Effect of Vigorous-Intensity Physical Activity on Incident Cognitive Impairment in High-Risk Hypertension.
Introduction: We investigated the effect of vigorous physical activity (VPA) on the risk of incident mild cognitive impairment (MCI) and probable dementia among individuals with high-risk hypertension. Methods: Baseline self-reported frequency of VPA was categorized into low VPA (<1 session/week)...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | en_US |
| Published: |
Kabale University
2024
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.12493/2059 |
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| Summary: | Introduction: We investigated the effect of vigorous physical activity (VPA) on the risk of incident mild cognitive impairment (MCI) and probable dementia among individuals with high-risk hypertension.
Methods: Baseline self-reported frequency of VPA was categorized into low VPA (<1 session/week), and high VPA (≥1 session/week). We used multivariate Cox regression analysis to examine the association of VPA categories with incident MCI and probable dementia events.
Results: Participants in the high VPA category, compared with low VPA, experienced lower events rates (per 1000 person-years) of MCI (13.9 vs 19.7), probable dementia (6.3 vs 9.0), and MCI/probable dementia (18.5 vs 25.8). In the multivariate Cox regression model, high VPA, compared with low VPA, was associated with lower risk of MCI, probable dementia, and MCI/probable dementia (HR [95% CI]: 0.81 [0.68–0.97], 0.80 [0.63–1.03], and 0.82 [0.70–0.96]), respectively.
DISCUSSION: This study provides evidence that VPA may preserve cognitive function
in high-risk patients with hypertension. |
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