hughes, Timothy Rikhi, Rishi R. Shapiro, Michael D. Yeboah, Joseph Cognitive Impairment Dementia Hypertension Mild Cognitive Impairment Physical Activity Introduction: We investigated the effect of vigorous physical activity (VPA) on the risk of incident mild cognitive impairment (MCI) and probable dementia among individuals with high-risk hypertension. Methods: Baseline self-reported frequency of VPA was categorized into low VPA (<1 session/week), and high VPA (≥1 session/week). We used multivariate Cox regression analysis to examine the association of VPA categories with incident MCI and probable dementia events. Results: Participants in the high VPA category, compared with low VPA, experienced lower events rates (per 1000 person-years) of MCI (13.9 vs 19.7), probable dementia (6.3 vs 9.0), and MCI/probable dementia (18.5 vs 25.8). In the multivariate Cox regression model, high VPA, compared with low VPA, was associated with lower risk of MCI, probable dementia, and MCI/probable dementia (HR [95% CI]: 0.81 [0.68–0.97], 0.80 [0.63–1.03], and 0.82 [0.70–0.96]), respectively. DISCUSSION: This study provides evidence that VPA may preserve cognitive function in high-risk patients with hypertension. 2024-06-07T15:26:15Z 2024-06-07T15:26:15Z 2024 Article Kazibwe, Richard et al. (2024). Effect of Vigorous-Intensity Physical Activity on Incident Cognitive Impairment in High-Risk Hypertension. Kabale: Kabale University. http://hdl.handle.net/20.500.12493/2059 en_US application/pdf Kabale University |
| spellingShingle | Cognitive Impairment Dementia Hypertension Mild Cognitive Impairment Physical Activity Kazibwe, Richard Schaich, Christopher L. Muhammad, Ahmad Imtiaz Epiu, Isabella Namutebi, Juliana H. Chevli, Parag A. Kazibwe, Joseph Hughes, Timothy Rikhi, Rishi R. Shapiro, Michael D. Yeboah, Joseph Effect of Vigorous-Intensity Physical Activity on Incident Cognitive Impairment in High-Risk Hypertension. |
| title | Effect of Vigorous-Intensity Physical Activity on Incident Cognitive Impairment in High-Risk Hypertension. |
| title_full | Effect of Vigorous-Intensity Physical Activity on Incident Cognitive Impairment in High-Risk Hypertension. |
| title_fullStr | Effect of Vigorous-Intensity Physical Activity on Incident Cognitive Impairment in High-Risk Hypertension. |
| title_full_unstemmed | Effect of Vigorous-Intensity Physical Activity on Incident Cognitive Impairment in High-Risk Hypertension. |
| title_short | Effect of Vigorous-Intensity Physical Activity on Incident Cognitive Impairment in High-Risk Hypertension. |
| title_sort | effect of vigorous intensity physical activity on incident cognitive impairment in high risk hypertension |
| topic | Cognitive Impairment Dementia Hypertension Mild Cognitive Impairment Physical Activity |
| url | http://hdl.handle.net/20.500.12493/2059 |
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